Clinical Research Network

NIHR Clinical Research Network

Research team in the lab

The NIHR Clinical Research Network Coordinating Centre manages the Clinical Research Network (CRN) on behalf of the Department of Health and Social Care. The CRN makes it possible for patients and health professionals across England to participate in clinical research studies, in both the NHS and in the wider health and social care environment.

The CRN provides the infrastructure that allows high-quality clinical research funded by charities, research funders and life-sciences industry to be undertaken in both the NHS and in the wider health and social care environment. We work with patients and the public to make sure their needs are placed at the heart of all research, and providing opportunities for patients to gain earlier access to new and better treatments through research participation.

Patient smiling with nurse

The NIHR Clinical Research Network Coordinating Centre (CRNCC) is hosted jointly by Guy’s and St Thomas’ NHS Foundation Trust and the University of Leeds, supported by a wider partnership which also includes King’s College London, Imperial College London, Newcastle University, and the University of Liverpool.


The CRNCC enables the CRN to support around 5000 clinical research studies each year. The collection of all studies we support is the CRN Portfolio.


The CRN meets the costs of NHS staff that support research and provides specialist training so that patients can be confident that research is being delivered by trained, experienced front-line NHS staff.


We meet the costs of using NHS facilities, such as scanners and x-rays that are needed in the course of a study, so that research is not subsidised with funding that has been provided for patient care.


We provide practical help in identifying and recruiting patients for Portfolio studies, so that researchers can be confident of completing the study on time and as planned.


The Clinical Research Network is made up of 15 Local Clinical Research Networks that cover the length and breadth of England. The CRN delivers research across 30 specialty therapy areas at both national and local level. Find out about the Local Clinical Research Network (LCRN) funding allocations for the 2018/19 financial year here.

Nurse taking patients blood

Our Performance

Child with stethoscope

Key Statistics

Scientist with pipette

Our Structure

Patient being scanned

Meet the Team

Man on an exercise bike

Contact us

Patient eye examination

CRN system support

Clinical staff having a discussion

Study support service

Nurse monitoring patient

CRN Portfolio