Study Detail

C-MORE Capturing MultiORgan Effects of COVID-19

Assessing the effects of Coronavirus Disease (COVID-19) on multiple organ systems and impact on quality of life, functional capacity and mental health

Status: Open

Type: Observational


Sponsor: University of Oxford

CI: Professor Stefan Neubauer

IRAS-Number: 282608

CPMS-ID: 45642

Approval Date: 04 June 2020


The purpose of this study is to understand the effects of COVID-19 on the health of the lungs, heart, brain, liver and kidney and assess its effects on the quality of life, mental health and exercise capacity of affected individuals over a period of 12 months after the infection and compare these with those of people who have not had COVID-19. We would like to study up to 616 patients who have been infected with SARS-CoV-2, (the virus that causes COVID-19) and 62 people who have not been infected. We will use the control group as a benchmark to compare against the results of the other group. Participants will be invited to attend up to 3 visits around three, six and twelve months after the infection. Controls who have not shown COVID-19 symptoms will attend only one visit. The visits will include magnetic resonance imaging of the lungs, heart, brain, liver and kidney as well as assessments of breathing, exercise capacity and mental health.

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