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Case studies

    shoulder assessment

    Joint funding to tackle shoulder pain

    18 November 2019

    Danielle van der Windt is Professor of Primary Care Epidemiology and Research Director at Keele University’s School for Primary, Community and Social Care. She describes why her research into shoulder pain is so important and how the NIHR-charity co-funding made it happen.

    Hands sorting pills

    PhD students can’t apply for research funding… can they?

    12 November 2019

    Justine Tomlinson is a specialist pharmacist and doctoral training fellow at Leeds Teaching Hospitals NHS Trust and the University of Bradford. She successfully applied for an NIHR Research for Patient Benefit (RfPB) award during her PhD and has shared her advice to encourage other doctoral students to apply.

    Liver and alcohol - alcoholic hepatitis

    STOPAH

    05 November 2019

    Prednisolone (steroid treatment) and pentoxifylline are both recommended for the treatment of severe alcoholic hepatitis and are widely used, but uncertainty remained about their benefits. STOPAH was a randomised double blind trial designed to evaluate the effect of treatment with prednisolone or pentoxifylline in patients with alcoholic hepatitis.

    Four ways research can benefit your career

    Four ways research can benefit your career

    05 November 2019

    We explore four key ways research can benefit your career, featuring testimonies from healthcare professionals who encourage others to follow in their footsteps and take their next step in their research career.

    Bacteria infection

    ARREST

    05 November 2019

    The ARREST trial was designed to assess whether adding rifampicin to standard antibiotic treatment for staphylococcus aureus bacteraemia would improve survival from this infection.

    Andrew Owen case study

    My career path as an intensivist and an academic

    30 October 2019

    Andrew Owen, a dual speciality trainee in anaesthesia and critical care, explains how his research career has progressed as an NIHR Academic Clinical Fellow and an NIHR Clinical Lecturer.

    Why I'm thankful to healthcare staff for giving me the gift of hope

    Finding the balance of a clinical academic research career

    24 October 2019

    A lead clinical physiotherapist provides insight into her path in research - including being the first Allied Health Professional (AHP) in her organisation to be awarded the HEE/NIHR Clinical Doctoral Research Fellowship.

    blood sugar test

    DIPLOMA impact case study

    23 October 2019

    DIPLOMA is a four year programme of work to assess the success of the NHS Healthier You: NHS Diabetes Prevention Programme.

    Alison Finch case study

    My path to research - a cancer nurse's story

    22 October 2019

    A senior nurse shares how she utilised the support of the NIHR’s Research Design Service to focus her application which saw her being awarded a HEE/NIHR Clinical Doctoral Research Fellowship.

    Setting straight six myths about clinical research

    Setting straight six myths about clinical research

    14 October 2019

    We help debunk some common misconceptions about clinical research and explain how it's only by keeping up to date on better treatments and care and improving diagnosis and prevention that we can improve patient care.

    Biobanks and biorepositories present an efficient way of doing research.

    New biobank brings a wealth of new opportunities for UK renal research

    04 October 2019

    Research registries and biobanks present an efficient way of doing research. In the UK the life sciences industry, charities and academia are collaborating to maximise this new approach and open up a wealth of new opportunities to accelerate new advances that will benefit kidney disease patients.

    Dialysis is the process of removing excess water, solutes, and toxins from the blood in people whose kidneys are damaged or have failed.

    Registry-facilitated trial investigates delivery of vitamin D for dialysis patients

    04 October 2019

    Research registries and biobanks present an efficient way of doing research which moves away from the traditional approach of recruiting patients on a study by study basis. In the UK the life sciences industry, charities and academia are collaborating to maximise this new approach and open up a wealth of new opportunities to accelerate new advances that will benefit kidney disease patients.

    skull with bleed on black background

    Interact 2 Impact Case Study

    03 October 2019

    The INTERACT 2 study compared early intensive lowering of blood pressure with existing guidelines.

    human kidney cross section

    SUSPEND Impact Case Study

    03 October 2019

    The SUSPEND study looked at the use of drug therapy in the management of symptomatic ureteric stones in hospitalised adults.

    Novel Trials: Tailor Case Study

    Adopting an adaptive approach to help HIV patients on antiretroviral therapy (cART)

    30 September 2019

    Finding the right dose of any therapy is crucial and adaptive trial designs offer a novel way of finding the most appropriate dose for licensed drugs being repurposed for another indication. Back in 2013, Professor Munir Pirmohamed commenced the TAILoR trial to ascertain the optimum dose of telmisartan to help reduce insulin resistance in HIV-positive patients, and with interesting results.

    Many patients with chronic kidney disease require dialysis treatment.

    Using an adaptive model to trial a new treatment for rare kidney disease

    30 September 2019

    IgA nephropathy is a rare form of kidney disease. There is currently no drug or treatment available but there is hope on the horizon. An adaptive trial model is now being used to investigate a new drug being developed by Novartis, after showing promising results in the lab.

    MND NIV tool

    Tools to improve treatment for motor neurone disease

    10 September 2019

    Dr Esther Hobson is an NIHR Clinical Lecturer in Neurology at the University of Sheffield. She received RfPB funding for a study into non-invasive ventilation for patients with motor neurone disease (MND).