28 February 2021
A treatment for children with a rare form of childhood dementia has made a dramatic difference to their outcomes. The UK arm of the drug trial took place at the NIHR Great Ormond Street Hospital Biomedical Research Centre where today 19 patients receive regular therapy.
12 February 2021
Primary Biliary Cholangitis (PBC), is a life-long rare autoimmune liver disease affecting more than 15,000 people in the UK. Obeticholic acid had shown potential benefit in patients with PBC, however the dose response, safety and efficacy of obeticholic acid was unknown and POISE trial was designed to provide the evidence to these questions.
28 January 2021
Exercise programmes reduce falls among the over 65s by almost a quarter.
27 January 2021
By switching to a virtual model of patient engagement activities, the NIHR successfully supported Pfizer to gather patient input from psoriasis patients on a proposed phase II trial of a new treatment.
26 January 2021
Public engagement from the outset of research helped NIHR researchers develop a website to explain complex and sensitive children’s heart surgery data to the public. The lessons learned led to a best practice guide for researchers involving patients and the public in research.
22 January 2021
Faced with a growing burden of liver disease, researchers at the NIHR Nottingham Biomedical Research Centre reimagined the way that patients could be diagnosed in community settings. Their pathway has been tested and is being taken up by the NHS to the benefit of patients.
20 January 2021
The Impact of trained volunteers on the care of older patients - the Southampton Mealtime Assistance and Mobility Programme is a programme of research which started in 2010. A 12 month feasibility study recruited 29 volunteers who assisted 3911 patients, including 386 who were fed. A subsequent implementation study across four departments demonstrated a cost-effective improvement in quality of care for older inpatients with trained volunteers.
12 January 2021
A blood test has been shown to speed up diagnosis of pre-eclampsia and help determine which women are at most risk of developing severe complications. The test is now widely available across the NHS.
07 January 2021
A new approach to the prevention of challenging behaviour among people with learning disabilities in social care settings has reduced challenging behaviour by two thirds and been rolled out across 800 residential settings.
21 December 2020
Dr Pearse Keane, NIHR Clinician Scientist, is responsible for a research collaboration that has the potential to save sight.
18 December 2020
A non-invasive test for prostate cancer gives a clearer picture of clinically relevant cancer, ruling out cancer in many cases and ensuring more accurate biopsy for those who need it
11 December 2020
An electronic frailty index developed by NIHR-funded researchers has been rolled out in primary care nationally.
04 December 2020
NIHR funded research shows that hospitals with access to a specialist step-down service for their homeless patients saw an 18% reduction in A&E visits.
01 December 2020
Screening women for breast cancer in their forties reduces their chance of dying from breast cancer by 25% in the first 10 years of screening.
26 November 2020
NIHR-funded researchers from the University of Glasgow evaluated the effectiveness of Football Fans in Training (FFIT) - a programme to help football fans lose weight, feel better and live a healthier lifestyle.
20 November 2020
NIHR research finds no evidence of an association between reduced street lighting and night-time road casualties or crime across England and Wales.
10 November 2020
The VOICE study looked at how healthcare professionals could improve their knowledge, confidence and skills for communicating with patients with dementia. It has led to the development of an evidence-based communication skills training course.
05 November 2020
Research supporting the use of skin-to-skin contact to encourage breastfeeding has global impact.
02 November 2020
A set of safety indicators to identify patients at risk of harm from prescribing errors, along with a pharmacist-led IT-based intervention, are reducing clinically important medication errors.
01 November 2020
The aim of the Deciphering Developmental Disorders Study (DDD) is to determine if new high-throughput genetic technologies can determine the cause of developmental disorders, and to facilitate the use of these technologies in the NHS.
30 October 2020
The PET-Neck study showed the value of using PET-CT imaging to avoid unnecessary surgery in patients with head and neck cancer. As a result, PET-CT guided surveillance has now become the standard of care in the NHS, saving over £1,400 per patient over a two year period.
30 October 2020
The HiLo trial has led to changes in national and international guidelines for radioiodine dosage in patients with thyroid cancer, resulting in less toxic and better tolerated treatment that reduces patient side effects and saves money for the NHS.
25 October 2020
NIHR-funded researchers find an 80% reduction in harmful second-hand smoke concentrations following smoking ban in Scotland's prisons.
21 October 2020
The Nursing and Midwifery Incubator is a community of professionals committed to supporting and developing the careers of nurse and midwife researchers.
20 October 2020
New drug helps medical teams make the best decisions to manage critically ill patients.