Case Studies - NIHR / Industry Collaboration

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Case studies of collaborative work between the NIHR clinical research infrastructure and industry.

NOCRI case study - Head Up Collar

The Head Up Collar

Many people with neurological conditions develop neck muscle weakness, leading to pain and restricted movement, as well as problems with swallowing, breathing and communication. The Head Up Collar helps to alleviate these problems.

Bioimpedance spectroscopy to maintain renal output: the BISTRO Trial

The NIHR Devices for Dignity Healthcare Technology Co-operative is collaborating on a project to test whether taking regular measurements with a bioimpedance device improves outcomes for people who have recently started haemodialysis treatment for their kidney failure.


Customised non-invasive ventilation masks for children

The NIHR Devices for Dignity Healthcare Technology Cooperative has supported the development of customised non-invasive ventilation interfaces for children for whom current commercial masks are unavailable or unsuitable. These customised masks can save lives by improving ventilation therapies and reduce complications. 


Next generation solutions in renal care without compromising on performance

The NIHR has supported Quanta Dialysis Technologies in the development of SC+, a high performance, compact, easy-to-use haemodialysis system designed to improve the lives of patients and carers both in the clinic and the home.


Development of a new screening tool for bowel cancer 

The NIHR Office for Clinical research Infrastructure provides support to an SME, coordinating access to NIHR experts to develop a new 'hands-free' method of bowel cancer screening that has the potential to boost participation in screening programmes.

  Development a new inhaled therapy for COPD 

NIHR researchers collaborate with an industry partner to evaluate the safety, tolerability and efficacy of an inhaled therapeutic in patients with chronic obstructive pulmonary disease. 


New Gene Therapy for Parkinson’s Disease

NIHR researchers collaborate with industry to conduct a UK first-in-man gene therapy trial for Parkinson’s disease, delivering the synthetic enzymes for dopamine (ProSavin®) into patient’s brains.


Advances in Cell Therapy for Huntington’s  Disease

A safety study involving the transplantation of human fetal striatal tissue into the striatum of four patients with Huntington’s disease has demonstrated that the procedure is safe and feasible.


Bringing flexibility and adaptability to trials seeking advances in bowel cancer treatment

NIHR researchers collaborate in the FOCUS4 trial programme to test new cancer drugs in patients with different subtypes of advanced and incurable bowel cancer.


Developing Advanced Orthopaedic Implants For Osteoarthritis Patients

The NIHR is collaborating with industry partners, using advanced computer modelling and biobanking to develop optimised orthopaedic implants for an ageing population.


Fast-tracking lung cancer diagnosis

The successful treatment of lung cancer relies on early and effective diagnosis. The NIHR is collaborating with industry to develop an advanced screening method to detect lung cancer before patients develop symptoms.


Blood test - a simple diagnosis for Alzheimer’s?

The NIHR is collaborating with industry in biomarker research that has significant potential to form the basis of simple blood tests for the diagnosis and management of Alzheimer’s disease.


Duchenne muscular dystrophy - a stratified approach

NIHR researchers are collaborating with industry partners to develop a novel therapy to improve treatment outcomes in duchenne muscular dystrophy patients who possess an appropriate genotype.