Information about Clinical Research carried in the NHS which is supported by the NIHR
NIHR Clinical Research Network Portfolio
The NIHR now brings together government support for research in the NHS in England, through the NIHR Clinical Research Network Coordinating Centre (CRNCC).
The NIHR CRN Portfolio is a database of clinical research studies being undertaken in the NHS, that are supported by the NIHR Clinical Research Network (CRN) in England.
Details of clinical research studies which meet specific eligibility criteria are recorded in a database known as the UK Clinical Research Network Portfolio, which comprises the NIHR CRN Portfolio in England and the corresponding Portfolios of Northern Ireland, Scotland and Wales.
National Research Register Archive
Until the creation of the CRN Portfolio database, the National Research Register (NRR) provided information on research taking place in NHS organisations in England, Scotland and Wales. The development of Clinical Research Networks shifted the responsibility for registering eligible research from NHS organisations to the researcher and the topic network.
The National Research Register Archive has been established as a public resource to support historical analysis. The NRR Archive contains data collected up to September 2007. It is possible to make amendments to this data for legal or accuracy reasons, but no new records can be added to the archive.
CRD databases of research evidence
The evidence base for the effectiveness and cost-effectiveness of health care interventions is growing rapidly. For clinicians and decision-makers this research literature can be difficult and time consuming to identify and appraise.
Funded by NIHR, the CRD databases are produced by the Centre for Reviews and Dissemination at the University of York to help decision makers identify and interpret an increasingly complex and technical literature. The databases include thousands of critical summaries of quality assessed systematic reviews and economic evaluations, and information about and links to thousands of completed and on-going health technology assessments.
DARE is focused on systematic reviews that evaluate the effects of health care interventions and the delivery and organisation of health services, NHS EED on the economic evaluation of health care interventions, and the HTA database on health technology assessments provided by HTA organisations from around the world. PROSPERO, our international prospective register of systematic reviews, provides information about on-going systematic reviews and serves to help reduce reporting bias and avoid unplanned duplication of effort.