Internet Explorer is no longer supported by Microsoft. To browse the NIHR site please use a modern, secure browser like Google Chrome, Mozilla Firefox, or Microsoft Edge.

Invention for Innovation - Connect Call 3 Stage 1 Minutes

Contents

Published: 07 October 2019

Version: 1

Print this document

Minutes of the Invention for Innovation (i4i) programme Sub-Committee meeting to discuss i4i Connect 3 Stage 1 (Expression of Interest) applications.

Date and location

Meeting held on 24 September 2019 at LGC Ltd, Grange House, 15 Church Street, Twickenham TW1 3NL.

In attendance

NIHR CCF i4i Secretariat

Mr Martin Hunt (Programme Director)

Professor Paul Sibbons (Chair)

Dr Ruth Nebauer (Assistant Director)

Dr Andrew Barber

Dr Emma Blamont

Mr Freddy Guenemi

Dr Chris Hill

Dr Caterina Lombardo

Mrs Paula Milton

Dr Ian Newington

Dr Raffaella Roncone

Sandra Nwokeoha

Edwin Tucker

Apologies

Dr Katherine Horner

Stage 1 applications invited to submit to Stage 2

The following Stage 1 applications were discussed and invited to submit to Stage 2 (applications sorted by highest average review score in descending order).

 

NIHR201250: FastWCE: Computer vision for the automated assessment of Crohn's Disease severity in Wireless Capsule Endoscopy

Outcome: Invited to submit stage 2 application

 

NIHR201253: SurePulse - heart rate monitoring for newborn babies

Outcome: Invited to submit stage 2 application

 

NIHR201270: Development of Clinical Prototype Novel Dry Powder Inhaler Device

Outcome: Invited to submit stage 2 application

 

NIHR201273: Decision support system for minimally invasive cerebral stenting surgeries

Outcome: Invited to submit stage 2 application

 

NIHR201283: Mental health therapy Provision, Research & Outcomes via Virtual Environments (IMPROVE)

Outcome: Invited to submit stage 2 application

 

NIHR201181: ViscoTurf - Preventing secondary diabetic foot ulceration

Outcome: Invited to submit stage 2 application

 

NIHR201204: Enhancing Children's mental resilience through Embers the    Digital Dragon

Outcome: Invited to submit stage 2 application

 

NIHR201213: Wearable Brain Function Monitor

Outcome: Invited to submit stage 2 application

 

NIHR201230: Developing an innovative implanted resection cavity electrotherapy device for the treatment of Glioblastoma Multiforme (GBM).

Outcome: Invited to submit stage 2 application

 

NIHR201254: Prostate Liquid Biopsy Test for Risk Stratification of Prostate Cancer, preparation for CE marking.

Outcome: Invited to submit stage 2 application

 

NIHR201282: Further development of and evidence generation for a precision dosing tool for optimising chemotherapy dosing in advanced prostate cancer

Outcome: Invited to submit stage 2 application

 

NIHR201292: NeuroPlatform: A novel digital therapy platform aiding the transition from NHS to home for stroke survivors by making rehabilitation enjoyable and affordable.

Outcome: Invited to submit stage 2 application

 

NIHR201184: Neuroimaging headband design and build: low-cost, non-invasive, portable medical device for determination of personalised dementia risk      

Outcome: Invited to submit stage 2 application

 

NIHR201217: Enable patients to become players with Playphysio

Outcome: Invited to submit stage 2 application

 

NIHR201246: Personalised digital therapy and self-care support for the management of Irritable Bowel Syndrome: Zemedy-AI

Outcome: Invited to submit stage 2 application

 

NIHR201260: Physio Exerciser Smartphone App for enhanced patient rehabilitation following musculoskeletal injury

Outcome: Invited to submit stage 2 application

 

NIHR201265: Establishing the efficacy of smart glasses for patients with central vision loss

Outcome: Invited to submit stage 2 application

 

NIHR201281: Transforming management of advanced prostate cancer: Increasing clinical productivity and capacity and empowering men through digital health

Outcome: Invited to submit stage 2 application

 

NIHR201183: Ambra1 STRatification of HPV positive Oropharyngeal Squamous      cell carcinoma for DE- escalation Treatment regimens (ASTRO-DET)

Outcome: Invited to submit stage 2 application

 

NIHR201190: Bridgit home support and integrated social care provision.

Outcome: Invited to submit stage 2 application

 

NIHR201203:The Development of Exergaming for Spinal Cord Rehabilitation

Outcome: Invited to submit stage 2 application

 

NIHR201214: BioPhotonics for Medical Devices

Outcome: Invited to submit stage 2 application

 

NIHR201242: Clinical verification study for further development of a real-time, remote and wearable hydration monitoring system.

Outcome:  Invited to submit stage 2 application

 

NIHR201285: IoT Automated Quantification of Muscular Rigidity and Underlying Neural Signals in Parkinson’s Disease (PD)

Outcome: Invited to submit stage 2 application

 

NIHR201290: Improving Myocardial Perfusion Imaging Processing for the Management of Patients with Cardiovascular Disease using Machine Learning.

Outcome: Invited to submit stage 2 application

 

NIHR201295: Enhancement of rapid antimicrobial susceptibility testing through system automation.

Outcome: Invited to submit stage 2 application

 

NIHR201271: Self-management: A mixed-methods study of Young Peoples', parents’, and healthcare professionals’ views on the current DigiBete type 1 diabetes web-platform and App and proposed Artificial Intelligence-enabled Virtual Diabetes Clinic system.

Outcome: Invited to submit stage 2 application

 

Stage 1 applications not invited to submit to Stage 2

The following Stage 1 applications were discussed and rejected by the Sub-Committee or did not score highly enough to be considered for Stage 2 (applications sorted by highest average review score in descending order).

 

NIHR201212: A single-step medicine dispenser for improved adherence in older patients with dysphagia

Outcome: Rejected

 

NIHR201221: Identification of the added value of the MyCognition PRO app and feasibility of its introduction in the pathway of patients with suspected dementia.

Outcome: Rejected

 

NIHR201264: A multi-sensory virtual reality application for eating disorders that uses personalised avatars

Outcome: Rejected

 

NIHR201299: Market analysis and business model development for CodeRhythm, a sudden cardiac arrest prediction and alarm fatigue reduction algorithm

Outcome: Rejected

 

NIHR201191: Non-invasive autonomic neuromodulation (tVNS) device for the  treatment of cardiovascular disease

Outcome: Rejected

 

NIHR201195: Prototype Development to take the BalaTech AV Fistula Valve from TRL 3 to TRL 4 (Clinical Proof of Feasibility)

Outcome: Rejected

 

NIHR201218: AI-powered visual technology to diagnose rheumatoid arthritis disease-activity

Outcome: Rejected

 

NIHR201224: Treating Self-harm, Depression, Obsessive Compulsive Disorder, Generalised Anxiety and Bulimia Nervosa in young people through the use of Artificial Intelligence

Outcome: Rejected

 

NIHR201225: Determining Risks of Poor Birth Outcomes in Different Ethnicities in UK Cities

Outcome: Rejected

 

NIHR201244: M3Profiler - Isolating and profiling tumour derived microvesicles using an innovative multiplex, microfluidic assay

Outcome: Rejected

 

NIHR201245: New Medical Device

Outcome: Rejected

 

NIHR201247: Advanced precision diagnostic imaging modality for patient identification and stratification in dementia

Outcome: Rejected

 

NIHR201255: Using AI and predictive analytics as a foundation for preventative community mental health support

Outcome: Rejected

 

NIHR201267: FlexionFit-TKR Intelligent Home Based Rehabilitation Technology: Development and assessment of Efficacy, Usability, Health Economics, Patient Pathways & Clinical impact.

Outcome: Rejected

 

NIHR201197: Surgical Planning for Atresic Great Vessel Reconstruction in Children

Outcome: Rejected

 

NIHR201209: Usability and Human Factor Study on Patient Population within NHS with a Therapeutic Cognitive Application aiming at the delay of onset and slowing the progression of Dementia.

Outcome: Rejected

 

NIHR201219: Development of the NeutroCheck point-of-care medical device for use in chemotherapy patients at risk of neutropenic sepsis.

Outcome: Rejected

 

NIHR201235: Development of anomaly detection methodology for training deep neural networks to identify tumor tissue from biopsies removing the need for expert pixel-level annotations.

Outcome: Rejected

 

NIHR201237: GraduSOX - unique ink-polymer pads designed to focus compression over key perforating veins and lymphatics to heal and prevent recurrence of venous leg ulcers (VLUs)

Outcome: Rejected

 

NIHR201249: MIDS is a patented, Point of Care platform technology aimed firstly at High Sensitivity troponin testing for the early diagnosis of MI (‘Heart Attack’).

Outcome: Rejected

 

NIHR201277: Virtual Immersive Social Training for Children with Autism

Outcome: Rejected

 

NIHR201289: Building predictive models around volatile organic compounds found in breath to predict glucose levels and classify pre-diabetes and Type 2 diabetes.

Outcome: Rejected

 

NIHR201293: Real-time Wearable-free Patient Monitoring.

Outcome: Rejected

 

NIHR201193: Depression Rehabilitation and Assessment Mechanism (DReAM)

Outcome: Rejected

 

NIHR201196: An innovative healthcare device that directly addresses the severe consequences attributed to medication non-adherence

Outcome: Rejected

 

NIHR201202: Reducing stress with a wearable ear piece for vagus nerve stimulation and feedback

Outcome: Rejected

 

NIHR201236: Development of an acoustic separator for tumour-derived endothelial cell clusters.

Outcome: Rejected

 

NIHR201239: Tampliner® technology for a more comfortable, convenient, and secure hormone treatment during IVF.

Outcome: Rejected

 

NIHR201256: Smart Sock for the treatment of venous leg ulcers.

Outcome: Rejected

 

NIHR201266: Drug Delivery IoT Platform Enabled by Quantex Micro-Pumps

Outcome: Rejected

 

NIHR201269: Digital Support for Living with and Beyond Gynecological Cancer.

Outcome: Rejected

 

NIHR201272: AI-powered automated postural management and pressure care for older adults.

Outcome: Rejected

 

NIHR201275: Rapid Urine-based Bacteria Identification for UTI Diagnostics in the Community.

Outcome: Rejected

 

NIHR201287: Cost-efficient, rapid and effective personalised therapy selection for gastro-intestinal cancer patients.

Outcome: Rejected

 

NIHR201297: Seek All AI

Outcome: Rejected

 

NIHR201300: Neuronal Extent and Topography Mapping (NET): Non-invasive imaging biomarker for dementia diagnosis, stratification, staging and prognosis.

Outcome: Rejected

 

NIHR201302: The Smart Screw - Improving rehabilitation outcomes following knee surgery with an implantable sensor-enabled fixation screw.

Outcome: Rejected

 

NIHR201304: SMART Mattress for the Prevention of Pressure Injuries while inhibiting individual body deconditioning.

Outcome: Rejected

 

NIHR201308: Detection of Brain Tumours using Behavioural AI and Neurolinguistic Pattern Matching.

Outcome: Rejected

 

NIHR201189: Application of a novel  real time ECG wearable system with integrative AI platforms for primary care in the prevention of strokes.

 

NIHR201198: nOVel dEsigns foR oPerating tAbles to maximiSe Safety (OVERPASS)

Outcome: Rejected

 

NIHR201199: Stroke risk prediction using routine electronic health records enhanced by genetic data and machine learning

Outcome: Rejected

 

NIHR201201: Health economic evaluation and CE Mark research of KroniKare AI Wound Scanner for chronic wounds.

Outcome: Rejected

 

NIHR201207: Improving liver transplant outcomes and patient experience with a digital pre-surgical rehabilitation.

Outcome: Rejected

 

NIHR201227: SMART composite for tackling the epidemic of decay in childrens' teeth. Funding for upscaling production and addressing early product acceptance

Outcome: Rejected

 

NIHR201231: Diagnostic tool for real time and accurate classification of lung cancer tumours.

Outcome: Rejected

 

NIHR201241: Large-scale microfluidic bioprocessing platform for cell and gene therapy manufacturing

Outcome: Rejected

 

NIHR201251: Physical product design of a Lateral Flow Device (LFD) to monitor salivary Serum Ferritin (SF) to aid management of iron overload and iron deficiency conditions

Outcome: Rejected

 

NIHR201257: Click2Print Artificial eyes Phase I/II interventional device trial leading to regulatory approval for digital artificial eye market introduction

Outcome: Rejected

 

NIHR201262: E-textiles based wearable electrotherapy for osteoarthritis knee joint pain relief

Outcome: Rejected

 

NIHR201279: Digital Health Check for Cardiometabolic Risk Assessment

Outcome: Rejected

 

NIHR201286: AI-assisted portable breath analyser for respiratory disease diagnosis

Outcome: Rejected

 

NIHR201305: Wireless Intracranial Pressure Monitoring System

Outcome: Rejected

 

NIHR201187: Thorough market evaluation and proof of concept for "Knitted Skin" - a natural biodegradable wound care device

Outcome: Rejected

 

NIHR201206: SAFIRA: Safer Injection For Regional Anaesthesia: Creating a user-friendly device that makes the administration of regional anaesthesia precise and safer.

Outcome: Rejected

 

NIHR201208: A blood-based disease signature bioassay for the diagnosis, prognosis and treatment outcome measures of sporadic Alzheimer’s disease

Outcome: Rejected

 

NIHR201215: It's Time to Address the Scandal of Poor Medication Adherence: Technology can Help

Outcome: Rejected

 

NIHR201220: New model of monitoring exposure to medical ionising radiation

Outcome: Rejected

 

NIHR201238: Graducheck - Transformative technology as a sub-bandage pressure sensor to allow fool-proof, accurate, reproducible, optimised graduated compression profiles in the management of venous leg ulcers (VLUs).

Outcome: Rejected

 

NIHR201252: eScent; Wearable Biofeedback Loop Scent Intervention to Help Manage Anxiety Disorders

Outcome: Rejected

 

NIHR201278: Innovative, first-of-class, non-invasive device for the real-time diagnosis/exclusion of cardiac arrest: saving up to 8,000 lives annually in the UK, 1.7m globally with a global addressable market size of £20b.

Outcome: Rejected

 

NIHR201296: Non-invasive fully portable Type 2 Diabetes screening spectroscopic device

Outcome: Rejected

 

NIHR201303: SensTrain: a sensory discrimination device for the treatment of phantom Limb Pain

Outcome: Rejected

 

NIHR201306: The application of early diagnosis of dementia on treatment options and patient pathway choices. A comparison of different care models and analysis of the resulting health economics and patient outcomes.

Outcome: Rejected

 

NIHR201185: Breathomics for the diagnosis of Asthma

Outcome: Rejected

 

NIHR201194: Game-based Dementia Automated Test Apparatus (GDATA)

Outcome: Rejected

 

NIHR201205: Safe Count- A medical device to prevent accidentally retained surgical items(gauze swabs), one of the commonest "never events" ,considered the worst of patient harm and a key healthcare performance indicator

Outcome: Rejected

 

NIHR201210: Transforming NeuroRehabilitation Services through personalised and immersive Virtual Reality neurorehabilitation programmes

Outcome: Rejected

 

NIHR201226: Sepsis Pathogen Isolation, Capture and Electrosensing

Outcome: Rejected

 

NIHR201228: Clinical Knowledge Platform for Advancing Precision Medicine in Cardiometabolic Disease

Outcome: Rejected

 

NIHR201240: Bundle Health; an integrated digital health platform and ‘digital coach’, offering every patient continuity of care and expert early intervention for their long-term condition starting with IBS

Outcome: Rejected

 

NIHR201243: New Medical Service

Outcome: Rejected

 

NIHR201261: An online platform providing a proven, custom built, Cognitive Behavioural Therapy Programme of treatment for patients with respiratory long term conditions. Improving physical and mental health

Outcome: Rejected

 

NIHR201280: Development of a TRL6 patient centric, downloadable mobile telehealth solution for the preemptive and proactive management of chronic conditions including mental health using patient focused clinical decision support.

Outcome: Rejected

 

NIHR201294: Opportunities for A Rapid Point of Care Test for Faecal Occult Blood In Bowel Cancer Care

Outcome: Rejected

 

NIHR201298: LifeCourse Platform (LCP) for patient-owned health records and self-management

Outcome: Rejected

 

NIHR201192: Clinical evaluation of a wearable fetal movement monitoring garment

Outcome: Rejected

 

NIHR201200: PERI Tool - PErsonalised RIsk Tool

Outcome: Rejected

 

NIHR201211: Development of an automated bladder diary system to simplify measurement and improve assessment of female urinary incontinence

Outcome: Rejected

 

NIHR201229: Halo-Fuse. A novel drug delivery device for the penis

Outcome: Rejected

 

NIHR201276: New-material technology infection-detecting wound dressing which changes colour if a wound is becoming infected.

Outcome: Rejected

 

NIHR201291: Teen Health Planner - a digital tool to help teenage patients with long term health conditions to improve health outcomes during and after transition to adult health care.

Outcome: Rejected

 

NIHR201307: Bounce Time - A digital expert-led preventative mental health service for children and families

Outcome: Rejected

 

NIHR201180: Synthetic bone graft in putty form for dental, spine and orthopaedic application

Outcome: Rejected

 

NIHR201186: Breast ultrasound artificial intelligence image segmentation and quantification system.

Outcome: Rejected

 

NIHR201222: A portable respiratory improvement video game system using augmented reality and machine learning modelling with real-time human pose estimation within a cost-effective camera and computer console.

Outcome: Rejected

 

NIHR201233: Development of a personal urine capture device for elderly bed-bound users

Outcome: Rejected

 

NIHR201248: Empowering Type 1 diabetes patients to manage their condition effectively

Outcome: Rejected

 

NIHR201284: Prediction and Prevention of Falls: Testing the Machine Learning Algorithm interface and AI

Outcome: Rejected

 

NIHR201288: CE Marking of the COSMONiO Deep Learning Platform for Medical Applications

Outcome: Rejected

 

NIHR201301: Patient benefit from performance review after intervention informed by deeplearning segmentation in multimodal imaging study for prostate brachytherapy: a multicentre technical review

Outcome: Rejected

 

NIHR201216: The Water-Drop:  providing instant, independent access to fluids at all times for patients who would otherwise need to call for help just to get a drink.

Outcome: Rejected

 

NIHR201234: Validation of a new transport medium for inactivation of high consequence pathogens and preservation of nucleic acid in patient specimens

Outcome: Rejected

 

NIHR201258: Kit & Caboodle: A rehabilitation device for recovery and maintenance of fine upper limb motor control

Outcome: Rejected

 

NIHR201259: Non-invasive Screening Diagnostics for Control of Chronic Diseases – Anytime and Anywhere with Any Minimum Resources

Outcome: Rejected

 

NIHR201268: Developing a patient-facing digital platform that uses Machine Learning & Robotic Process Automation to automate and drive Quality Improvement initiatives based on qualitative feedback.

Outcome: Rejected

 

NIHR201232: Design and Manufacture of Electrotransfer Kit Prototype

Outcome: Rejected

 

NIHR201263: FLUSH: The impact of automation in monitoring fluid-balance & hydration of mobile inpatients within any healthcare environment

Outcome: Rejected

 

NIHR201274: New urinary catheter design development

Outcome: Rejected