Minutes for the Research for Patient Benefit (RfPB) programme South East and Central Regional Advisory Committee meeting to discuss applications Stage 2 applications to competition 39 and Stage 1 applications to competition 40.
Date and location
Held on Wednesday 22 January 2020 at ETC Venues, Avonmouth House, 6 Avonmouth Street, London SE1 6NX
In attendance
Committee members
Professor Carrie Llewellyn (Chair)
Mrs Wendy Blunden
Ms Nadia Brookes
Ms Rosemary Greenwood
Dr Mark Hayward
Professor Julia Hippisley-Cox
Dr Christina Jones
Miss Alison Provins
Profesor Najib M Rahman
Professor Simon Skene
Dr James Sheppard
Professor Ian Swaine
Mr David Turner
Dr Dawn-Marie Walker
Dr Peter Worsley
Mr Keith Wyncoll
Apologies
Apologies were received from Professor Daniel Freeman, Professor Michael Calnan, Mrs Ann-Marie Towers, Professor Simon Coulton and Professor Stephen Bremner.
Secretariat
Dr Laura Tornatore (NIHR Central Commissioning Facility [CCF])
Dr Rifat Mahbub (NIHR CCF)
Mr Ben Morgan (NIHR CCF)
Miss Lilian Tomlinson (NIHR CCF)
Dr Isabel Reading (Research Design Service [RDS] South Central)
Dr Sophie Hyndman (RDS South Central)
Professor Jorg Huber (RDS South East)
Professor Heather Gage (RDS South East)
Professor Roshan das Nair (East Midlands Chair)
Competition 39 Stage 2 applications considered
NIHR201588: Development Of a haemophiLia PHysiotherapy INtervention for optimum musculoskeletal health in children (DOLPHIN-II) - a randomised controlled trial
Conflicts: Professor Ian Swaine
Final outcome: Conditional Support
NIHR201031: Anti-TNF (Adalimumab) injection for the treatment of adults with frozen shoulder during the pain-predominant phase: a multi-centre, randomised, double blind, parallel group, feasibility study
Conflicts: None
Final outcome: Conditional Support
NIHR201093: Evaluation of the feasibility of a RCT of Empowered Conversations: a training to enhance relationships and communication between family carers and people living with dementia
Conflicts: None
Final outcome: Conditional Support
NIHR201032: A qualitative investigation of attitudes towards infant feeding among new mothers living with HIV in the UK.
Conflicts: Professor Carrie Llewellyn, Miss Alison Provins and Dr James Sheppard left the room. Professor Simon Skene assumed the chair.
Final outcome: Conditional Support
NIHR201153: A feasibility study for two simultaneous randomised controlled trials to compare the effectiveness of two techniques for managing pain in upper and lower tooth extractions.
Conflicts: Professor Carrie Llewellyn remained out of the room. Ms Rosemary Greenwood left the room.
Final outcome: Reject
NIHR201020: Brinzolamide eye-drops to treat nystagmus: A feasibility study and Core Outcome Set (COS) evaluation prior to a planned RCT
Conflicts: Dr Dawn-Marie Walker and Dr Peter Worsley left the room.
Final outcome: Reject
NIHR201036: REST: A prospective randomised feasibility study assessing the impact of a tailored sleep intervention in patients undergoing total knee replacement
Conflicts: Professor Carrie Llewellyn and Ms Rosemary Greenwood left the room. Professor Simon Skene assumed the chair.
Final outcome: Conditional Support
Competition 40 Stage 1 applications considered
NIHR201542: A multicentre randomised controlled trial (RCT) of a self-help cognitive behavioural therapy (CBT) intervention to reduce the impact of hot flush and night sweat (HFNS) symptoms in men with prostate cancer undergoing androgen deprivation therapy (ADT): MANaging symptoms during prostate CANcer treatment (MANCAN2)
Conflicts: Dr Dawn-Marie Walker and Dr Peter Worsley left the room.
Outcome: Invite to Stage 2
NIHR201473: SPiRIT (Shoulder Pain: Randomised trial of Injectable Treatments) A randomised feasibility and pilot study of Autologous Protein Solution (APS) vs Corticosteroids for treating subacromial shoulder pain
Conflicts: Professor Najib Rahman left the room.
Outcome: Invite to Stage 2
NIHR201564: Implementation of two-stage screening programme for Vasa Praevia: A prospective multi-site feasibility study (IMPROVE)
Conflicts: Ms Nadia Brookes and Professor Ian Swaine left the room.
Outcome: Reject
NIHR201470: Development and evaluation of an online decision aid on disclosure and help-seeking for health problems among health professionals
Conflicts: None
Outcome: Reject
NIHR201573: A feasibility study for an effectiveness evaluation of care and support planning for people with multimorbidity - the MaxWELL intervention
Conflicts: Ms Rosemary Greenwood and Professor Julia Hippisley-Cox left the room.
Outcome: Reject
NIHR201547: QUANtifying aTrIal Fibrillation burden using consumer technologY - QUANTIFY-AF
Conflicts: Professor Julia Hippisley-Cox remained out of the room. Dr James Sheppard, Mr David Turner and Dr Peter Worsley left the room.
Outcome: Reject
NIHR201491: Can hydrotherapy improve physical function, participation and activity levels in lower limb amputees: a feasibility study
Conflicts: None
Outcome: Reject
NIHR201499: Improving the collection of long-term outcome data to support patients to stay well following treatment in Improving Access to Psychological Therapies (IAPT) services: A feasibility study using the 'Paddle' therapy support app
Conflicts: Professor Julia Hippisley-Cox and Miss Alison Provins left the room.
Outcome: Reject
NIHR201558: The BCAE Study: Best Care for Abdominal Emergencies
Conflicts: None
Outcome: Invite to Stage 2
NIHR201516: Communicating Safety Netting advice for early diagnosis of cancer in primary care
Conflicts: Ms Rosemary Greenwood, Professor Julia Hippisley-Cox, Dr James Sheppard and Mr David Turner left the room.
Outcome: Reject
NIHR201537: The incidence, long term outcomes, complications and costs associated with shoulder injections
Conflicts: Mr David Turner remained out of the room. Professor Najib Rahman left the room.
Outcome: Reject
NIHR201569: Improving breast cancer survival by benchmarking breast cancer surgery in England
Conflicts: Professor Julia Hippisley-Cox and Dr James Sheppard left the room.
Outcome: Reject
NIHR201524: Could the concept of ‘kidney age’ improve doctor-patient communication and reduce unnecessary worry? A qualitative study testing patient acceptability of new clinical language for decreased kidney function
Conflicts: Professor Julia Hippisley-Cox and Dr James Sheppard remained out of the room. Dr Sophie Hyndman and Professor Najib Rahman left the room.
Outcome: Reject
Outcomes tables
Funding Committees score applications on a range of 1-10. These tables displays the number of applications awarded each score in the committee meeting for Competition 39 Stage 2 and Competition 40 Stage 1. The tables exclude applications that were rejected during the scrutiny and triage processes, and no ranking within columns should be inferred.
RfPB will fund applications that score in the range of 6-10, although a score of 6-10 does not guarantee funding. In exceptional circumstances and with approval from the Programme Director, applications may be invited/funded that fall below the fundable range (scoring 1-5).
Competition 39 Stage 2
| Score | Range | Number of applications |
|---|---|---|
| 10 | Fundable | 0 |
| 9 | Fundable | 0 |
| 8 | Fundable | 0 |
| 7 | Fundable | 2 |
| 6 | Fundable | 3 |
| 5 | Rejected | 1 |
| 4 | Rejected | 1 |
| 3 | Rejected | 0 |
| 2 | Rejected | 0 |
| 1 | Rejected | 0 |
Competition 40 Stage 1
| Score | Range | Number of applications |
|---|---|---|
| 10 | Fundable | 0 |
| 9 | Fundable | 0 |
| 8 | Fundable | 0 |
| 7 | Fundable | 0 |
| 6 | Fundable | 3 |
| 5 | Rejected | 3 |
| 4 | Rejected | 7 |
| 3 | Rejected | 0 |
| 2 | Rejected | 0 |
| 1 | Rejected | 0 |