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Research for Patient Benefit - Competition 44 Stage 2 and Competition 45 Stage 1 minutes, East of England

Contents

Published: 06 December 2021

Version: 1.0 - September 2021

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Minutes for the Research for Patient Benefit (RfPB) programme East of England Regional Advisory Committee meeting to discuss Stage 2 applications to competition 44 and Stage 1 applications to competition 45.

Date and Location

Friday 17 September 2021 Virtual Meeting

In attendance

Committee members

Professor Tracey Sach (Chair)
Mrs Abigail Dennington-Price
Dr Robbie Duschinsky
Professor Diana Gorog
Dr Rebecca Harmston
Dr Julia Jones
Dr Anne Killett
Dr Jacqueline Mitton
Professor Carl Philpott
Dr Wendi Qian
Dr Ewen Speed
Dr Murray Smith
Dr Toby Smith
Dr Juliet Usher-Smith

Secretariat

Mr Simon Goodwin (NIHR CCF)
Dr Jennie Hejdenberg (NIHR CCF)
Ms Lara Oh (NIHR CCF)
Ms Gemma Paine (NIHR CCF)
Ms Cherrelle Salmon (NIHR CCF)

Observers

Mrs Abigail Dennington-Price - Public member
Dr Mark Goodall - (RDS NW)
Dr Cath McParlin - (RDS NE)
Dr Kritika Samsi - King’s College London

Apologies

Apologies were received from Dr Robbie Duschinsky, Dr Julia Jones, Dr Murray Smith.

Competition 44 stage 2 applications considered

1.1 NIHR203045: Improving Parental Engagement in Child Death Review

Conflicts: None

Final outcome: Conditional support

1.2 NIHR203023: A systematic review of parents’/carers' needs, and interventions to support parents/carers of young people with mental health problems receiving mental health services: evidence synthesis with stakeholder engagement to provide practical recommendations

Conflicts: None

Final outcome: Conditional support

1.3 NIHR203160: Predicting the 2- and 5-year risk of kidney failure for patients with chronic kidney disease in the United Kingdom: external validation and update of the Kidney Failure Risk Equation

Conflicts: Dr Juliet Usher-Smith left the room

Final outcome: Conditional support

1.4 NIHR203035: Comparing pharmacological and non-pharmacological interventions for adults with Attention-Deficit/Hyperactivity Disorder (ADHD): systematic review and network meta-analysis

Conflicts: Dr Toby Smith and Professor Tracey Sach left the room.

Final outcome: Conditional support

1.5 NIHR203141: ACCorD: Adhesive Capsulitis Corticosteroid or Dilation

Conflicts: Dr Toby Smith remained out of the room.

Final outcome: Conditional support

1.6 NIHR203026: Vertebral fracture clinical decision tool for older women with back pain (Vfrac) – a feasibility study

Conflicts: Dr Toby Smith remained out of the room.

Final outcome: Conditional support

1.7 NIHR203024: Process evaluation of embedding the CoolCuddle intervention into neonatal intensive care units.

Conflicts: None

Final outcome: Conditional support

Competition 45 stage 1 applications considered

2.1 NIHR203633: Understanding and identifying ways to optimise cancer recognition, referral, and management for people with dementia in primary and community care: a qualitative interview study

Conflicts: Dr Juliet Usher-Smith left the room.

Outcome: Invite to Stage 2

2.2 NIHR203625: Feasibility randomised control study of vascular closed Incision negative pressure dressings following major lower limb amputation (VIPER).

Conflicts: None

Outcome: Invite to Stage 2

2.3 NIHR203582: A randomised controlled trial to assess the feasibility of adopting a primary care lay health worker delivered intervention to increase cancer screening uptake among women in areas of high socio-economic disadvantage

Conflicts: Dr Juliet Usher-Smith left the room.

Outcome: Rejected

2.4 NIHR203645: Uncontrolled Donation after Circulatory Death - a Tier 3 Development Study

Conflicts: Dr Wendi Qian left the room.

Outcome: Rejected

2.5 NIHR203578: Thresholds used for detecting postural hypotension

Conflicts: None

Outcome: Rejected

2.6 NIHR203617: Understanding prosthetics prescription from patients' and clinicians' perspectives: The UPP study

Conflicts: None

Outcome: Rejected

2.7 NIHR203519: Co-production of a care pathway for dislocation after total hip replacement: the HipCare Collaborative

Conflicts: Dr Toby Smith left the room

Outcome: Rejected

2.8 NIHR203554: The Lycra Sleeve® as an adjunct to upper-limb rehabilitation after stroke: Feasibility with embedded proof-of-concept multi-centred randomised controlled trial

Conflicts: None

Outcome: Rejected

2.9 NIHR203530: Supporting the ambulance service to safely convey fewer patients to hospital by developing a risk prediction tool: Risk of ADverse Outcomes after a Suspected Seizure (RADOSS)

Conflicts: None

Outcome: Invite to Stage 2

Outcomes tables

The tables below display the mean score for each application that was assessed in the regional assessment committee meeting, and excludes applications which were rejected during the scrutiny and triage processes. The number of applications receiving each mean score are listed. The RfPB fundable range is 6-10, although a score of 6-10 does not guarantee funding or an invitation to Stage 2. In exceptional circumstances and with approval from the Programme Director, applications may be invited/funded which fall below the fundable range.

In exceptional circumstances, applications which fall below the fundable range may be invited to Stage 2 or recommended for funding by the Committee. The Programme Director reviews in detail any applications recommended for funding with a score below 7.

Competition 45 stage 1

ScoreRangeNumber of applications
9.0 - 10.0 Invited 0
8.0 - 8.9 Invited 0
7.0 - 7.9 Invited 3
6.0 - 6.9 Rejected 2
5.0 - 5.9 Rejected 4
4.0 - 4.9 Rejected 0
3.0 - 3.9 Rejected 0
2.0 - 2.9 Rejected 0
1.0 - 1.9 Rejected 0

Competition 44 stage 2

ScoreRangeNumber of applications
9.0 - 10.0 Fundable 1
8.0 - 8.9 Fundable 1
7.0 - 7.9 Fundable 4
6.0 - 6.9 Fundable 1
5.0 - 5.9 Rejected 0
4.0 - 4.9 Rejected 0
3.0 - 3.9 Rejected 0
2.0 - 2.9 Rejected 0
1.0 - 1.9 Rejected 0