NIHR Biomedical Research Centres (BRCs)

Formed through partnerships between England’s leading NHS organisations and universities, 20 NIHR Biomedical Research Centres (BRCs) conduct translational research to transform scientific breakthroughs into life-saving treatments for patients.

Staffed by expert investigators and clinicians, NIHR BRCs are leaders in translating lab-based discoveries into new cutting edge treatments, technologies, diagnostics and other interventions in clinical settings.

The aims of NIHR BRCs are to:

  • drive innovation in the prevention, diagnosis and treatment of ill-health
  • translate advances in biomedical research into benefits for patients
  • provide a key component of the NHS contribution to our nation’s international competitiveness by making the best Centres even better.

The substantial levels of sustained funding that NIHR BRCs receive creates an environment in which scientific endeavour can thrive, attract the foremost talent and produce world-class outputs, hence contributing to the nation’s international competitiveness as a major component of our knowledge economy.

NIHR BRC research themes

NIHR BRCs host research themes across a range of disease and therapeutic areas, and each NIHR BRC has substantial portfolio either across a range of clinical and research areas, or in a specific clinical or research area. Details of the NIHR BRCs and their research themes are presented in the table below.

BRC map

 

BRC Name

Name including host organisation and academic partner

Research themes

Funding for 5 years from 1 April 2017

NIHR Barts Biomedical Research Centre

NIHR Biomedical Research Centre at Barts Health NHS Trust and Queen Mary University of London

Cardiovascular Devices and Innovative Trials, Inherited Cardiovascular Disorders, Health Informatics, Advanced Imaging and the Barts Bioresource.

£6,557,380

NIHR Birmingham Biomedical Research Centre

NIHR Biomedical Research Centre at University Hospitals Birmingham NHS Foundation Trust and the University of Birmingham

Inflammatory Arthritis, Inflammatory Gastroenterology, Inflammatory Sarcopaenia, Diagnostics & Biomarkers, Entrepreneurship and Commercialisation, Trial Design and Delivery.

£12,120,962

NIHR Bristol Biomedical Research Centre

NIHR Biomedical Research Centre at University Hospitals Bristol NHS Foundation Trust and the University of Bristol

Cardiovascular Disease, Mental Health, Nutrition, Diet and Lifestyle (including obesity), Reproductive and Perinatal Health, Surgical Innovation, Biostatistics, evidence synthesis and informatics, Training, PPI and PPE, Translational population science.

£20,858,545

NIHR Cambridge Biomedical Research Centre

NIHR Biomedical Research Centre at Cambridge University Hospitals NHS Foundation Trust and the University of Cambridge

Antimicrobial Resistance, Cancer, Cardiovascular and Respiratory Disease, Dementia and Neurodegenerative Disease, Gastrointestinal Disease, Integrative Genomics, Mental Health, Metabolism, Endocrinology and Bone, Neuroscience, Nutrition, Diet and Lifestyle, Population and Quantitative Sciences, Transplantation and Regenerative Medicine, Women's Health and Paediatrics, Capacity Development, Clinical Research Facility, Imaging, Inflammation, Infection and Immunotherapeutics.

£114,300,000

NIHR Great Ormond Street Hospital Biomedical Research Centre

NIHR Biomedical Research Centre at Great Ormond Street Hospital for Children NHS Foundation Trust and University College London

Advanced Treatments for Structural Malformation and Tissue Damage, Gene, Stem and Cellular Therapies, Genomics and Systems Medicine, Novel Therapies and their Translation into Childhood Disease, CRF High-End Inpatient Care, Education/Training: the BRC Experimental Medicine Academy, GOSH Rare Disease Cohorts, Translational Research & Enterprise Accelerator.

£37,005,790

NIHR Guy's and St Thomas' Biomedical Research Centre

NIHR Biomedical Research Centre at Guy's and St Thomas' NHS Foundation Trust and King's College London

Cardiovascular disease, Cutaneous medicine, Genomic medicine, Imaging Sciences, Infection and Immunity, Oral Health, Regenerative Medicine and Cellular Therapy, Transplantation, Women and Children's Health, Clinical Research Facility, Research Platforms, Research Management Infrastructure.

£64,400,267

NIHR Imperial Biomedical Research Centre

NIHR Biomedical Research Centre at Imperial College Healthcare NHS Trust and Imperial College London

Brain Sciences, Cancer, Cardiovascular, Gut Health, Immunology, Infection & AMR, Metabolic Medicine and Endocrinology, Surgery and Technology, Genetics and Genomics, Imaging, Informatics & Biobanking, Molecular Phenomics.

£90,008,746

NIHR Leeds Biomedical Research Centre

NIHR Biomedical Research Centre at Leeds Teaching Hospitals NHS Trust and the University of Leeds

Improving the Treatment of Osteoarthritis, Preventing Disease and Disability in Immune Mediated Inflammatory Diseases.

£6,736,575

NIHR Leicester Biomedical Research Centre

NIHR Biomedical Research Centre at University Hospitals of Leicester NHS Trust and the University of Leicester

Cardiovascular, Lifestyle, Respiratory, Precision Medicine.

£11,591,314

NIHR Manchester Biomedical Research Centre

NIHR Biomedical Research Centre at Central Manchester University Hospitals NHS Foundation Trust and the University of Manchester

Advanced Radiotherapy, Cancer Precision Medicine, Cancer Prevention and Early Detection, Dermatology: Cutaneous Inflammation and Repair, Hearing Health, Respiratory Medicine, Targeted Therapy for better patient outcomes in Musculoskeletal Diseases: Treat Smarter, Biomarker Platforms, Informatics and Data Sciences, Rapid Translation Incubator.

£28,500,000

NIHR Maudsley Biomedical Research Centre

NIHR Biomedical Research Centre at South London and Maudsley NHS Foundation Trust and King's College London

Affective Disorders and Interface with Medicine, Bioinformatics and Statistics, Biomarkers and Genomics, Child and Neurodevelopmental Disorders, Clinical and Population Informatics, Dementia and Related Disorders, Mobile Health, Neuroimaging, Obesity, Pain, Patient and Carer Involvement and Engagement, Psychosis and Neuropsychiatry, Substance Use, Translational Therapeutics, BioSample, Clinical Research Facility, Training and Capacity Development.

£65,977,500

NIHR Moorfields Biomedical Research Centre

NIHR Biomedical Research Centre at Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology

Gene Therapy, Genomic Medicine and Informatics, Inflammation and Immunotherapy, Regenerative Medicine and Pharmaceutics, Visual Assessment and Imaging, Cross-Institutional Collaborative Themes and Training, PPI/E in Research and Clinical Studies Development.

£19,075,000

NIHR Newcastle Biomedical Research Centre

NIHR Biomedical Research Centre at Newcastle upon Tyne Hospitals NHS Foundation Trust and Newcastle University

Dementia, Liver Disease, Musculoskeletal Disease, Neuromuscular Disease, Skin and Oral Disease, Ageing Syndromes, NIHR Newcastle Training School.

£16,208,633

NIHR Nottingham Biomedical Research Centre

NIHR Biomedical Research Centre at Nottingham University Hospitals NHS Trust and the University of Nottingham

Deafness and Hearing Problems, Gastrointestinal and Liver disorders, Mental Health and Technology, Musculoskeletal Disease, Respiratory Disease, MR Imaging.

£23,642,003

NIHR Oxford Biomedical Research Centre

NIHR Biomedical Research Centre at Oxford University Hospitals NHS Foundation Trust and the University of Oxford

Antimicrobial Resistance & Modernising Microbiology, Cardiovascular, Diabetes & Metabolism, Gastroenterology & Mucosal Immunity, Genomic Medicine, Haematology & Stem Cells, Multi-modal Cancer Therapies, Multimorbidity & Long Term Conditions, Musculoskeletal, Neurological Conditions, Obesity, Diet & Lifestyle, Respiratory, Stroke & Vascular Dementia, Surgical Innovation & Evaluation, Technology & Digital Health, Vaccines for Emerging & Endemic Diseases, Clinical Informatics & Big Data, Imaging, Molecular Diagnostics, Partnerships for Health, Wealth & Innovation.

£113,718,800

NIHR Oxford Health Biomedical Research Centre

NIHR Biomedical Research Centre at Oxford Health NHS Foundation Trust and the University of Oxford

Adult Mental Health: Innovation in diagnosis and treatment, Older adults and dementia, Precision Psychological Treatments, Clinical research infrastructure and experimental medicine, Informatics and digital health, Neuroimaging and cognitive neuroscience.

£12,824,900

NIHR Royal Marsden Biomedical Research Centre

NIHR Biomedical Research Centre at The Royal Marsden NHS Foundation Trust and The Institute of Cancer Research

Breast Cancer, Gastrointestinal Cancers, Novel Cancer Therapeutics, Prostate Cancer, Targeted Physical Therapies, Uncommon Cancers, Digital: Capability, Informatics, Big Data, e-Health, Genotypes, Phenotypes and Cancer Evolution.

£43,074,315

NIHR Sheffield Biomedical Research Centre

NIHR Biomedical Research Centre at Sheffield Teaching Hospitals NHS Foundation Trust and the University of Sheffield

Translational Neuroscience for Chronic Neurological Disorders, Advanced Medical, NIHR Sheffield Clinical Research Facility, Predictive (in silico) Medicine.

£4,049,681

NIHR Southampton Biomedical Research Centre

NIHR Biomedical Research Centre at University Hospitals Southampton NHS Foundation Trust and the University of Southampton

Lifecourse Nutrition, Lifestyle and Health, Respiratory and Critical Care, Behavioural Science, Data Science, Microbial Science.

£14,509,067

NIHR University College London Hospitals Biomedical Research Centre

NIHR Biomedical Research Centre at University College London Hospitals NHS Foundation Trust and University College London

Cancer, Cardiovascular Diseases, Deafness and Hearing, Dementia, Inflammation, Immunity & Immunotherapeutics, Mental Health, Neurological Diseases, Obesity, Oral Health & Disease, Education - The BRC Experimental Medicine Academy, Healthcare Engineering & Imaging, Healthcare Informatics, Genomics/Omics, Data Science, Patient & Public Involvement & Engagement/Communications, Therapeutic Innovation Network, Translational Research & Enterprise Accelerator (TREACC).

£111,503,317

Further information

Detailed information about the resources and capabilities of the existing BRCs is available at the UK Experimental Medicine Resource Finder website, or contact the NIHR Office for Clinical Research Infrastructure at nocri@nihr.ac.uk. There is also an NIHR briefing document.