Minutes of the Invention for Innovation (i4i) Programme Sub-Committee Meeting to discuss applications to Product Development Awards (PDA) Call 25 Stage 1
Date and Location
Meeting held on Monday 06 February 2023 via Zoom Virtual Meeting
In attendance
Sub-Committee
Ms Emma Palmer Foster (Chair)
Professor Paul Sibbons (Deputy Chair)
Mr Charles Spicer (Chair)
Professor David Hawkes (Deputy Chair)
i4i Secretariat
Professor Mike Lewis (Programme Director)
Dr Ruth Nebauer (Assistant Director)
Dr Andrew Barber
Mr Alex Zabala Findlay
Ms Eva Garritsen
Ms Ami Hodges
Dr Caterina Lombardo
Mrs Paula Milton
Mr Fergus Morris
Dr Ian Newington
Dr Antonio Ruiz
Mr Luis Tojo
Dr Maryam Tamaddon
Dr Laura Tornatore
Dr Francesca Troiani
Mr Edwin Tucker
Ms Kasia Zmarzly
Stage 1 applications invited to submit to Stage 2:
NIHR205521: CyteCount: a novel bacterial electrophysiology method for rapid phenotypic antibiotic susceptibility testing of bacteria detected in clinical blood cultures.
Outcome: Invite to Stage 2
NIHR205512: Aide Health - Comorbidity Platform A digital service, using natural language to improve comorbidity management, improving quality of life by reducing treatment burden, adverse events, and unplanned care.
Outcome: Invite to Stage 2
NIHR205511: Meropenem therapeutic drug monitoring to reduce antimicrobial resistance: Analytical validity of a novel meropenem assay
Outcome: Invite to Stage 2
NIHR205509: BabEEG: Implementing a dry, easy-setup EEG in neonatal units
Outcome: Invite to Stage 2
NIHR205508: Proton radiography for adaptive radiotherapy and image guidance using a novel
image detection system
Outcome: Invite to Stage 2
NIHR205502: Optimisation and clinical validation of a digital diagnostic system for small bowel biopsies
Outcome: Invite to Stage 2
NIHR205499: Development and use of Orpheus Mind Technology’s Destroyer Tracks to support management of depression and anxiety in Step 2 Improving Access to Psychological Therapies (IAPT) service referrals: the Orpheus-IAPT study
Outcome: Invite to Stage 2
NIHR205493: Measuring the immune response to tumour development for effective and cost effective early-stage tumour detection using amino acid biomarkers
Outcome: Invite to Stage 2
NIHR205492: Clinical Validation of a Low Cost and Scalable Blood Test for Screening Diabetic and Obese Patients for Non-Alcoholic Steatohepatitis.
Outcome: Invite to Stage 2
NIHR205486: SERG-one - an AI-powered, Mechanomyography (MMG) Sensor Platform to optimise therapy for Parkinson's Disease
Outcome: Invite to Stage 2
NIHR205474: The Children's Adaptive Deep brain stimulation for Epilepsy Trial (CADET): Adapt
Outcome: Invite to Stage 2
NIHR205473: Optimisation of a patented e-textile stimulation device to support recovery of muscle activity following stroke, by evaluating the recovery of movement in the arm and user-experience of the device.
Outcome: Invite to Stage 2
NIHR205472: Developing an AI tool to identify those patients with abnormal bile ducts at higher risk of injury during gallbladder surgery
Outcome: Invite to Stage 2
NIHR205471: In Human Feasibility Trials and Usability Development for 1View – Augmented reality software and platform for inter-operative guidance during Mechanical Thrombectomy (MT) procedures - Giving Stroke victims a better chance
Outcome: Invite to Stage 2
NIHR205467: Clinical translation and commercialisation of ORBIT (Online Remote Behavioural Intervention for Tics): creating a patient-ready product and business case for NHS adoption in the UK
Outcome: Invite to Stage 2
NIHR205460: The neoSCB app: a mobile app for screening neonatal jaundice
Outcome: Invite to Stage 2
Stage 1 applications not invited to submit to Stage 2:
NIHR205522: Artificial Intelligence for Direct Patient Care of people with long-term respiratory Illness.
Outcome: Reject
NIHR205520: Clinical translation and development of N-CORN: an innovative dry and stable human cornea transplant-solution, transforming corneal disease treatment
Outcome: Reject
NIHR205519: Remote Monitoring of Infant Vital Signs using PuffinPLUS™ Multi-Sensor Device
Outcome: Reject
NIHR205518: Nano-structured hierarchical aptamer sensors for non-invasive, point of care, repeated cortisol measurements
Outcome: Reject
NIHR205517: Development of a next-generation gynaecological drug delivery device for enhanced patient comfort and convenience
Outcome: Reject
NIHR205516: AIHFA - AI Heart Failure Algorithm Project for the Early Detection of HF in clinical settings
Outcome: Reject
NIHR205514: Diagnostic Respiratory Electronic Apnoea Module (D.R.E.A.M)
Outcome: Reject
NIHR205513: Post-Operative Ileus Sound-based Evaluation - PDA
Outcome: Reject
NIHR205510: Digitalised manufacturing of prosthetic sockets for lower limb amputees using sustainably sourced material
Outcome: Reject
NIHR205507: Development and evaluation of Clinical Task Recommendation system (real-time, highly accessible clinical decision support) integrated directly from and into a clinical task management platform, Lister.
Outcome: Reject
NIHR205506: Regulatory clearance, scale-for-manufacture, and product development of an innovate respiratory measurement device for self-management and remote monitoring
Outcome: Reject
NIHR205505: Clinical validation of Artificial Intelligence (AI) Guided Clinical Coaching – A pioneering collaboration between Health Innovation Manchester, University of Manchester and HN Ltd to predict and prevent unplanned care.
Outcome: Reject
NIHR205504: Generating personalised dietary advice from a smartphone food diary to alleviate Irritable Bowel Syndrome (IBS) symptoms.
Outcome: Reject
NIHR205503: Developing and testing the use of AI in delivering personalised plans of care for people living with type 2 diabetes and at least one other long term condition
Outcome: Reject
NIHR205501: Using AI & 3D depth technology to monitor and predict diabetic foot ulcer progression remotely
Outcome: Reject
NIHR205500: ReMo: Remote Motion Capture to Empower Musculoskeletal Care
Outcome: Reject
NIHR205498: Twin Soft Robotic Arms for Endoluminal Surgery (TwiSrs)
Outcome: Reject
NIHR205497: LIT™-AI: Artificial intelligence-enhanced point-of-care test for early detection of metastatic prostate cancer
Outcome: Reject
NIHR205496: Development of a rapid diagnostic point-of-care test of wound infections.
Outcome: Reject
NIHR205495: Crainio non-invasive intracranial pressure monitor for traumatic brain injury: product development
Outcome: Reject
NIHR205494: Bipolar Focused Objective Calculations of Affect (BiFOCAl)
Outcome: Reject
NIHR205491: Improving Detection, Reporting and Management of Osteoporosis (IDRAMO)
Outcome: Reject
NIHR205490: Improving maternal outcomes through accurately predicting disposition to hypertensive disorders in pregnancy, using the Salurate self-test device (SALURATE).
Outcome: Reject
NIHR205489: M.A.R.I.O - Mobile Assisted Reconstruction In Orthopaedics: product development, regulatory establishment and clinical evaluation
Outcome: Reject
NIHR205488: Foresight: Artificial Intelligence Platform for Dynamic, Real-Time Prediction and Prevention of Multi-Organ Failure in Intensive Care Units
Outcome: Reject
NIHR205487: BBV_TestPrompt2 – developing and testing a clinical decision support application to prompt blood-borne virus (BBV) testing in primary care
Outcome: Reject
NIHR205485: A blood test to transform prostate cancer diagnosis
Outcome: Reject
NIHR205484: Transforming outcomes for patients with Epidermolysis Bullosa: Research into Moisture Mitts and Sock Technology (RE- MMiST).
Outcome: Reject
NIHR205483: Optimisation of Artificial intelligence Spirometry Interpretation Software in primary care (OASIS)
Outcome: Reject
NIHR205482: Initiative Thermotherapy in Head and Neck Cancers (iTHANC)
Outcome: Reject
NIHR205481: A minimally invasive technology for the treatment of uterine fibroids: Bi-modal Electric Tissue Ablation (BETA).
Outcome: Reject
NIHR205480: OrthoSense: Using wearable technology to quantify knee instability
Outcome: Reject
NIHR205479: A Low-Cost Wearable Solution for Remote Body Temperature Monitoring and Diagnosis
Outcome: Reject
NIHR205478: Final design up to First in Human Studies for a modular ventilation and anaesthesia system to improve efficiency and reduce patient harm on life support.
Outcome: Reject
NIHR205477: Early wound infection diagnosis using novel bacterial detection technology
Outcome: Reject
NIHR205476: A risk prediction score for Alzheimer’s disease using ciliopathic single nucleotide polymorphisms
Outcome: Reject
NIHR205475: Development of technology for personalised monitoring of blood potassium levels
Outcome: Reject
NIHR205470: Laparoscopic common bile duct exploration and suturing simulator based on augmented reality and haptic feedback for surgical training.
Outcome: Reject
NIHR205469: BioRadiomics: Monoclonal Enabled biological Imaging Platform
Outcome: Reject
NIHR205468: Development and evidence generation for a multimodal combination biomarker-based health monitoring and early warning system for patients receiving long-term specialist care
Outcome: Reject
NIHR205466: The co-design and development of an Extended Reality balance training system for people with Chronic Obstructive Pulmonary Disease
Outcome: Reject
NIHR205465: Compact TriteQ (CTTQ) Medical - Development of novel, glasses-free stereoscopic display for training, tele-ophthalmology and surgery.
Outcome: Reject
NIHR205464: Regulatory-compliance manufacture of osteochondral scaffold for repair of large osteochondral defects
Outcome: Reject
NIHR205463: IRIS: Next generation point-of-care testing for respiratory viral infection screening in an Emergency Department (ED) settings.
Outcome: Reject
NIHR205462: 3D concept printing as a mechanism to embed smart technology for biofeedback and gait modifications in foot orthoses to control footfall.
Outcome: Reject
NIHR205459: Screening Microorganisms in Ascitic Fluid; Ascitic Bacteria Counting and Detection. A2D
Outcome: Reject
NIHR205458: SmartPatch system for amblyopia management in children age 5-8 years: prototype development and phase 2b feasibility trial
Outcome: Reject
NIHR205457: Conformable Microfluidic Force Sensors for Precision Joint Replacement Surgery
Outcome: Reject
NIHR205456: Development of a point-of-care device for rapid urinary tract infection diagnosis in people living with dementia
Outcome: Reject
NIHR205455: Computer Aided Diagnostic and Design System (CADDS) for spine applications: Artificial intelligence powered software platform for automatic diagnostics and design of patient specific implants delivering improved osseointegration.
Outcome: Reject
NIHR205454: Development of a sensor probe for direct real-time brain-chemistry monitoring in brain injury patients ?
Outcome: Reject
NIHR205453: The VISION Project: Development and validation of a Breast cancer therapeutic response predictive algorithm for early Triple Negative Breast Cancers (TNBC).
Outcome: Reject
NIHR205452: ARCHi2: Automated Recognition and Classification of Hip fractures
Outcome: Reject
NIHR205451: A Novel Antimicrobial Medical Device Coating for Orthopaedic Applications
Outcome: Reject
NIHR205450: Research and development of a fully deployable Headway Digital Medical Device facilitating family-based self-driven healthcare for mentally unwell children and young people, integrated with clinical support.
Outcome: Reject
NIHR205449: Development and early validation of the Exovent Negative Pressure Ventilator
Outcome: Reject
NIHR205622: Evaluation of the Safety and Efficacy of the ShiVent, a Non-electric, Non-invasive Ventilator in patients with Respiratory Failure - a Phase 2 Trial
Outcome: Reject
The following Stage 1 application withdrew from the competition:
NIHR205523: Development and pre-market evaluation of AI-assisted dental disease detection with radiography