Minutes for the Research for Patient Benefit (RfPB) programme East Midlands Committee meeting to discuss Stage 2 applications to competition 39 and Stage 1 applications to competition 40.
Date and location
Meeting held Tuesday 28 January 2020 at Imago at Loughborough Ltd, Holywell Park, Loughborough University, Loughborough, Leicestershire LE11 3TD.
In attendance
Committee members
Professor Roshan das Nair (Chair)
Professor Jon Arcelus
Mr Chris Bainbridge
Professor Matthew Bown
Dr Clare Gillies
Dr Adam Gordon
Mr Trevor Jones
Dr Paul Leighton
Dr Nicola Macintosh
Professor Richard Morriss
Ms Pamela Rees
Professor Nicholas Selby
Dr Adam Wagner
Mr David Ward
Dr Nicola Wright
Apologies
Apologies were received from Mrs Cassandra Brookes
Secretariat
Mr Francesco Sciammarella (NIHR Central Commissioning Facility [CCF])
Ms Fardawza Ahmed (NIHR CCF)
Dr Jennie Hejdenberg (NIHR CCF)
Professor Sarah Armstrong (Research Design Service for the East Midlands)
Competition 39 Stage 2 applications considered
NIHR201018: Randomised, double-blind, placebo controlled multi-centre study to assess the efficacy, tolerability and safety of Enterosgel in the treatment of faecal incontinence and diarrhoea
Conflicts:None
Final outcome: Reject
NIHR201146: Does knowledge of liver fibrosis affect high risk drinking behaviour (KLIFAD)? A feasibility randomised controlled trial.
Conflicts: Professor Jon Arcelus, Dr Paul Leighton, Professor Roshan das Nair, Dr Nicola Wright and Professor Richard Morriss left the room. Dr Nick Selby assumed the chair.
Final outcome: Conditional support
NIHR201118: Feasibility study comparing once-daily fluticasone furoate/vilanterol vs.twice-daily fluticasone propionate/salmeterol in adolescents with poorly controlled asthma
Conflicts: None
Final outcome: Reject
NIHR201064: Early Self-Management Support for painful Temporomandibular Disorders (TMD): a co-production study (EaSE TMD study)
Conflicts: Dr Nicola Mackintosh left the room
Final outcome: Reject
NIHR201587: A qualitative exploration of patient experience and pathways in people with Myeloproliferative Neoplasms associated Splanchnic Vein Thrombosis (MPN-SVT)
Conflicts: None
Final outcome: Reject
NIHR201113: Perinatal mental health in late pre-term fetal growth restriction. A nested cohort study in the TRUFFLE 2 randomised study
Conflicts: None
Final outcome: Reject
NIHR201091: Measuring and improving the health and quality of healthcare for people on probation: Developing data collection and quality indicators
Conflicts: Dr Paul Leighton and Mr David Ward left the room.
Final outcome: Conditional support
NIHR201075: “What happens to me if...?” Deprescribing medication in people with long-term health conditions: a systematic review focusing on patient-centred outcomes
Conflicts: None
Final outcome: Reject
Competition 40 Stage 1 applications considered
NIHR201574: A randomised control trial evaluating the effectiveness of Serenity Integrated Mentoring (SIM) compared to Treatment as Usual
Conflicts: None
Outcome: Reject
NIHR201572: An automated system for quality assurance of ultrasound measurements used in the monitoring of fetal growth
Conflicts: None
Outcome: Reject
NIHR201578: Health Inequalities in kiDney Disease: mEeting the urgent need to identify Early disease in high risk commuNities (HIDDEN): A feasibility study
Conflicts: Dr Nick Selby left the room.
Outcome: Invite to Stage 2
NIHR201571: Identifying procedure adjusted quality indicators for upper gastrointestinal endoscopy from systematic review and multivariate analysis of cohorts with post endoscopy upper gastrointestinal cancer in the national endoscopy database
Conflicts: None
Outcome: Invite to Stage 2
NIHR201577: Feasibility study of the use of electrical muscle stimulation in a group of older frail patients hospitalised with an acute illness.
Conflicts: None
Outcome: Invite to Stage 2
NIHR201460: Accelerated cardiovascular magnetic resonance in coronary artery disease
Conflicts: Professor Matthew Bown left the room.
Outcome: Invite to Stage 2
NIHR201566: A Novel Insomnia intervention via Telemedicine for Irritable Bowel Syndrome (NITE-IBS)
Conflicts: None
Outcome: Reject
NIHR201512: Introducing home monitoring to patients and embedding adherence management in the clinic - A pilot feasibility study to promote adherence in paediatric kidney transplantation.
Conflicts: None
Outcome: Reject
NIHR201580: Feasibility study for the use of autologous bone marrow cells in the treatment of refractory angina to alleviate symptoms and improve quality of life.
Conflicts: None
Outcome: Reject
NIHR201575: Improving response rates to clinical trial recruitment in asthma
Conflicts: Professor Jon Arcelus left the room.
Outcome: Reject
Outcomes tables
This table displays the mean score for each application that was assessed in the regional assessment committee meeting, and excludes applications that were rejected during the scrutiny and triage processes. Applications are listed according to mean score and outcome. The RfPB fundable range is 6-10 although a score of 6-10 does not guarantee funding. In exceptional circumstances and with approval from the Programme Director, applications may be invited/funded which fall below the fundable range.
C39 Stage 2
| Score | Range | Number of applications |
|---|---|---|
| 10 | Fundable | 0 |
| 9 | Fundable | 0 |
| 8 | Fundable | 1 |
| 7 | Fundable | 0 |
| 6 | Fundable | 1 |
| 5 | Rejected | 0 |
| 4 | Rejected | 1 |
| 3 | Rejected | 2 |
| 2 | Rejected | 2 |
| 1 | Rejected | 0 |
C40 Stage 1
| Score | Range | Number of applications |
|---|---|---|
| 10 | Fundable | 0 |
| 9 | Fundable | 0 |
| 8 | Fundable | 0 |
| 7 | Fundable | 3 |
| 6 | Fundable | 1 |
| 5 | Rejected | 1 |
| 4 | Rejected | 1 |
| 3 | Rejected | 3 |
| 2 | Rejected | 1 |
| 1 | Rejected | 0 |