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2020 NIHR ACF PES Cambridge Platform Science and Bioinformatics



2020 NIHR Academic Clinical Fellowship in Priority Research Themes

HEE Local Office: East of England
Medical School: University of Cambridge
Research Theme: Platform Science and Bioinformatics
Specialty Options: Chemical Pathology or Histopathology or Public Health Medicine

Plain English Summary

This training post either in chemical pathology, histopathology or public health makes use of the excellent environment in Cambridge to provide training in the use of novel measurement approaches to investigate the molecular basis of disease. By combining extensive genetic data with measurement of small molecules and proteins in the same individuals, the research teams aim to identify key pathways that are linked to multiple diseases and to determine whether these links are related to the cause of those diseases. This information is valuable to the development of medicines that can intervene in these pathways.

An Academic Clinical Fellowship (ACF) in Chemical Pathology would be part of the training programme based in Addenbrooke’s Hospital which is uniquely placed to be able to offer exceptional opportunities to aspiring clinical academics, as there are rich collaborative relationships with clinical academics in all disciplines in the chemical pathology curriculum, including diabetes, renal tubular disorders, lipid disorders, obesity, inherited metabolic disease and metabolic bone disease.

An ACF in Histopathology would be based in the University Division of Cellular and Molecular Pathology, integrated with the NHS Department of Histopathology, Addenbrooke’s Hospital. This is one of the largest clinical histopathology laboratories in the country, providing research opportunities in all aspects of general surgical pathology, transplantation and renal pathology, breast, dermatology, gastro-intestinal, haematological, gynaecological and paediatric pathology as well as gynaecological and non-gynaecological cytology.

An ACF in Public Health would be part of the Cambridge Public Health training programme. The service element of the ACF training would be performed through the East of England public health scheme and the academic element at the University of Cambridge Institute of Public Health, either based at the MRC Epidemiology Unit or the Department of Public Health and Primary Care, which have assembled multi-dimensional population cohorts with detailed genomic, intermediate biochemical, health-related behaviour and health outcome data.