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Research for Patient Benefit - Competition 45 Stage 2 and Competition 46 Stage 1 minutes, East of England


12 April 2022


1 - April 2022


Minutes for the Research for Patient Benefit (RfPB) programme East of England Regional Advisory Committee meeting to discuss Stage 2 applications to competition 45 and Stage 1 applications to competition 46.

Date and Location

Friday 21 January 2022 Virtual Meeting

In attendance

Committee members

Professor Tracey Sach (Chair)
Mrs Abigail Dennington-Price
Dr Robbie Duschinsky
Dr Julia Jones
Professor Carl Philpott
Dr Wendi Qian
Dr Murray Smith
Dr Toby Smith
Dr Juliet Usher-Smith


Mr Simon Goodwin (NIHR CCF)
Dr Elisabeth Kugelberg (NIHR CCF)
Dr Ianina Conte (NIHR CCF)
Ms Katie Prangle (NIHR CCF)
Ms Sophie Tattersall (NIHR CCF)
Professor Sue Ziebland (Programme Director)


Monica Leverton (Schools)
Professor Andrew Bateman (RDS - EE)


Apologies were received from Dr Jacqueline Mitton.

Competition 45 stage 2 applications considered

1.1 NIHR203625: Feasibility randomised control study of vascular closed Incision negative pressure dressings following major lower limb amputation (VIPER)

Conflicts: None

Final outcome: Reject

1.2 NIHR203530: Supporting the ambulance service to safely convey fewer patients to hospital by developing a risk prediction tool: Risk of ADverse Outcomes after a Suspected Seizure (RADOSS)

Conflicts: None

Final outcome: Conditional support

1.3 NIHR203633: Understanding and identifying ways to optimise cancer recognition, referral, and management for people with dementia in primary and community care: a qualitative interview study

Conflicts: Dr Juliet Usher-Smith left the room

Final outcome: Conditional support

Competition 46 stage 1 applications considered

2.1 NIHR204106: Non Invasive Ventilation Study (NIVIS)

Conflicts: Dr Rebecca Harmston left the room

Outcome: Invite to Stage 2

2.2 NIHR204033: Family Connections: A feasibility trial of a skills training programme for carers of patients with Borderline Personality Disorder

Conflicts: None

Outcome: Invite to Stage 2

2.3 NIHR204017: Detection of Torsion by Registrars in Training (DETORT). Point of Care Ultrasound as an add-on test to clinical assessment in patients presenting with suspected testicular torsion: a feasibility diagnostic test accuracy study

Conflicts: None

Outcome: This application was subsequently withdrawn by the applicants

2.4 NIHR204030: What are the barriers to health promotion advice delivered by staff working in urgent care and emergency departments? – promotED study

Conflicts: None

Outcome: Invite to Stage 2

2.5 NIHR204049: Optimising recovery for cardiac arrest survivors and their caregivers: the Cardiac Arrest Recovery Enablement and Self-management Support (CARESS) Study

Conflicts: Dr Toby Smith left the room

Outcome: Invite to Stage 2

2.6 NIHR204115: Margin ACcentuation for resectable Pancreatic cancer using Irreversible Electroporation (MACPIE-II study): A Feasibility Multicentre Randomised Controlled Trial of Surgery with and without Margin Accentuation

Conflicts: Dr Wendi Qian left the room

Outcome: Invite to Stage 2

2.7 NIHR204053: Building a community of practice to identify barriers and priorities solutions to the right of access to healthcare for Travelling Communities

Conflicts: Dr Isabel Clare, Professor Julia Jones and Professor Andrew Bateman left the room

Outcome: Invite to Stage 2

2.8 NIHR204086: TCT-First for Respiratory Disease: A feasibility study evaluating the role of CT as the first-line investigation for patients presenting to primary care with symptoms and signs of lung cancer

Conflicts: None

Outcome: Rejected

2.9 NIHR204093: A double-blind multi-centre feasibility randomised controlled study of goal-directed haemodynamic therapy during renal transplantation

Conflicts: Dr Rebecca Harmston left the room

Outcome: Invite to Stage 2

2.10 NIHR204091: Advice for SLEep Education in Pregnancy (ASLEEP)

Conflicts: Dr Tracey Sach left the room Dr Rebecca Harmston remained out of the room. The Chair was assumed by Dr Juliet Usher-Smith

Outcome: Reject

Outcomes tables

The tables below display the mean score for each application that was assessed in the regional assessment committee meeting, and excludes applications which were rejected during the scrutiny and triage processes. The number of applications receiving each mean score are listed. The RfPB fundable range is 6-10, although a score of 6-10 does not guarantee funding or an invitation to Stage 2. In exceptional circumstances and with approval from the Programme Director, applications may be invited/funded which fall below the fundable range.

In exceptional circumstances, applications which fall below the fundable range may be invited to Stage 2 or recommended for funding by the Committee. The Programme Director reviews in detail any applications recommended for funding with a score below 7.

Competition 46 stage 1

ScoreRangeNumber of applications
9.0 - 10.0 Invited 0
8.0 - 8.9 Invited 1
7.0 - 7.9 Invited 4
6.0 - 6.9 Invited 2
6.0 - 6.9 Rejected 1
5.0 - 5.9 Rejected 1
4.0 - 4.9 Rejected 0
3.0 - 3.9 Rejected 0
2.0 - 2.9 Rejected 0
1.0 - 1.9 Rejected 0

Competition 45 stage 2

ScoreRangeNumber of applications
9.0 - 10.0 Fundable 0
8.0 - 8.9 Fundable 2
7.0 - 7.9 Fundable 1
6.0 - 6.9 Fundable 0
5.0 - 5.9 Rejected 1
4.0 - 4.9 Rejected 0
3.0 - 3.9 Rejected 0
2.0 - 2.9 Rejected 0
1.0 - 1.9 Rejected 0