Minutes of the Invention for Innovation (i4i) programme Sub-Committee meeting to discuss i4i Connect 3 Stage 1 (Expression of Interest) applications.
Date and location
Meeting held on 24 September 2019 at LGC Ltd, Grange House, 15 Church Street, Twickenham TW1 3NL.
In attendance
NIHR CCF i4i Secretariat
Mr Martin Hunt (Programme Director)
Professor Paul Sibbons (Chair)
Dr Ruth Nebauer (Assistant Director)
Dr Andrew Barber
Dr Emma Blamont
Mr Freddy Guenemi
Dr Chris Hill
Dr Caterina Lombardo
Mrs Paula Milton
Dr Ian Newington
Dr Raffaella Roncone
Sandra Nwokeoha
Edwin Tucker
Apologies
Dr Katherine Horner
Stage 1 applications invited to submit to Stage 2
The following Stage 1 applications were discussed and invited to submit to Stage 2 (applications sorted by highest average review score in descending order).
NIHR201250: FastWCE: Computer vision for the automated assessment of Crohn's Disease severity in Wireless Capsule Endoscopy
Outcome: Invited to submit stage 2 application
NIHR201253: SurePulse - heart rate monitoring for newborn babies
Outcome: Invited to submit stage 2 application
NIHR201270: Development of Clinical Prototype Novel Dry Powder Inhaler Device
Outcome: Invited to submit stage 2 application
NIHR201273: Decision support system for minimally invasive cerebral stenting surgeries
Outcome: Invited to submit stage 2 application
NIHR201283: Mental health therapy Provision, Research & Outcomes via Virtual Environments (IMPROVE)
Outcome: Invited to submit stage 2 application
NIHR201181: ViscoTurf - Preventing secondary diabetic foot ulceration
Outcome: Invited to submit stage 2 application
NIHR201204: Enhancing Children's mental resilience through Embers the Digital Dragon
Outcome: Invited to submit stage 2 application
NIHR201213: Wearable Brain Function Monitor
Outcome: Invited to submit stage 2 application
NIHR201230: Developing an innovative implanted resection cavity electrotherapy device for the treatment of Glioblastoma Multiforme (GBM).
Outcome: Invited to submit stage 2 application
NIHR201254: Prostate Liquid Biopsy Test for Risk Stratification of Prostate Cancer, preparation for CE marking.
Outcome: Invited to submit stage 2 application
NIHR201282: Further development of and evidence generation for a precision dosing tool for optimising chemotherapy dosing in advanced prostate cancer
Outcome: Invited to submit stage 2 application
NIHR201292: NeuroPlatform: A novel digital therapy platform aiding the transition from NHS to home for stroke survivors by making rehabilitation enjoyable and affordable.
Outcome: Invited to submit stage 2 application
NIHR201184: Neuroimaging headband design and build: low-cost, non-invasive, portable medical device for determination of personalised dementia risk
Outcome: Invited to submit stage 2 application
NIHR201217: Enable patients to become players with Playphysio
Outcome: Invited to submit stage 2 application
NIHR201246: Personalised digital therapy and self-care support for the management of Irritable Bowel Syndrome: Zemedy-AI
Outcome: Invited to submit stage 2 application
NIHR201260: Physio Exerciser Smartphone App for enhanced patient rehabilitation following musculoskeletal injury
Outcome: Invited to submit stage 2 application
NIHR201265: Establishing the efficacy of smart glasses for patients with central vision loss
Outcome: Invited to submit stage 2 application
NIHR201281: Transforming management of advanced prostate cancer: Increasing clinical productivity and capacity and empowering men through digital health
Outcome: Invited to submit stage 2 application
NIHR201183: Ambra1 STRatification of HPV positive Oropharyngeal Squamous cell carcinoma for DE- escalation Treatment regimens (ASTRO-DET)
Outcome: Invited to submit stage 2 application
NIHR201190: Bridgit home support and integrated social care provision.
Outcome: Invited to submit stage 2 application
NIHR201203:The Development of Exergaming for Spinal Cord Rehabilitation
Outcome: Invited to submit stage 2 application
NIHR201214: BioPhotonics for Medical Devices
Outcome: Invited to submit stage 2 application
NIHR201242: Clinical verification study for further development of a real-time, remote and wearable hydration monitoring system.
Outcome: Invited to submit stage 2 application
NIHR201285: IoT Automated Quantification of Muscular Rigidity and Underlying Neural Signals in Parkinson’s Disease (PD)
Outcome: Invited to submit stage 2 application
NIHR201290: Improving Myocardial Perfusion Imaging Processing for the Management of Patients with Cardiovascular Disease using Machine Learning.
Outcome: Invited to submit stage 2 application
NIHR201295: Enhancement of rapid antimicrobial susceptibility testing through system automation.
Outcome: Invited to submit stage 2 application
NIHR201271: Self-management: A mixed-methods study of Young Peoples', parents’, and healthcare professionals’ views on the current DigiBete type 1 diabetes web-platform and App and proposed Artificial Intelligence-enabled Virtual Diabetes Clinic system.
Outcome: Invited to submit stage 2 application
Stage 1 applications not invited to submit to Stage 2
The following Stage 1 applications were discussed and rejected by the Sub-Committee or did not score highly enough to be considered for Stage 2 (applications sorted by highest average review score in descending order).
NIHR201212: A single-step medicine dispenser for improved adherence in older patients with dysphagia
Outcome: Rejected
NIHR201221: Identification of the added value of the MyCognition PRO app and feasibility of its introduction in the pathway of patients with suspected dementia.
Outcome: Rejected
NIHR201264: A multi-sensory virtual reality application for eating disorders that uses personalised avatars
Outcome: Rejected
NIHR201299: Market analysis and business model development for CodeRhythm, a sudden cardiac arrest prediction and alarm fatigue reduction algorithm
Outcome: Rejected
NIHR201191: Non-invasive autonomic neuromodulation (tVNS) device for the treatment of cardiovascular disease
Outcome: Rejected
NIHR201195: Prototype Development to take the BalaTech AV Fistula Valve from TRL 3 to TRL 4 (Clinical Proof of Feasibility)
Outcome: Rejected
NIHR201218: AI-powered visual technology to diagnose rheumatoid arthritis disease-activity
Outcome: Rejected
NIHR201224: Treating Self-harm, Depression, Obsessive Compulsive Disorder, Generalised Anxiety and Bulimia Nervosa in young people through the use of Artificial Intelligence
Outcome: Rejected
NIHR201225: Determining Risks of Poor Birth Outcomes in Different Ethnicities in UK Cities
Outcome: Rejected
NIHR201244: M3Profiler - Isolating and profiling tumour derived microvesicles using an innovative multiplex, microfluidic assay
Outcome: Rejected
NIHR201245: New Medical Device
Outcome: Rejected
NIHR201247: Advanced precision diagnostic imaging modality for patient identification and stratification in dementia
Outcome: Rejected
NIHR201255: Using AI and predictive analytics as a foundation for preventative community mental health support
Outcome: Rejected
NIHR201267: FlexionFit-TKR Intelligent Home Based Rehabilitation Technology: Development and assessment of Efficacy, Usability, Health Economics, Patient Pathways & Clinical impact.
Outcome: Rejected
NIHR201197: Surgical Planning for Atresic Great Vessel Reconstruction in Children
Outcome: Rejected
NIHR201209: Usability and Human Factor Study on Patient Population within NHS with a Therapeutic Cognitive Application aiming at the delay of onset and slowing the progression of Dementia.
Outcome: Rejected
NIHR201219: Development of the NeutroCheck point-of-care medical device for use in chemotherapy patients at risk of neutropenic sepsis.
Outcome: Rejected
NIHR201235: Development of anomaly detection methodology for training deep neural networks to identify tumor tissue from biopsies removing the need for expert pixel-level annotations.
Outcome: Rejected
NIHR201237: GraduSOX - unique ink-polymer pads designed to focus compression over key perforating veins and lymphatics to heal and prevent recurrence of venous leg ulcers (VLUs)
Outcome: Rejected
NIHR201249: MIDS is a patented, Point of Care platform technology aimed firstly at High Sensitivity troponin testing for the early diagnosis of MI (‘Heart Attack’).
Outcome: Rejected
NIHR201277: Virtual Immersive Social Training for Children with Autism
Outcome: Rejected
NIHR201289: Building predictive models around volatile organic compounds found in breath to predict glucose levels and classify pre-diabetes and Type 2 diabetes.
Outcome: Rejected
NIHR201293: Real-time Wearable-free Patient Monitoring.
Outcome: Rejected
NIHR201193: Depression Rehabilitation and Assessment Mechanism (DReAM)
Outcome: Rejected
NIHR201196: An innovative healthcare device that directly addresses the severe consequences attributed to medication non-adherence
Outcome: Rejected
NIHR201202: Reducing stress with a wearable ear piece for vagus nerve stimulation and feedback
Outcome: Rejected
NIHR201236: Development of an acoustic separator for tumour-derived endothelial cell clusters.
Outcome: Rejected
NIHR201239: Tampliner® technology for a more comfortable, convenient, and secure hormone treatment during IVF.
Outcome: Rejected
NIHR201256: Smart Sock for the treatment of venous leg ulcers.
Outcome: Rejected
NIHR201266: Drug Delivery IoT Platform Enabled by Quantex Micro-Pumps
Outcome: Rejected
NIHR201269: Digital Support for Living with and Beyond Gynecological Cancer.
Outcome: Rejected
NIHR201272: AI-powered automated postural management and pressure care for older adults.
Outcome: Rejected
NIHR201275: Rapid Urine-based Bacteria Identification for UTI Diagnostics in the Community.
Outcome: Rejected
NIHR201287: Cost-efficient, rapid and effective personalised therapy selection for gastro-intestinal cancer patients.
Outcome: Rejected
NIHR201297: Seek All AI
Outcome: Rejected
NIHR201300: Neuronal Extent and Topography Mapping (NET): Non-invasive imaging biomarker for dementia diagnosis, stratification, staging and prognosis.
Outcome: Rejected
NIHR201302: The Smart Screw - Improving rehabilitation outcomes following knee surgery with an implantable sensor-enabled fixation screw.
Outcome: Rejected
NIHR201304: SMART Mattress for the Prevention of Pressure Injuries while inhibiting individual body deconditioning.
Outcome: Rejected
NIHR201308: Detection of Brain Tumours using Behavioural AI and Neurolinguistic Pattern Matching.
Outcome: Rejected
NIHR201189: Application of a novel real time ECG wearable system with integrative AI platforms for primary care in the prevention of strokes.
NIHR201198: nOVel dEsigns foR oPerating tAbles to maximiSe Safety (OVERPASS)
Outcome: Rejected
NIHR201199: Stroke risk prediction using routine electronic health records enhanced by genetic data and machine learning
Outcome: Rejected
NIHR201201: Health economic evaluation and CE Mark research of KroniKare AI Wound Scanner for chronic wounds.
Outcome: Rejected
NIHR201207: Improving liver transplant outcomes and patient experience with a digital pre-surgical rehabilitation.
Outcome: Rejected
NIHR201227: SMART composite for tackling the epidemic of decay in childrens' teeth. Funding for upscaling production and addressing early product acceptance
Outcome: Rejected
NIHR201231: Diagnostic tool for real time and accurate classification of lung cancer tumours.
Outcome: Rejected
NIHR201241: Large-scale microfluidic bioprocessing platform for cell and gene therapy manufacturing
Outcome: Rejected
NIHR201251: Physical product design of a Lateral Flow Device (LFD) to monitor salivary Serum Ferritin (SF) to aid management of iron overload and iron deficiency conditions
Outcome: Rejected
NIHR201257: Click2Print Artificial eyes Phase I/II interventional device trial leading to regulatory approval for digital artificial eye market introduction
Outcome: Rejected
NIHR201262: E-textiles based wearable electrotherapy for osteoarthritis knee joint pain relief
Outcome: Rejected
NIHR201279: Digital Health Check for Cardiometabolic Risk Assessment
Outcome: Rejected
NIHR201286: AI-assisted portable breath analyser for respiratory disease diagnosis
Outcome: Rejected
NIHR201305: Wireless Intracranial Pressure Monitoring System
Outcome: Rejected
NIHR201187: Thorough market evaluation and proof of concept for "Knitted Skin" - a natural biodegradable wound care device
Outcome: Rejected
NIHR201206: SAFIRA: Safer Injection For Regional Anaesthesia: Creating a user-friendly device that makes the administration of regional anaesthesia precise and safer.
Outcome: Rejected
NIHR201208: A blood-based disease signature bioassay for the diagnosis, prognosis and treatment outcome measures of sporadic Alzheimer’s disease
Outcome: Rejected
NIHR201215: It's Time to Address the Scandal of Poor Medication Adherence: Technology can Help
Outcome: Rejected
NIHR201220: New model of monitoring exposure to medical ionising radiation
Outcome: Rejected
NIHR201238: Graducheck - Transformative technology as a sub-bandage pressure sensor to allow fool-proof, accurate, reproducible, optimised graduated compression profiles in the management of venous leg ulcers (VLUs).
Outcome: Rejected
NIHR201252: eScent; Wearable Biofeedback Loop Scent Intervention to Help Manage Anxiety Disorders
Outcome: Rejected
NIHR201278: Innovative, first-of-class, non-invasive device for the real-time diagnosis/exclusion of cardiac arrest: saving up to 8,000 lives annually in the UK, 1.7m globally with a global addressable market size of £20b.
Outcome: Rejected
NIHR201296: Non-invasive fully portable Type 2 Diabetes screening spectroscopic device
Outcome: Rejected
NIHR201303: SensTrain: a sensory discrimination device for the treatment of phantom Limb Pain
Outcome: Rejected
NIHR201306: The application of early diagnosis of dementia on treatment options and patient pathway choices. A comparison of different care models and analysis of the resulting health economics and patient outcomes.
Outcome: Rejected
NIHR201185: Breathomics for the diagnosis of Asthma
Outcome: Rejected
NIHR201194: Game-based Dementia Automated Test Apparatus (GDATA)
Outcome: Rejected
NIHR201205: Safe Count- A medical device to prevent accidentally retained surgical items(gauze swabs), one of the commonest "never events" ,considered the worst of patient harm and a key healthcare performance indicator
Outcome: Rejected
NIHR201210: Transforming NeuroRehabilitation Services through personalised and immersive Virtual Reality neurorehabilitation programmes
Outcome: Rejected
NIHR201226: Sepsis Pathogen Isolation, Capture and Electrosensing
Outcome: Rejected
NIHR201228: Clinical Knowledge Platform for Advancing Precision Medicine in Cardiometabolic Disease
Outcome: Rejected
NIHR201240: Bundle Health; an integrated digital health platform and ‘digital coach’, offering every patient continuity of care and expert early intervention for their long-term condition starting with IBS
Outcome: Rejected
NIHR201243: New Medical Service
Outcome: Rejected
NIHR201261: An online platform providing a proven, custom built, Cognitive Behavioural Therapy Programme of treatment for patients with respiratory long term conditions. Improving physical and mental health
Outcome: Rejected
NIHR201280: Development of a TRL6 patient centric, downloadable mobile telehealth solution for the preemptive and proactive management of chronic conditions including mental health using patient focused clinical decision support.
Outcome: Rejected
NIHR201294: Opportunities for A Rapid Point of Care Test for Faecal Occult Blood In Bowel Cancer Care
Outcome: Rejected
NIHR201298: LifeCourse Platform (LCP) for patient-owned health records and self-management
Outcome: Rejected
NIHR201192: Clinical evaluation of a wearable fetal movement monitoring garment
Outcome: Rejected
NIHR201200: PERI Tool - PErsonalised RIsk Tool
Outcome: Rejected
NIHR201211: Development of an automated bladder diary system to simplify measurement and improve assessment of female urinary incontinence
Outcome: Rejected
NIHR201229: Halo-Fuse. A novel drug delivery device for the penis
Outcome: Rejected
NIHR201276: New-material technology infection-detecting wound dressing which changes colour if a wound is becoming infected.
Outcome: Rejected
NIHR201291: Teen Health Planner - a digital tool to help teenage patients with long term health conditions to improve health outcomes during and after transition to adult health care.
Outcome: Rejected
NIHR201307: Bounce Time - A digital expert-led preventative mental health service for children and families
Outcome: Rejected
NIHR201180: Synthetic bone graft in putty form for dental, spine and orthopaedic application
Outcome: Rejected
NIHR201186: Breast ultrasound artificial intelligence image segmentation and quantification system.
Outcome: Rejected
NIHR201222: A portable respiratory improvement video game system using augmented reality and machine learning modelling with real-time human pose estimation within a cost-effective camera and computer console.
Outcome: Rejected
NIHR201233: Development of a personal urine capture device for elderly bed-bound users
Outcome: Rejected
NIHR201248: Empowering Type 1 diabetes patients to manage their condition effectively
Outcome: Rejected
NIHR201284: Prediction and Prevention of Falls: Testing the Machine Learning Algorithm interface and AI
Outcome: Rejected
NIHR201288: CE Marking of the COSMONiO Deep Learning Platform for Medical Applications
Outcome: Rejected
NIHR201301: Patient benefit from performance review after intervention informed by deeplearning segmentation in multimodal imaging study for prostate brachytherapy: a multicentre technical review
Outcome: Rejected
NIHR201216: The Water-Drop: providing instant, independent access to fluids at all times for patients who would otherwise need to call for help just to get a drink.
Outcome: Rejected
NIHR201234: Validation of a new transport medium for inactivation of high consequence pathogens and preservation of nucleic acid in patient specimens
Outcome: Rejected
NIHR201258: Kit & Caboodle: A rehabilitation device for recovery and maintenance of fine upper limb motor control
Outcome: Rejected
NIHR201259: Non-invasive Screening Diagnostics for Control of Chronic Diseases – Anytime and Anywhere with Any Minimum Resources
Outcome: Rejected
NIHR201268: Developing a patient-facing digital platform that uses Machine Learning & Robotic Process Automation to automate and drive Quality Improvement initiatives based on qualitative feedback.
Outcome: Rejected
NIHR201232: Design and Manufacture of Electrotransfer Kit Prototype
Outcome: Rejected
NIHR201263: FLUSH: The impact of automation in monitoring fluid-balance & hydration of mobile inpatients within any healthcare environment
Outcome: Rejected
NIHR201274: New urinary catheter design development
Outcome: Rejected