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News: Effects of stress on brain cells offer clues to new anti-depressant drugs

Title

Effects of stress on brain cells offer clues to new anti-depressant drugs 

News Title

Effects of stress on brain cells offer clues to new anti-depressant drugs 

News Content

Research from King’s College London reveals the detailed mechanism behind how stress hormones reduce the number of new brain cells - a process considered to be linked to depression.  The researchers identified a key protein responsible for the long-term detrimental effect of stress on cells, and importantly, successfully used a drug compound to block this effect, offering a potential new avenue for drug discovery. The study, published in Proceedings of the National Academy of Sciences was co-funded by the NIHR’s Biomedical Research Centre for Mental Health at the South London and Maudsley NHS Foundation Trust and King’s College London. This novel mechanism may lead to new pharmacological treatments aimed at reducing the levels of SGK1 in depressed patients.

News Link

Kings College London news release 

News Date

15/05/2013 

Expires

14/06/2013 

Date Created

 

Date Modified

 
Attachments
Created at 15/05/2013 17:41  by Leonilde Yahyaoui 
Last modified at 15/05/2013 17:41  by Leonilde Yahyaoui