Biomedical Research Centres

Formed through partnerships between England’s leading NHS organisations and universities, 20 NIHR Biomedical Research Centres conduct translational research to transform scientific breakthroughs into life-saving treatments for patients.

Staffed by expert investigators and clinicians, NIHR BRCs are leaders in translating lab-based discoveries into new cutting edge treatments, technologies, diagnostics and other interventions in clinical settings.

The aims of NIHR BRCs are to:

  • drive innovation in the prevention, diagnosis and treatment of ill-health
  • translate advances in biomedical research into benefits for patients
  • provide a key component of the NHS contribution to our nation’s international competitiveness by making the best Centres even better.

The substantial levels of sustained funding which BRCs receive creates an environment in which scientific endeavour can thrive, attract the foremost talent and produce world-class outputs, hence contributing to the nation’s international competitiveness as a major component of our knowledge economy.

BRC research themes

BRCs host research themes across a range of disease and therapeutic areas and each BRC has substantial portfolio either across a range of clinical and research areas, or in a specific clinical or research area. Details of the BRCs and their research themes are presented in the table below.

 

BRC Name

Name including host organisation and academic partner

Research themes

Funding for 5 years from 1 April 2017

NIHR Barts Biomedical Research Centre

NIHR Biomedical Research Centre at Barts Health NHS Trust and Queen Mary University of London

Cardiovascular devices and innovative trials, inherited cardiovascular disorders.

£6,557,380

NIHR Birmingham Biomedical Research Centre

NIHR Biomedical Research Centre at University Hospitals Birmingham NHS Foundation Trust and the University of Birmingham

Inflammatory arthritis, inflammatory bowel disease, inflammatory sarcopaenia.

£12,120,962

NIHR Bristol Biomedical Research Centre

NIHR Biomedical Research Centre at University Hospitals Bristol NHS Foundation Trust and the University of Bristol

Cardiovascular disease, mental health, nutrition, diet and lifestyle (including obesity), reproductive and perinatal health, surgical innovation.

£20,858,545

NIHR Cambridge Biomedical Research Centre

NIHR Biomedical Research Centre at Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge

Antimicrobial resistance, cancer, cardiovascular and respiratory disease, dementia and neurodegenerative disease, gastrointestinal disease, integrative genomics, mental health, metabolism, endocrinology and bone, neuroscience, nutrition, diet and lifestyle, population and quantitative science, transplantation and regenerative science, women’s health and paediatrics.

£114,300,000

NIHR Manchester Biomedical Research Centre

NIHR Biomedical Research Centre at Central Manchester University Hospitals NHS Foundation Trust and the University of Manchester

Advanced radiotherapy, cancer prevention and early detection, cancer precision medicine, dermatology, hearing health, respiratory medicine, targeted therapy in musculoskeletal diseases

£28,500,000

NIHR Great Ormond Street Hospital Biomedical Research Centre

NIHR Biomedical Research Centre at Great Ormond Street Hospital for Children NHS Foundation Trust and University College London

Advanced treatments for structural malformation and tissue damage, gene, stem and cellular therapies, genomics and systems medicine, novel therapeutics and their translation into childhood disease.

£37,005,790

NIHR Guy's and St Thomas' Biomedical Research Centre

NIHR Biomedical Research Centre at Guy's and St Thomas' NHS Foundation Trust and King's College London

Cardiovascular disease, cutaneous medicine, genomic medicine, imaging sciences, infection and immunity, oral health, regenerative medicine and cellular therapy, transplantation, women and children’s health.

£64,400,267

NIHR Imperial Biomedical Research Centre

NIHR Biomedical Research Centre at Imperial College Healthcare NHS Trust and Imperial College London

Brain sciences, cancer, cardiovascular, gut health, immunology, infection and AMR, metabolic medicine and endocrine, surgery and technology

£90,008,746

NIHR Leeds Biomedical Research Centre

NIHR Biomedical Research Centre at Leeds Teaching Hospitals NHS Trust and the University of Leeds

Preventing disease and disability in immune mediated inflammatory disease, improving treatment of osteoarthritis

£6,736,575

NIHR Leicester Biomedical Research Centre

NIHR Biomedical Research Centre at University Hospitals of Leicester NHS Trust and the University of Leicester

Cardiovascular, lifestyle, respiratory.

£11,591,314

NIHR Maudsley Biomedical Research Centre

NIHR Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London

Affective disorders and interface with medicine, bioinformatics and statistics, biomarkers and genomics, child and neurodevelopmental disorders, clinical and population informatics, dementia and related disorders, mobile health, neuroimaging, obesity, pain, patient and carer involvement and engagement, psychosis and neuropsychiatry, substance use, translational therapeutics.

£65,977,500

NIHR Moorfields Biomedical Research Centre

NIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology

Gene therapy, genomic medicine and informatics, inflammation and immunotherapy, regenerative medicine and pharmaceutics, visual assessment and imaging.

£19,075,000

NIHR Newcastle Biomedical Research Centre

NIHR Biomedical Research Centre at Newcastle upon Tyne Hospitals NHS Foundation Trust and Newcastle University

Dementia, liver disease, musculoskeletal disease, neuromuscular disease, skin and oral disease.

£16,208,633

NIHR Nottingham Biomedical Research Centre

NIHR Biomedical Research Centre at Nottingham University Hospitals NHS Trust and the University of Nottingham

Deafness and hearing problems, gastrointestinal and liver disorders, mental health and technology, musculoskeletal disease, respiratory disease.

£23,642,003

NIHR Oxford Biomedical Research Centre

NIHR Biomedical Research Centre at Oxford University Hospitals NHS Foundation Trust and the University of Oxford

Antimicrobial resistance and microbiology, cardiovascular, diabetes and metabolism, gastroenterology and mucosal immunity, genomic medicine, haematology and stem cells, multi-modal cancer therapies, multimorbidity and long term conditions, musculoskeletal, neurological conditions, obesity, diet and lifestyle, respiratory, stroke and vascular dementia, surgical innovation and evaluation, technology and digital health, vaccines for emerging and endemic diseases.

£113,718,800

NIHR Oxford Health Biomedical Research Centre

NIHR Biomedical Research Centre at Oxford Health NHS Foundation Trust and the University of Oxford

Adult mental health, older adults and dementia, precision psychological treatments

£12,824,900

NIHR Royal Marsden Biomedical Research Centre

NIHR Biomedical Research Centre at The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research

Breast cancer, gastrointestinal cancers, novel cancer therapeutics, prostate cancer, targeted physical therapies, uncommon cancers.

£43,074,315

NIHR Sheffield Biomedical Research Centre

NIHR Biomedical Research Centre at Sheffield Teaching Hospitals NHS Foundation Trust and the University of Sheffield

Translational neuroscience for chronic neurological disorders.

£4,049,681

NIHR Southampton Biomedical Research Centre

NIHR Biomedical Research Centre at University Hospitals Southampton NHS Foundation Trust and the University of Southampton

Life-course nutrition, lifestyle and health, respiratory and critical care.

£14,509,067

NIHR University College London Hospitals Biomedical Research Centre

NIHR Biomedical Research Centre at University College London Hospitals NHS Foundation Trust and University College London

Cancer, cardiovascular disease, deafness and hearing, dementia and mental health, immunity, inflammation and immunotherapeutics, neurological diseases, obesity, oral health and disease.

£111,503,317

Further information

Detailed information about the resources and capabilities of the existing BRCs is available at the UK Experimental Medicine Resource Finder website, or contact the NIHR Office for Clinical Research Infrastructure at nocri@nihr.ac.uk. There is also an NIHR briefing document.