Minutes for the Research for Patient Benefit (RfPB) programme London Regional Advisory Committee meeting to discuss Stage 2 applications to competition 38 and Stage 1 applications to competition 39.
Date and location
Thursday 26 September 2019 at LGC Ltd, Grange House, 15 Church Street, Twickenham TW1 3NL
In attendance
Funding committee members
Professor Brian Davidson (Chair)
Dr Julie Barber
Dr Lindsay Bearne
Dr Catey Bunce
Dr Marta Buszewicz
Ms Mikaela Davies
Dr Chris Gale
Professor Hemant Kocher
Ms Debra Lennard
Dr Brynmor Lloyd-Evans
Professor Nicola Pavese
Dr Mark Pennington
Dr Cath Taylor
Professor Shakila Thangaratinam
RfPB secretariat
Dr Samantha Gan (NIHR CCF)
Miss Yvette Arku-Nelson (NIHR CCF)
Mrs Nishita Nair (NIHR CCF)
Professor Sue Ziebland (Programme Director)
Dr Sabina Hurlbert (Observer – NIHR RDS South East)
Miss Sabeena Subba PPI CCF
Ms Judy Johnson-Smith Admin CCF
Mr Martin Caroll Public Member
Apologies
Apologies were received from Dr Victoria Serra-Sastre, Dr Channa Jayasena, Professor Beth Grunfeld, Dr Martina Di Simplicio and Mrs Lilu Wheeler
Competition 38 Stage 2 applications considered
NIHR201175: Shortening Duration of Untreated Illness in First Episode Eating Disorders: Development and Randomised Controlled Feasibility Trial of a Smartphone-Friendly Multi-Modal Decision Making Tool (FREED-M) to Improve Help-Seeking
Conflicts: Dr Catey Bunce and Dr Mark Pennington left the room
Final outcome: Conditional support
NIHR200794: The True Analgesic Efficacy of Burst Spinal Cord Stimulation in the Management of Failed Back Surgery Syndrome: A Multicentre, Randomised, Double-Blind, Sham-Controlled Study (TRU-BURST)
Conflicts: None
Final outcome: Reject
NIHR200756: Using Genetics to Personalise Antipsychotic Treatment
Conflicts: Dr Julie Barber, Dr Brynmor Lloyd- Evans and Dr Mark Pennington left the room
Final outcome: Conditional support
NIHR200765: Videoendoscopic radical inguinal lymphadenectomy versus open radical inguinal lymphadenectomy in patients with penile cancer: a feasibility randomised controlled trial
Conflicts: Dr Julie Barber remained out of the room, Professor Brian Davidson and Professor Hemant Kocher left the room.
Final outcome: Conditional support
NIHR200714: Easing primary to secondary school transition for children with autism: a feasibility randomised controlled trial
Conflicts: Dr Catey Bunce, Dr Mark Pennington and Dr Chris Gale left the room
Final outcome: Reject
NIHR200773: Empowering Parents Empowering Communities-Recovery (EPEC-R): A feasibility randomised control trial of a medium-intensity intervention for parents with severe personality difficulties
Conflicts: None
Final outcome: Reject
Competition 39 Stage 1 applications considered
NIHR201017: Patient-specific titration of mechanical ventilation via electrical impedance tomography in spontaneously-breathing patients with the acute respiratory distress syndrome: a randomised controlled trial
Conflicts: None
Outcome: Reject
NIHR201172: Prophylactic Closed Incision Negative Pressure Wound Therapy on Abdominal Wounds - Clinical and Economic Perspectives: A Multi-centre Randomised Trial
Conflicts: None
Outcome: Reject
NIHR201048: Electronic Activity Monitors to predict cancer patient outcomes in phase I drug trials - developing a tool to help better selection of patients for drug trials
Conflicts: None
Outcome: Reject
NIHR201027: Brief Advice and Biofeedback to help Reduce Alcohol consumption
Conflicts: Dr Brynmor Lloyd-Evans, Dr Marta Buszewicz, and Dr Julie Barber left the room
Outcome: Invite to Stage 2
NIHR201139: A Randomised Trial Assessing the Safety and Efficacy of Collateral based administration of adult autologous bone marrow cell administration in patients with chronic pain due to Refractory Angina - (REGENERATE-CobRA Trial)
Conflicts: None
Outcome: Reject
NIHR201145: What is the risk of thoracic aortic dissection and aortic events in moderately sized thoracic aortas?
Conflicts: None
Outcome: Reject
NIHR201161: A Prospective Randomised Placebo Controlled Trial on Prophylactic Endoscopic Clipping of Colonic Diverticula (PECoD)
Conflicts: Dr Mark Pennington left the room
Outcome: Invite to Stage 2
NIHR201144: Elicitation of patient preferences to generate a novel decision support tool for shared decision making in the management of strictures in Crohn’s disease
Conflicts: None
Outcome: Reject
NIHR201131: Comparing the effectiveness of website based and face to face Cognitive Behavioural Therapy to treat insomnia (CBTi) in Persons Living With HIV (PLWH): A randomised controlled trial
Conflicts: Professor Brian Davidson left the room
Outcome: Reject
NIHR201030: The use of computer-assisted therapy (AVATAR therapy) to reduce the power of the eating disorder voice in patients with anorexia nervosa: a feasibility study
Conflicts: Dr Catey Bunce left the room
Outcome: Invite to Stage 2
NIHR201021: C Pain Away': The development of cancer-pain education guidance for patients from Black Caribbean, Black African and Black 'other' communities in south east London and the health professionals caring from them
Conflicts: None
Outcome: Invite to Stage 2
NIHR201160: A Feasibility Study to Assess the Practicality of Performing a Multi-Centre Prospective Research Study Comparing Digital Colposcopy With Dynamic Spectral Imaging to Standard Colposcopy in Patients Referred from HPV Primary Screening
Conflicts: Dr Mark Pennington and Dr Catey Bunce left the room
Outcome: Invite to Stage 2
Outcomes tables
This table displays the mean score for each application that was assessed in the regional assessment committee meeting, and excludes applications that were rejected during the scrutiny and triage processes. Applications are listed according to mean score and outcome. The RfPB fundable range is 6-10 although a score of 6-10 does not guarantee funding. In exceptional circumstances and with approval from the Programme Director, applications may be invited/funded which fall below the fundable range.
Competition 38 Stage 2
| Score | Range | Number of applications |
|---|---|---|
| 10 | Fundable | 0 |
| 9 | Fundable | 0 |
| 8 | Fundable | 0 |
| 7 | Fundable | 0 |
| 6 | Fundable | 3 |
| 5 | Rejected | 2 |
| 4 | Rejected | 1 |
| 3 | Rejected | 0 |
| 2 | Rejected | 0 |
| 1 | Rejected | 0 |
Competition 39 Stage 1
| Score | Range | Number of applications |
|---|---|---|
| 10 | Fundable | 0 |
| 9 | Fundable | 0 |
| 8 | Fundable | 0 |
| 7 | Fundable | 1 |
| 6 | Fundable | 4 |
| 5 | Rejected | 0 |
| 4 | Rejected | 4 |
| 3 | Rejected | 2 |
| 2 | Rejected | 1 |
| 1 | Rejected | 0 |