Biomedical Research Centres

Formed through partnerships between England’s leading NHS organisations and universities, 11 NIHR Biomedical Research Centres conduct translational research to transform scientific breakthroughs into life-saving treatments for patients.

Staffed by expert investigators and clinicians, NIHR BRCs are leaders in translating lab-based discoveries into new cutting edge treatments, technologies, diagnostics and other interventions in clinical settings. BRCs host research themes across a range of disease and therapeutic areas including: cancer, cardiovascular, dementia, endocrinology and metabolism, gastroenterology and hepatology, genetics and genomics, musculoskeletal, neuroscience, nutrition and lifestyle, ageing, paediatrics, respiratory disease, stroke, surgical innovation.

The substantial levels of sustained funding which BRCs receive creates an environment in which scientific endeavour can thrive, attract the foremost talent and produce world-class outputs, hence contributing to the nation’s international competitiveness as a major component of our knowledge economy. BRCs (along with NIHR Biomedical Research Units) form the bedrock of the first two NIHR Translational Research Partnerships.

The aims of NIHR BRCs are to:

  • drive innovation in the prevention, diagnosis and treatment of ill-health
  • translate advances in biomedical research into benefits for patients
  • provide a key component of the NHS contribution to our nation’s international competitiveness by making the best Centres even better.

BRC Research Themes
Each BRC has either a very substantial portfolio of world-class biomedical research across a range of clinical and research areas, or a substantial portfolio of world-class biomedical research in a specific clinical or research area.

Details of the BRCs and their research themes are presented in the table below:

 

Name

Name including host organisation and
academic partner

Research themes

Funding for five years from
1 April 2012

NIHR Cambridge Biomedical Research Centre

NIHR Biomedical Research Centre at Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge

Brain Injury and Repair; Cancer; Cardiovascular Disease; Dementia and Neurodegenerative Disorders; Genomics; Immunity, Infection and Inflammation; Mental Health; Metabolism, Endocrinology and Bone; Population Health Science; Transplantation and Regenerative Medicine; Women’s Health

£110,073,288

NIHR Great Ormond Street Biomedical Research Centre

NIHR Biomedical Research Centre at Great Ormond Street Hospital for Children NHS Trust and University College London

Molecular Basis of Childhood Disease; Diagnostics and Imaging in Childhood Disease; Gene, Stem and Cellular Therapies; Novel Therapies for Childhood Diseases

£35,660,795

NIHR Guy's and St Thomas' Biomedical Research Centre

NIHR Biomedical Research Centre at Guy's and St Thomas' NHS Foundation Trust and King's College London

Cancer; Cardiovascular Disease; Cutaneous Medicine; Environment, Respiratory Health and Allergy; Imaging and Bioengineering; Infection and Immunity; Transplantation; Translational Genetics

£58,724,775

NIHR Imperial Biomedical Research Centre

NIHR Biomedical Research Centre at Imperial College Healthcare NHS Trust and Imperial College London

Biobanking; Cancer; Cardiovascular; Gastroenterology and Hepatology; Genetics and Genomics; Imaging; Haematology; Infection; Interventional Public Health; Neonatal Medicine; Neuroscience; Obesity, Diabetes, Endocrinology and Metabolism; Paediatrics; Renal Medicine and Transplantation; Respiratory; Rheumatology; Stratified Medicine; Surgery and Technology; Women’s Health

£112,992,915

NIHR Moorfields Biomedical Research Centre 

NIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology

Gene Therapy; Genotyping, Phenotyping and Informatics; Inflammation and Immunotherapy;  New Technologies and Devices; Regenerative Medicine and Pharmaceutics; Visual Assessment and Imaging

£26,548,596

NIHR Newcastle Biomedical Research Centre

NIHR Biomedical Research Centre at Newcastle upon Tyne Hospitals NHS Foundation Trust and Newcastle University

The Ageing Body; The Ageing Brain; The Ageing Limbs; Genomics; Fibrosis & Repair; Mitochondria & Neuromuscular Disease

£16,636,125

NIHR Oxford Biomedical Research Centre

NIHR Biomedical Research Centre at Oxford University Hospitals NHS Trust and the University of Oxford

Biomedical Informatics and Technology; Blood; Cancer; Cardiovascular; Dementia and Cardiovascular Disease; Diabetes; Functional Neuroscience and Imaging; Genomic Medicine; Immunity and Inflammation; Infection; Prevention and Population Care; Surgical Innovation and Evaluation; Translational Physiology; Vaccines

£97,988,771

NIHR Royal Marsden Biomedical Research Centre 

NIHR Biomedical Research Centre at The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research

Breast Cancer; Cancer Genetics; Cancer Imaging; Cancer Therapeutics; Clinical Studies; Molecular Pathology; Prostate Cancer; Radiotherapy

£61,543,735

NIHR Southampton Biomedical Research Centre

NIHR Biomedical Research Centre at University Hospitals Southampton NHS Foundation Trust and the University of Southampton

Nutrition, Growth and Development; Nutrition, Lifestyle and Healthy Ageing

£9,677,372

NIHR Maudsley Biomedical Research Centre

NIHR Biomedical Research Centre at the South London and Maudsley NHS Foundation Trust and King's College London

Bioinformatics and Statistics; BioResource, Biomarkers and Genomics; Clinical and Population Informatics; Developmental Disorders; Disorders of Affect and Addiction and Their Interface with Medicine; Neuroimaging; Neuropsychiatric Disorders; Patient and Carer Participation; Clinical Trials - Innovation and Implementation 

£48,873,298

NIHR University College London Hospitals Biomedical Research Centre 

NIHR Biomedical Research Centre at University College London Hospitals NHS Foundation Trust and University College London

Cancer; Cardiometabolic; Infection, Immunity and Inflammation; Neuroscience

£98,204,505

 

Competition for NIHR Biomedical Research Centre (BRC) funding

A new, open competition for NIHR Biomedical Research Centre (BRC) funding has been launched. Funding to the NHS partner is over a five year period, from 1 April 2017 to 31 March 2022. All applications will be reviewed by an independent International Selection Panel who will make recommendations on Biomedical Research Centre designation and funding. The NIHR BRCs will be funded to support people- and/or patient-focused early translational (experimental medicine) research, the aim of which is to translate discoveries from basic/discovery science into clinical research, and through to benefits for patients, the health system and for broader economic gain.

The closing date for submission of pre-qualifying questionnaires (PQQ) by NHS/University partnerships that are interested in being considered for an NIHR BRC was 15 February 2016 at 13:00.

We do not expect to shortlist any NHS/University partnership where the academic partner, for example, the Medical School/Faculty of Medicine, has not achieved at least the Silver Award of the Athena SWAN Charter for Women in Science.

Further Information

Detailed information about the resources and capabilities of the existing BRCs is available at the UK Experimental Medicine Resource Finder website, or contact the NIHR Office for Clinical Research Infrastructure at nocri@nihr.ac.uk. There is also an NIHR briefing document