HTA Funding Committee (General)
Day 1 - 12 July 2022
Venue
- Danubius Hotel - Regents Park, London
Present Members
- Julia Brown (Chair)
- Rupert Pearse (Deputy Chair)
- Andrew Farmer (Programme Director)
- Ashley Agus
- Hashim Ahmed
- Laura Coates (Committee Member Development Scheme Participant)
- Matthew Costa
- Janet Deane (Committee Member Development Scheme Participant)
- Jo Dumville
- Caroline Free
- Simon Gates
- David Green (Public Committee Member)
- Khalida Ismail
- David Keene
- Asma Khalil
- Stephanie MacNeill
- Stuart McIntosh
- Hema Mistry
- Matthew Moore (Public Committee Member)
- Craig Ramsay
- Athanasios Saratzis
- Marta Soares
- Sara Twaddle
- Dawn-Marie Walker
Secretariat
- Simon Fraser (Consultant Advisor)
- James Morris (Consultant Advisor)
- Helen Payne (Senior Research Manager)
- Cristina Lujan Barroso (Research Manager)
- Louisa Saunders (Assistant Research Manager)
Apologies
- Nick Francis
- Kerenza Hood
- Mark Peters
- Joanna Thompson-Coon
Observers
- None
Quoracy Information
- Voting members: 25 (Emergency Quoracy = 18 = 66%)
- Voting members present on Day 1: 21 (84 %)
Stage 2 proposals
21/558 NIHR James Lind Alliance Priority Setting Partnerships Rolling Call
NIHR151230 - A randomised controlled trial assessing the clinical and cost-effectiveness of Endovascular vs. Open revascularisation in severe oCClusive aorto-iliac disease. The EVOCC trial. (Athanasios Saratzis)
Chair: Julia Brown
Conflicts: Athanasios Saratzis, Hashim Ahmed
Decision: Programme Oversight Committee to consider fund with changes
NIHR150958 - PROTECT PRegnancy Outcomes using continuous glucose monitoring TEChnology in pregnant women with Type 2 diabetes: A multicentre randomised controlled trial of the clinical and cost-effectiveness of using continuous glucose monitoring in pregnant women with type 2 diabetes (Helen Murphy)
Chair: Rupert Pearse
Conflicts: Janet Deane, Julia Brown, Khalida Ismail
Arrived at the meeting: Matthew Costa
Decision: Resubmission
21/555 Health Technology Assessment Programme Researcher-led (evidence synthesis)
NIHR151853 - Diagnostic strategies for suspected acute aortic syndrome (AAS): Systematic review, meta-analysis, decision-analytic modelling, and value of information analysis (Steve Goodacre)
Chair: Rupert Pearse
Conflicts: David Keene
Decision: Programme Oversight Committee to consider fund with changes
Stage 1 Proposals
22/2 HTA Researcher-led call Evidence Synthesis
NIHR153187 - Treatment options for women with heavy menstrual bleeding: A comprehensive systematic review, network meta-analysis, and health economic assessment. (Bassel Hamameeh Al Wattar)
Chair: Julia Brown
Conflicts: Rupert Pearse, Athanasios Saratzis
Decision: Shortlist
NIHR153148 – Pathways of care for advanced osteoarthritis of the knee in younger adults: systematic review and lifetime assessment of quality of life and cost consequences (Yen-Fu Chen)
Chair: Julia Brown
Conflicts: Andrew Farmer, Simon Gates, Laura Coates, David Keene, Hema Mistry
Decision: Decline
22/1 HTA Researcher-led call Primary Research
NIHR152188 - Cooling in mild encephalopathy (COMET) trial (Sudhin Thayyil)
Chair: Julia Brown
Conflicts: Andrew Farmer, Hashim Ahmed, David Keene, Hema Mistry, Dawn-Marie Walker, Khalida Ismail
Left the meeting: Matthew Moore
Decision: Shortlist
NIHR152520 - Surgery or embolisATIoN for bleeding haemorrhoids (SATIN ) (Clare Bent)
Chair: Julia Brown
Conflicts: Simon Fraser, James Morris, Andrew Farmer, Marta Soares
Arrived at the meeting: Matthew Moore
Decision: Decline
NIHR153127 - Skin cancer Prevention with Nicotinamide in Transplant Recipients (SPRINTR-UK). Nicotinamide chemoprevention for keratinocyte carcinoma in solid organ transplant recipients: a multi-centre, pragmatic randomised trial (Rubeta Matin)
Chair: Julia Brown
Conflicts: Andrew Farmer, Rupert Pearse, Stephanie MacNeill, Laura Coates, Hema Mistry, Janet Deane
Decision: Decline
NIHR153085 – EXTRACTion Or Replacement of redundant/malfunctioning leads: EXTRACTOR Study (Christopher Rinaldi)
Chair: Julia Brown
Conflicts: Khalida Ismail
Left the meeting: Matthew Moore
Decision: Decline
NIHR152069 - A multi-centre randomised controlled trial of standard care versus an accelerated care pathway after cardiac surgery (FARSTER-care). (Dumbor Ngaage)
Chair: Julia Brown
Conflicts: Jo Dumville, Marta Soares
Decision: Shortlist
22/4 NIHR James Lind Alliance Priority Setting Partnerships Rolling Call
NIHR153258 - The clinical and cost-effectiveness of desogestrel for problem bleeding on the etonogestrel contraceptive implant: a randomised placebo-controlled trial with economic and acceptability evaluations (DEBI) (Kate Walker)
Chair: Rupert Pearse
Conflicts: Andrew Farmer, Caroline Free, Asma Khalil, Hema Mistry
Decision: Resubmission
NIHR153139 - Randomised Evaluation of rehabilitation after ACute proximal Humerus fracture (the REACH trial) (David Keene)
Chair: Julia Brown
Conflicts: Andrew Farmer, Matthew Costa, Jo Dumville, David Keene, Stephanie MacNeill, Laura Coates, Hema Mistry, Marta Soares
Decision: Shortlist
22/12 The development and evaluation of predictive algorithms using Artificial Intelligence (AI) - HTA
NIHR152979 - Artificial intelligence decision support software (ArtiQ-PFT) during diagnostic pulmonary function testing - a mixed methods cluster randomised controlled trial (William Man)
Chair: Julia Brown
Conflicts: Hashim Ahmed, Khalida Ismail
Decision: Decline
NIHR153364 - StratCare Trial 2: Evaluating the clinical and cost-effectiveness of AI-driven stratified care for depression (Jaime Delgadillo)
Chair: Julia Brown
Conflicts: None
Decision: Resubmission
Day 2 - 13 July 2022
Venue
- Danubius Hotel - Regents Park, London
Present Members
- Julia Brown (Chair)
- Rupert Pearse (Deputy Chair)
- Andrew Farmer (Programme Director)
- Ashley Agus
- Hashim Ahmed
- Laura Coates (Committee Member Development Scheme Participant)
- Matthew Costa
- Janet Deane (Committee Member Development Scheme Participant)
- Jo Dumville
- Caroline Free
- Simon Gates
- David Green (Public Committee Member)
- Khalida Ismail
- David Keene
- Stephanie MacNeill
- Stuart McIntosh
- Hema Mistry
- Matthew Moore (Public Committee Member)
- Mark Peters
- Craig Ramsay
- Athanasios Saratzis
- Marta Soares
- Sara Twaddle
- Dawn-Marie Walker
Secretariat
- Simon Fraser (Consultant Advisor)
- Helen Payne (Senior Research Manager)
- Cristina Lujan Barroso (Research Manager)
- Louisa Saunders (Assistant Research Manager)
Apologies
- Nick Francis
- Kerenza Hood
- Asma Khalil
- Joanna Thompson-Coon
Observers
- None
Quoracy Information
- Voting members: 25 (Emergency Quoracy = 18 = 66%)
- Voting members present on Day 2: 21 (84%)
21/592 Hypertension in pregnancy
NIHR152762 - STARshiP: Screen and Treat with Aspirin to Reduce Pre-eclampsia (Jenny Myers)
Chair: Rupert Pearse
Conflicts: Andrew Farmer, Janet Deane, Hema Mistry, Julia Brown, Khalida Ismail
Decision: Shortlist
22/7 Delivering a Sustainable Health and Care System
NIHR153188 - EVERGREEN Trial - EVidence-based Evaluation of Re-usable Gowns and dRapEs in EmergeNcy laparotomy (Aaron Quyn)
Chair: Rupert Pearse
Conflicts: Julia Brown
Arrived at the meeting: Matthew Moore
Decision: Decline
22/3 NIHR NICE Rolling Call
NIHR152027 - A randomised controlled trial of regular MRI scans compared to standard care in patients with prostate cancer managed using active surveillance (Hashim Ahmed)
Chair: Julia Brown
Conflicts: Hashim Ahmed, Janet Deane, Stephanie MacNeill, Marta Soares, Khalida Ismail
Decision: Shortlist
NIHR152322 - Big Toe OstEoarthritis (Big TOE) Trial (Michael Backhouse)
Chair: Rupert Pearse
Conflicts: Simon Gates, David Keene, Hema Mistry, Dawn-Marie Walker, Julia Brown
Left the meeting: Matthew Moore
Decision: Decline waive 12 months
NIHR152294 - PREhabilitation for PAtients undergOing open abdominal aoRTic Aneurysm repair awaiting open elective repair (PREP-AORTA): a multicentre pragmatic randomised controlled trial. (Amy Harwood)
Chair: Julia Brown
Conflicts: Rupert Pearse, Simon Gates, David Keene, Hema Mistry, Athanasios Saratzis
Decision: Decline
NIHR153059 - A novel reliever strategy for children with asthma: CARE-UK: Children’s Anti-Inflammatory Reliever Study (Louise Fleming)
Chair: Julia Brown
Conflicts: Simon Fraser, Hashim Ahmed, Rupert Pearse, Craig Ramsay, Dawn-Marie Walker
Decision: Shortlist
NIHR152262 - Breathing Assistance in CHildren with bronchiolitis (BACHb): a two-stratum multicentre open-label randomised trial of respiratory support in infants with acute bronchiolitis (Padmanabhan Ramnarayan)
Chair: Rupert Pearse
Conflicts: Andrew Farmer, Hashim Ahmed, Janet Deane, Mark Peters, Craig Ramsay, Hema Mistry
Decision: Shortlist
NIHR152845 - SORTED Surgery Or Rehabilitation for Traumatic shouldEr Dislocations (Stephen Gwilym)
Chair: Julia Brown
Conflicts: Andrew Farmer, Matthew Costa, Stephanie MacNeill, David Keene, Laura Coates, Hema Mistry
Arrived at the meeting: Matthew Moore
Decision: Shortlist
NIHR152876 – Are advanced airway protection, secretions removal and cuff pressure maintenance systems effective for mechanically ventilated patients on intensive care? (Gareth Kitchen)
Chair: Julia Brown
Conflicts: Ashley Agus, Janet Deane, Jo Dumville, Simon Gates, Hema Mistry, Stuart McIntosh
Decision: Decline waive the 12 months rule
NIHR153226 – Influence of Direct Superior or Posterior Approach for Total Hip Arthroplasty (InDePTH): A Randomised Controlled Superiority Trial with a Participatory Research Approach (Nick Ohly)
Chair: Julia Brown
Conflicts: None
Decision: Decline
NIHR152516 - ICS-RECODE: Predictors of treatment REsponse to inhaled corticosteroids (ICS) in COPD: randomised COntrolled trials individual participant Data re-Evaluation. (Alexander Mathioudakis)
Chair: Julia Brown
Conflicts: Jo Dumville, Marta Soares
Decision: Shortlist
22/1 HTA Researcher-led call Primary Research
NIHR152157 - OVATION: a randomised comparison of oral and intravenous arsenic trioxide in newly-diagnosed acute promyelocytic leukaemia (Steven Knapper)
Chair: Julia Brown
Conflicts: Hema Mistry
Left the meeting: Matthew Moore
Decision: Shortlist