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Research for Patient Benefit Programme - Competition 38 Stage 2 and Competition 39 Stage 1 Minutes - East of England

 

Contents

Date and location:

held on Wednesday 18 September 2019 at Girton College, University of Cambridge, Huntingdon Road, Cambridge CB3 0JG

In attendance:

Dr Stephen Barclay (Chair)
Dr Isabel Clare
Professor Diana Gorog
Dr Rebecca Harmston
Lisa Irvine
Professor Christina Jerosch-Herold
Dr Julia Jones
Dr Anne Killett
Professor Susan Kirk
Dr Aris Perperoglou
Professor Carl Philpott
Dr Wendi Qian
Dr Peter Richmond
Dr Murray Smith
Dr Ewen Speed
Mrs Hilary Stobart
Dr Juliet Usher-Smith
Dr Ceri Wilson


Mr Simon Goodwin (NIHR CCF)
Miss Lilian Tomlinson (NIHR CCF)
Mr Ben Morgan (NIHR CCF)
Miss Saida Sherif (NIHR CCF)
Professor Sue Ziebland (Programme Director)
Dr Brian Crosbie (Observer – NIHR RDS East Midlands)
Dr Ruth Knight (Observer – NIHR RDS South Central)
Dr Gurdeep Sagoo (Observer – NIHR RDS Yorkshire and The Humber)

 Apologies were received from Professor Susan Kirk, Lisa Irvine, Dr Ewen Speed, Dr Robbie Duschinsky

 

Competition 38 Stage 2 applications considered

NIHR200796: What is the best second line therapy for people aged 65 years or over with type 2 diabetes?: systematic review and network meta-analysis

Conflicts: None

Final outcome: Conditional support 

NIHR200784: Evaluating Chronic Pain in Autosomal Dominant Polycystic Kidney Disease using a Patient-Centred Approach to Data Collection and Synthesis: A National Prospective Observational Study (EASE-PKD)

Conflicts: Dr Wendi Qian left the room

Final outcome: Conditional support

 

Competition 39 Stage 1 applications considered

NIHR201079: “Just walk it”: randomised controlled trial of a brief advice leaflet and use of the Active10 app to increase daily step count in mothers who had high blood pressure in pregnancy

Conflicts: None

Outcome: Invite to Stage 2

NIHR201124: Combining Mandibular advancement therapy with CPAP: effects on tolerability and adherence. The COMPETE Trial: an adaptive 2x2 randomised crossover trial comparing treatment with Continuous Positive Airway Pressure (CPAP) to CPAP + Mandibular Advancement Device (MAD) to ascertain whether combination CPAP-MAD therapy significantly reduces CPAP pressure requirements, improves tolerance to treatment and adherence to therapy (i.e. compliance)

Conflicts: None

Outcome: Invite to Stage 2

NIHR201060: Testing the feasibility and acceptability of case-finding and subsequent comprehensive geriatric assessment intervention for older people with HIV with frailty

Conflicts: None

Outcome: Invite to Stage 2

NIHR201115: Using experience-based co-design to develop a framework for a new national approach to improving the care of people living with HIV who have other long-term medical conditions

Conflicts: None

Outcome: Invite to Stage 2

NIHR201097: Rationalising AntiPsychotic treatment in adults with Intellectual Disabilities (RAPID)

Conflicts: Dr Isabel Clare left the room

Outcome: Invite to Stage 2

NIHR201121: Addressing the problem of long-term use of antidepressants among patients in primary care: Feasibility study of two de-prescribing interventions, including a novel cognitive training app

Conflicts: Dr Stephen Barclay and Dr Juliet Usher-Smith left the room, Professor Christina Jerosch-Herold assumed the Chair.

Outcome: Reject

NIHR201073: Reducing shoulder pain in wheelchair users with scapular focused exercises: a feasibility study

Conflicts: None

Outcome: Reject

NIHR201148: Developing novel blood and urinary bone turnover markers to aid in the management of osteomyelitis in the diabetic foot

Conflicts: Professor Christina Jerosch-Herold, Professor Carl Philpott and Dr Anne Killett left the room

Outcome: Reject

NIHR201077: The FRAIL-T2 study: developing outcome measures for frail major trauma patients

Conflicts: None

Outcome: Reject

NIHR201022: A randomised controlled trial assessing the effectiveness of a potentially scalable educational intervention: Health 4LGBTi, on the Knowledge, Attitudes and Practice Competency (self-efficacy) of medical and nursing students and junior doctors in relation to their LGBTi patients

Conflicts: None

Outcome: Reject

NIHR201085: Implementation of flash glucose monitoring in four paediatric diabetes clinics – before and after study to produce real world evidence of patient benefit

Conflicts: None

Outcome: Invite to Stage 2

NIHR201040: The WONDER Study: HIV in Women, bOne miNeral Density, fracturE and frailty: a mixed methods study to assess knowledge and concerns about low bone mineral density in women living with HIV

Conflicts: None

Outcome: Invite to Stage 2

NIHR201082: Pelvic FLoor EXercises and health awareness for the wellbeing of Young women: The PFLEXY study

Conflicts: None

Outcome: Reject

NIHR201128: Reducing alcohol-exposed pregnancies

Conflicts: Dr Murray Smith left the room

Outcome: Invite to Stage 2

NIHR201164: Does Seasonal Variation Affect The Risk Of Surgical Site Infection In Primary Hip And Knee Replacements in England? An Exploratory Prospective Cohort Study

Conflicts: None

Outcome: Reject

 

 

Outcomes table for C38 Stage 2 and C39 Stage 1

This table displays the mean score for each application that was assessed in the regional assessment committee meeting, and excludes applications that were rejected during the scrutiny and triage processes. Applications are listed according to mean score and outcome. The RfPB fundable range is 6-10 although a score of 6-10 does not guarantee funding. In exceptional circumstances and with approval from the Programme Director, applications may be invited/funded which fall below the fundable range.

 

  Fundable range Rejected range
Score 10 9 8 7 6 5 4 3 2 1
Stage 2                    

 

  Fundable range Rejected range
Score 10 9 8 7 6 5 4 3 2 1
Stage 1