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HTA Funding Committee Public Outcomes Table 22-23 January 2019

 

Contents

NIHR HTA Funding Committee - 22-23 January 2019

Stage 2 Applications

The following Stage 2 applications have been supported by the HTA Prioritisation Group, subject to certain conditions.

Project Reference

Applicant

 Institution

 Project Title

Commissioned

NIHR127849

Dr Michael Whitehouse

University of Bristol

A Randomised Controlled Trial of Scaffold InSertion and MIcrofracture Compared to Microfracture Alone for the Treatment of Chondral or Osteochondral Defects of the Knee: The SISMIC Study

NIHR127850

Professor Barnaby Reeves

University of Bristol

Surgical interventions to treat severe pressure sores (SIPS)

NIHR127550

Professor Opinder Sahota

Nottingham University Hospitals NHS Trust

The BLAST OFF (Bisphosphonate aLternAtive regimenS for the prevenTion of Osteoporotic Fragility Fractures) Study

NIHR127468

Professor Mehul Dattani

UCL Institute of Child Health

The GHD reversal study

 NIHR127385  Dr James Frith  Newcastle University  A comparison of fludrocortisone, midodrine or usual care to treat orthostatic hypotension – a multi-arm multi-stage randomised controlled trial
 NIHR127489  Associate-Professor Oliver Rivero-Arias  University of Oxford  Valuing the benefits and harms of antenatal and newborn screening programmes in health economic assessments
 NIHR127674  Associate-Professor Daniel Perry  University of Oxford  CRAFFT – Children’s Radius Acute Fracture Fixation Trial. A multi-centre prospective randomized trial of surgical reduction versus non-surgical casting for displaced distal radius fractures in children.
 NIHR127810  Professor Barry Wright  The University of York  Routinely used interventions for improving attachment in infants and young children: an updated systematic review and comprehensive UK survey
 NIHR127755  Professor Oliver Howes  Institute of Psychiatry, Psychology & Neuroscience, King's College London  ATLANTIS: AnTiconvuLsant AugmeNtation Trial In Schizophrenia
 NIHR127337  Professor Dheeraj Rai  Avon and Wiltshire Mental Health NHS Partnership Trust  A multicentre double-blind placebo-controlled randomised trial of SerTRaline for AnxieTy in adults with Autism (STRATA)

 Further information on the above projects will be provided on the HTA website once the project has started.

Stage 1 Applications

The following Stage 1 applications have been shortlisted to submit a Stage 2 application for consideration by the NIHR HTA Funding Committee at its next meeting.

 Project Reference Applicant Institution Project Title
Commissioned
 NIHR128490 Professor Richard Grieve  London School of Hygiene & Tropical Medicine PERsonalised Medicine for Intensification of Treatment (PERMIT): the case of type 2 Diabetes Mellitus
 NIHR128263  Professor Mark Kilby University of Birmingham SLIGHT: SeLectIve fetal GrowtH restriction in monochorionic Twins: is a randomised controlled trial of active intervention versus expectant management feasible?
 NIHR128596  Professor Asma Khalil St George's, University of London FERN: Intervention or Expectant Management for Early Onset Selective Fetal Growth Restriction in Monochorionic Twin Pregnancy
 NIHR128043 Professor Jonathan Rees The Chancellor Masters and Scholars of the University of Oxford Partial Rotator Cuff Tear Repair Trial (PRO CURE Trial)
 NIHR128604  Dr David Ellard University of Warwick Partial ROTator Cuff Tears Management (PROTeCT-M): A Randomised Controlled Trial
 NIHR128399 Associate-Professor Xavier Griffin University of Oxford World Hip Trauma Evaluation - FRUITI: Fix or Replace Undisplaced Intracapsular fractures Trial of Interventions
 NIHR128553  Mr Gorav Datta University Hospital Southampton NHS Foundation Trust Fix Or REplace Surgery In General Hip Trauma (FORESIGHT) Trial
 NIHR128550  Professor Glynis Murphy  University of Kent RCT of group CBT for men with intellectual and/or developmental disabilities and harmful sexual behaviour: the HaSB-IDD trial
 NIHR128128 Professor Elizabeth Hughes University of Leeds The RECO study: Realist Evaluation of service models and systems for CO- existing mental health and substance use conditions.
 NIHR128472 Professor Chris Hollis University of Nottingham  Stimulant Medication for ADHD and Tics - Understanding Response versus Non-stimulants (SATURN study): a randomised trial of the clinical and cost-effectiveness of methylphenidate versus guanfacine for ADHD in children and young people with a co-existing tic disorder
 NIHR128109 Professor Simon Conroy University of Leicester Identification of older patients likely to require enhanced care on discharge from hospital 
NIHR128625 Dr Jo Dumville  The University of Manchester  Adjustable hook-and-loop-fastened compression systems for the treatment of venous leg ulcers
NIHR128462 Dr Prakash Saha  King's College London Velcro wRAp DevIces versus standard Compression bandaging for venous Leg ulcEration: the RADICLE trial.
NIHR128617 Mr Nick Lansdale  Royal Manchester Children's Hospital  Timing of Stoma Closure in Neonates (ToSCiN) Study 
NIHR128623  Dr Emmanuelle Peters King's College London Multisite Randomised Controlled Trial of Trauma-Focused Cognitive Behaviour Therapy for psychosis (TF-CBTp) to reduce post-traumatic stress disorder (PTSD) symptoms in patients with co-morbid PTSD and psychosis, compared to usual treatment: the TRUST (TRaUma and pSychosis Therapy) trial