Internet Explorer is no longer supported by Microsoft. To browse the NIHR site please use a modern, secure browser like Google Chrome, Mozilla Firefox, or Microsoft Edge.

Research for Patient Benefit - Competition 45 Stage 2 and Competition 46 Stage 1 minutes, London

Contents

Published: 12 April 2022

Version: 1 - April 2022

Print this document

Minutes for the Research for Patient Benefit (RfPB) programme London Regional Advisory Committee meeting to discuss Stage 2 applications to competition 45 and Stage 1 applications to competition 46.

Date and Location

Thursday 20 January 2022 Virtual Meeting

In attendance

Committee members

Professor Brian Davidson (Chair)
Dr Christopher Gale (Deputy Chair)
Dr Elizabeth Bancroft
Dr Jacqueline Birks
Dr Thomas Booth
Miss Eva Broeckelmann
Mr Martin Carroll
Dr Julia Chisholm
Professor Francesco D'Aiuto
Ms Mikaela Davies
Dr Anna De Simoni
Dr Martina Di Simplicio
Dr Johnny Downs
Professor Hemant Kocher
Dr Philip Kinghorn
Dr Dev Malhotra
Dr Rachel Philips
Dr Katie Sheehan
Professor Christina Victor
Dr Charlotte Warren-Gash

Secretariat

Mr Richard Foulsham (NIHR CCF)
Mr Ben Morgan (NIHR CCF)
Dr Jennie Hejdenberg (NIHR CCF)
Ms Lavpreet Ranjit (NIHR CCF)
Ms Ashley Mah (NIHR CCF)
Ms Sophie Tattersall (NIHR CCF)

Observers

Mrs Sarah Hughes (Schools)
Dr Naoimh McMahon (Schools)
Dr Peter J Lovell (RDS)

Apologies

Apologies were received from Catey Bunce.

Competition 45 stage 2 applications considered

1.1 NIHR203524: Being kind to ourselves: A feasibility randomised controlled trial of Compassion Focused therapy (CFT) to improve depression and anxiety in Dementia

Conflicts: Dr Philip Kinghorn left the room. Professor Christina Victor and Mr Martin Carroll were not in attendance. Dr Christopher Gale chaired the discussion

Final outcome: Conditional support

1.2 NIHR203610: A feasibility multicentre randomised controlled trial comparing Wide-awake Local Anaesthesia No Tourniquet (WALANT) versus General and Regional Anaesthesia for Flexor Tendon Repair (WAFER Trial)

Conflicts: Professor Brian Davidson, Dr Anna De Simoni and Professor Francesco D'Aiuto left the room. Mr Martin Carroll was not in attendance. Dr Christopher Gale chaired the discussion

Final outcome: Conditional support

1.3 NIHR203545: A MULTI-centre feasibility study to assess the use of 99m Tc-SestaMIBI SPECT/CT in the diagnosis of kidney tumours (MULTI-MIBI study)

Conflicts: Professor Brian Davidson, Dr Anna De Simoni and Professor Francesco D'Aiuto remained out of the room. Dr Christopher Gale chaired the discussion

Final outcome: Conditional support

1.4 NIHR203604: Eczema aNd Dermatitis – Implementing The Combined ApproacH (END-ITCH)

Conflicts: Dr Anna De Simoni remained out of the room. Dr Christopher Gale chaired the discussion

Final outcome: Conditional support

1.5 NIHR203566: Evaluating a brief novel treatment for COVID-related Post-Traumatic Stress Disorder (PTSD) in the Health and Social Care workforce: a pre-RCT preparatory study

Conflicts: Dr Elizabeth Bancroft and Professor Hemant Kocher left the room. Dr Christopher Gale chaired the discussion

Final outcome: Conditional support

1.6 NIHR203602: A feasibility study of brief Acceptance and Commitment Therapy (ACT) to support people presenting frequently to Emergency Departments with persistent pain

Conflicts: Miss Eva Broeckelmannleft the room. Dr Christopher Gale chaired the discussion

Final outcome: Reject

1.7 NIHR203552: Development of an Artificial Intelligence (AI) method for measuring eczema severity in all skin tones

Conflicts: Dr Rachel Philips left the room. Dr Christopher Gale chaired the discussion.

Final outcome: Reject

1.8 NIHR203601: Developing a minimal medication treatment choice for people with psychotic conditions

Conflicts: Professor Francesco D’Aiuto left the room. Dr Christopher Gale chaired the discussion

Final outcome: Reject

1.9 NIHR203526: Co-producing Recommendations To Support Early Diagnosis Of Colorectal Cancer In Community Pharmacy

Conflicts: Professor Francesco D’Aiuto remained out of the room. Dr Christopher Gale chaired the discussion

Final outcome: Conditional support

Competition 46 stage 1 applications considered

2.1 NIHR204088: Mobile telephone contingency management to encourage adherence to supervised medication among individuals receiving opioid agonist treatment: a feasibility study (TIES2)

Conflicts: Professor Francesco D’Aiuto remained out of the room. Dr Johnny Downs left the room. Mr Martin Carroll was not in attendance

Outcome: Invite to Stage 2

2.2 NIHR204129: MRI Assessment of Re-Innervated Muscle for Clinical Trials

Conflicts: Professor Francesco D’Aiuto remained out of the room

Outcome: Reject

2.3 NIHR203123: Systematic review & network meta-analysis of randomised controlled trials comparing antithrombotic drugs for cardiovascular risk reduction in patients with lower limb peripheral arterial disease

Conflicts: None

Outcome: Invite to Stage 2

2.4 NIHR204109: A randomised feasibility study of standard face-to face group X-PERT patient education versus digital and virtual X-PERT patient education for patients with Type 2 Diabetes

Conflicts: None

Outcome: Invite to Stage 2

2.5 NIHR204139: Reducing treatment burden in Atrial fibrillation using experience-based co-design

Conflicts: None

Outcome: Reject

2.6 NIHR204136: A pilot study to investigate changes to pelvic floor function following robotic-assisted radical prostatectomy using Multiple Array Probe Leiden (MAPLe) and MRI-based urethral sphincter assessment: The MAPLeMRI Study

Conflicts: None

Outcome: Reject

2.7 NIHR204120: The development and evaluation of a crisis-focused psychosocial intervention for people who have experience of complex emotional needs: A feasibility Randomised Controlled Trial (RCT)

Conflicts: Professor Francesco D'Aiuto, Dr Johnny Downs, Miss Eva Broeckelmann and Dr Rachel Philips left the room

Outcome: Invite to Stage 2

2.8 NIHR204087: PROMICE: Exploring the implementation of Patient-Reported Outcome Measures In routine Cancer Care through an equity lens

Conflicts: Dr Elizabeth Bancroft left the room. Dr Christopher Gale chaired the meeting

Outcome: Reject

2.9 NIHR204011: OsteoPorosis Tailored digital Intervention for Improving SElf-management (OPTImISE study)

Conflicts: None

Outcome: Invite to Stage 2

2.10 NIHR204142: Using MyHabeats -an mHealth (mobile Health) application- to support weight management and quality of life in patients after bariatric surgery: a randomised, controlled trial

Conflicts: Dr Martina Di Simplicio left the room

Outcome: Reject

Outcomes tables

The tables below display the mean score for each application that was assessed in the regional assessment committee meeting, and excludes applications which were rejected during the scrutiny and triage processes. The number of applications receiving each mean score are listed. The RfPB fundable range is 6-10, although a score of 6-10 does not guarantee funding or an invitation to Stage 2. In exceptional circumstances and with approval from the Programme Director, applications may be invited/funded which fall below the fundable range.

In exceptional circumstances, applications which fall below the fundable range may be invited to Stage 2 or recommended for funding by the Committee. The Programme Director reviews in detail any applications recommended for funding with a score below 7.

Competition 46 stage 1

ScoreRangeNumber of applications
9.0 - 10.0 Invited  0
8.0 - 8.9 Invited
7.0 - 7.9 Invited 0
6.0 - 6.9 Invited 1
5.0 - 5.9 Invited
4
5.0 - 5.9 Rejected 1
4.0 - 4.9 Rejected 4
3.0 - 3.9 Rejected 0
2.0 - 2.9 Rejected
1.0 - 1.9 Rejected  0

Competition 45 stage 2

ScoreRangeNumber of applications
9.0 - 10.0 Fundable
8.0 - 8.9 Fundable 1
7.0 - 7.9 Fundable
6.0 - 6.9 Fundable 0
5.0 - 5.9 Rejected 0
4.0 - 4.9 Rejected 3
3.0 - 3.9 Rejected
2.0 - 2.9 Rejected
1.0 - 1.9 Rejected