COVID-19 studies jointly funded with UKRI

The following COVID-19 research projects have been awarded funding jointly by the NIHR and UK Research and Innovation (UKRI). Studies identified as 'CRN supported' are part of the portfolio of nationally prioritised Urgent Public Health Studies.

If you are a journalist and are interested in one of the studies below, please contact the NIHR Press Office

Rolling call

NameCRN supportedTypeHost organisationChief InvestigatorAwardStart date
The COVID-19: Clinical Neuroscience Study (COVID-CNS)   Clinical characterization and management  NIHR Health Protection Research Unit for Emerging and Zoonotic Infection and University of Liverpool Dr Benedict Michael and Professor Gerome Breen £2,297,861 October 2020
An analytical framework for Test, Trace and Isolate in the UK: optimising and targeting deployment alongside other measures   Infection prevention and control, including health care workers’ protection The London School of Hygiene & Tropical Medicine Professor Elizabeth Fearon £412,720 October 2020
The impact of COVID-19 and associated social restrictions on people with learning disabilities, their families and social care support workers   Clinical characterization and management  University of Lancashire and University of Warwick Professor Chris Hatton and Professor Richard Hastings £757,294 September 2020
Efficient geostatistical sampling to estimate the fraction of the population recovered from COVID-19   Epidemiological studies University of Warwick Dr Samuel Watson £34,235 September 2020
Impact of COVID-19 Pandemic on Care Home Pathways, Outcomes and Safety of Care   Clinical characterization and management  Lancaster University Professor Jo Knight £252,446 September 2020
Development of a natural transmission model of COVID-19   Infection prevention and control, including health care workers’ protection The London School of Hygiene & Tropical Medicine Dr Stuart Dowall £399,968 September 2020
Controlling COVID19 through enhanced population surveillance and intervention (Con-COV): a platform approach   Infection prevention and control, including health care workers’ protection Swansea University Professor Ronan Lyons £826,353  September 2020
Evidence-Based Supported Digital Intervention for Improving Wellbeing and Health of people living in Care Homes (WHELD) During COVID-19   Clinical characterization and management University of Exeter Professor Clive Ballard £1,219,509 September 2020
Safety and lower airway immunogenicity of two candidate Coronavirus Disease (COVID-19) vaccines administered to the respiratory tract   Candidate vaccines R&D Imperial College London Dr Chris Chiu £579,783 September 2020
ISARIC Clinical Characterisation Protocol UK (CCP-UK) - a companion study for patients with Cancer and COVID-19 (CCP-CANCER-UK)   Clinical characterization and management  University of Liverpool Professor Palmieri and Dr Lance Turtle £342,158 September 2020
Development and manufacture of an improved replication-deficient simian adenoviral vector to prevent COVID-19   Candidate vaccines R&D Vaccitech Ltd Dr Tom Evans £155,000 September 2020
What TRIage model is safest and most effective for the Management of 999 callers with suspected COVID-19? A linked outcome study (TRIM)   Clinical characterization and management Swansea University Professor Alan Watkins £358,400 September 2020
Transmission, pathogenesis and immunogenicity of SARS-CoV-2 in frontline healthcare workers: a national longitudinal cohort of 1320 participants   Infection prevention and control, including health care workers’ protection University of Nottingham Dr Ana M Valdes £719,643 September 2020
AERosolisation And Transmission Of SARS-CoV-2 in Healthcare Settings (AERATOR)   Infection prevention and control, including health care workers’ protection North Bristol NHS Trust Dr Nick Maskell £432,784 September 2020
Investigating SARS-CoV-2 Transmission in North London Communities   Social sciences in the outbreak response
Infection prevention and control, including health care workers’ protection
The London School of Hygiene & Tropical Medicine Dr Michael Marks £249,232 September 2020
The contribution of occupational exposures to risk of COVID-19 and approaches to control among healthcare workers (COPE-Birmingham)   Infection prevention and control, including health care workers’ protection University of Birmingham Professor Peymané Adab £441,309 September 2020
Transmission of COVID-19 in Kids (TraCK) Yes Infection prevention and control, including health care workers’ protection Imperial College London Professor Shiranee Sriskandan £267,388 September 2020
Nosocomial transmission of SARS-CoV-2   Infection prevention and control, including health care workers’ protection The London School of Hygiene & Tropical Medicine Dr Gwen Knight £127,027 September 2020
Suppressing SARS-CoV-2 transmission in public spaces through surface engineering   Infection prevention and control, including health care workers’ protection University of St Andrews  Professor Peter Wahl £270,977 September 2020
COVID-19 Mapping and Mitigation in Schools (CoMMinS)   Infection prevention and control, including health care workers’ protection University of Bristol Professor Caroline Relton £2,795,303 September 2020
Humoral Immune Correlates for COVID-19 (HICC): defining protective responses and critical readouts for clinical trials of vaccines and therapeutics Yes Virus: natural history, transmission and diagnostics University of Cambridge Professor Wilhelm Schwaeble £1,522,681 August 2020
The UK Coronavirus Immunology Consortium (UK-CIC): a UK underpinning platform to study immunology and immunopathology of COVID-19 Yes Virus: natural history, transmission and diagnostics University of Birmingham Professor Paul Moss £6,500,000 August 2020
Inflammation in Covid-19: Exploration of Critical Aspects of Pathogenesis (ICECAP)   Virus: natural history, transmission and diagnostics University of Edinburgh Christopher D. Lucas £393,795 August 2020
Liverpool COVID-19 Drug Interactions   Clinical characterization and management University of Liverpool Prof Saye Khoo £65,645 August 2020
The production and application of SARS-CoV-2 reverse genetic systems to facilitate vaccine development and biosafe drug discovery platforms   Candidate vaccines R&D University of Bristol Dr Andrew Davidson £204,326 August 2020
Modelling the dynamics of viral load to reveal mechanisms of protection in COVID-19   Virus: natural history, transmission and diagnostics Imperial College London Dr Aubrey Cunnington £194,553 August 2020
COVID-19: Assessing the vulnerability of the fetus to SARS-CoV2 infection across development   Clinical characterization and management UCL Dr Mattia Gerli £25,000 August 2020
Demographic, multi-morbidity and genetic impact on myocardial involvement and its recovery from COVID-19: the COVID-HEART study Yes Epidemiological studies University of Leeds Professor John P Greenwood £75,096 August 2020
Prognostic models for COVID-19 to support risk stratification in secondary care   Epidemiological studies
Clinical characterization and management
University of Birmingham Dr Nicola Adderley £102,474 August 2020
Longitudinal immunological and multi-omic profiling of haemodialysis patients   Clinical characterization and management  Imperial College London Dr James Peters £584,188 August 2020
A rapid realist review of community pharmacy support for the public health agenda during the COVID-19 pandemic and future health emergencies   Epidemiological studies Aston University Dr Ian Maidment £85,442 July 2020
Ensuring that COVID-19 trials consider ethnicity: the INCLUDE Ethnicity Framework for randomised trials   Clinical characterization and management University of Aberdeen Prof Shaun Treweek £15,051  July 2020
United Kingdom Research Study into Ethnicity And COVID-19 outcomes in Healthcare workers (UK-REACH) Yes Infection prevention and control, including health care workers’ protection University of Leicester Dr Aarti Pareek £2,128,823  July 2020
Ethnicity and COVID-19: investigating the determinants of excess risk in UK Biobank   Epidemiological studies University of Leicester Prof Thomas Yates £125,992  July 2020
Developing and Delivering targeted SARS-CoV-2 (COVID-19) health interventions to Black, Asian and Minority Ethnic (BAME) communities living in the UK   Infection prevention and control, including health care workers’ protection Royal Surrey County Hospital NHS Foundation Trust Professor Aftab Ala £370,734  July 2020
Quantifying the association between COVID-19, ethnicity and mortality: A cohort study across three UK national databases   Epidemiological studies University of Oxford Professor Julia Hippisley-Cox £327,488  July 2020
Investigating incidence, severity and risk factors for COVID-19 in BAME and Migrant groups to inform public health action   Epidemiological studies UCL Dr Robert Aldridge £1,396,357  July 2020
COVID-NURSE. The development, testing and evaluation of a COVID-19 fundamental nursing care protocol: a randomised controlled trial   Clinical characterization and management
Infection prevention and control, including health care workers’ protection
 University of Exeter Professor David Richards £430,470  July 2020
Post-hospitalisation COVID-19 study: a national consortium to understand and improve long-term health outcomes (PHOSP-COVID) Yes Epidemiological studies
Clinical characterization and management 
University of Leicester Professor Chris Brightling £8,400,000 June 2020
COVID-19 National DiagnOstic Research and Evaluation Platform (CONDOR) Yes Virus: natural history, transmission and diagnostics University of Oxford and University of Manchester Professor Gail Hayward and Professor Richard Body £1,300,000 June 2020
Urgent research and surveillance on COVID-19 using the new OpenSAFELY secure platform across 55 million patients' full linked primary care records   Epidemiological studies University of Oxford Dr Ben Goldacre £1,350,000 May 2020
COVID-19: Mathematical modeling and adaptive control to inform real time decision making for the COVID-19 pandemic at the local, regional and national scale Yes Epidemiological studies University of Warwick Dr Michael Tildesley £241,178 May 2020
Rapid evaluation of the COVID-19 pandemic response in palliative and end of life care: national delivery, workforce and symptom management (CovPall)   Clinical characterization and management King's College London Professor Irene Higginson £278,619 May 2020

 

Call 2

NameCRN supportedTypeHost organisationChief InvestigatorAwardStart date
A protease activity profiling strategy to inhibit cell-to-cell transmission of SARS-CoV-2   Virus: natural history, transmission and diagnostics University of Oxford Dr Sumana Sanyal £213,137 April 2020
Understanding environmental and airborne routes of transmission   Virus: natural history, transmission and diagnostics Public Health England Allan Bennett £337,435 April 2020
Understanding the dynamics and drivers of the COVID-2019 epidemic using real-time outbreak analytics   Epidemiological studies London School of Hygiene and Tropical Medicine Dr John Edmunds £492,766 April 2020
nCoV: A global registry of women affected by COVID-19 in pregnancy, understanding natural history to guide treatment and prevention Yes Virus: natural history, transmission and diagnostics
Clinical characterization and management
Imperial College London Professor Christoph Lees £253,257 April 2020
Spatial heterogeneity in transmission and the impact of interventions: a mathematical modelling approach   Epidemiological studies University of Exeter Dr Leon Danon £220,403 April 2020
Rapid co-design, implementation and evaluation of a digital behaviour change intervention to improve hand hygiene and limit spread of the COVID-19 outbreak   Social sciences in the outbreak response.
Infection prevention and control, including health care workers’ protection
University of Southampton Professor Lucy Yardley £249,056 April 2020
nCoV: Understanding the dynamics of policy development and healthcare worker behaviour in the UK during the Covid-19 public health emergency   Social sciences in the outbreak response University of Liverpool Professor Sally Sheard £294,488 April 2020
Virus Watch: Understanding community incidence, symptom profiles, and transmission of COVID-19 in relation to population movement and behaviour Yes Epidemiological studies
Clinical characterization and management
University College London Professor Andrew Hayward £3,248,052 April 2020
A mixed-methods evaluation of advice on isolation and health-seeking to contain transmission   Social sciences in the outbreak response
Infection prevention and control, including health care workers’ protection
Public Health England Professor Isabel Oliver £413,418 April 2020
Estimating severity from multiple data sources using Bayesian evidence synthesis   Epidemiological studies
Clinical characterization and management
University of Cambridge Dr Anne Presanis £180,599 April 2020
Early Assessment of COVID-19 epidemiology and Vaccine/anti-viral Effectiveness (EAVE II)   Epidemiological studies
Clinical characterization and management
University of Edinburgh Professor Aziz Sheikh £372,229 April 2020
Coronavirus STORY (Serum Testing of Representative Youngsters) Yes Epidemiological studies University of Oxford Professor Matthew Snape £573,070 March 2020
nCoV: Serological detection of past SARS-CoV-2 infection by non-invasive sampling for field epidemiology and quantitative antibody detection   Virus: natural history, transmission and diagnostics
Epidemiological studies
Imperial College London Professor Richard Tedder £429,983 April 2020
Platform Randomised trial of INterventions against COVID-19 In older peoPLE (PRINCIPLE) Yes Virus: natural history, transmission and diagnostics University of Oxford Professor Christopher Butler £1,706,579 April 2020
Development of an NHP model of infection and ADE with COVID-19 (SARS-CoV-2)   Virus: natural history, transmission and diagnostics Public Health England Professor Miles Carroll £445,738 April 2020
Healthcare Workers: an in depth virological analysis and behavioural study during the outbreak   Candidate vaccines R&D University College London Dr Eleni Nastouli £1,463,790 April 2020
Understanding Chinese government containment measures and their societal impacts   Virus: natural history, transmission and diagnostics
Clinical characterization and management
University of Glasgow Professor Jane Duckett £333,963 April 2020
Gig workers: unsung heroes and a strategic role in the UK national response to the COVID-19 pandemic   Virus: natural history, transmission and diagnostics University of Manchester Professor Martie van Tongeren £337,913 April 2020
Strengthening & Accelerating the Global Research Response to COVID-19 by Sharing Methods and Knowledge Between Countries, Networks and Organisations   Virus: natural history, transmission and diagnostics University of Oxford Professor Trudie Lang £299,860 April 2020

 

Call 1

NameCRN supportedTypeHost organisationChief InvestigatorAwardStart date
nCoV: Rapid Clinical Development of ChAdOx1 nCoV-19   Candidate vaccines R&D University of Oxford Professor Sarah Gilbert £2,174,848 March 2020
COVID-19 multi-arm, multi stage adaptive clinical trial (CoV-MAMS) Yes Candidate therapeutics R&D University of Oxford Professor Peter Horby £2,106,034 March 2020
Repurposing FDA-Approved Drugs for Treatment of 2019-nCoV-induced Disease Yes Candidate therapeutics R&D Queen's University Belfast Professor Ultan Power £295,625 March 2020
COVID-19: Enabling availability for clinical use of 1 million doses of adenovirus-vectored COVID-19 vaccine by summer 2020 Yes Candidate vaccines R&D University of Oxford Dr Alexander Douglas £411,388 March 2020
ISARIC - Coronavirus Clinical Characterisation Consortium (ISARIC-4C)   Clinical characterization and management University of Edinburgh Dr Kenneth Baillie £4,908,946 March 2020
nCoV: Developing CoV-bnMABs for therapy of highly pathogenic coronaviruses including
SARS-CoV-2
Yes Candidate therapeutics R&D Imperial College London Professor Xiao-Ning Xu £614,426 March 2020
saRNA SARS-CoV-2 vaccine   Virus: natural history, transmission and diagnostics Imperial College London Professor Robin Shattock £1,724,708 April 2020
Development of an ovine polyclonal immunoglobulin therapy against COVID-19   Virus: natural history, transmission and diagnostics
Epidemiological Studies
Public Health England Dr Stuart Dowall £445,720 April 2020