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Research for Patient Benefit Programme - Competition 42 Stage 2 and Competition 43 Stage 1 Minutes, West Midlands

Contents

Published: 06 April 2021

Version: 1.0 - January 2021

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Minutes of the Research for Patient Benefit (RfPB) programme West Midlands Regional Advisory Committee meeting to discuss stage 2 applications to competition 42 and stage 1 applications to competition 43.

Date and Location

Tuesday 19 January 2021, Virtual Meeting

In attendance

Funding committee

Dr Rebecca Kearney (Chair)
Professor Prithwish Banerjee
Dr Opeyemi Babatunde
Dr Milica Blagojevic-Bucknall
Professor Matthew Brookes
Professor Julie Bruce
Ms Lynne Carney
Professor Nachiappan Chockalingam
Dr Sarah Damery
Professor Thomas Dietrich
Professor David Fitzmaurice
Mr Adrian Gardner
Dr Francis Gilchrist
Dr Susan Hunter
Dr Steven Marwaha
Dr Katie Morris
Dr Katie Newby
Professor Thomas Pinkney
Ms Louise Rowan
Dr Alice Sitch
Dr Abd Tahrani
Dr Jane Warwick
Ms Helen Weatherly
Dr Simon White

Secretariat

Mrs Nishita Nair (NIHR CCF)
Dr Kasia Kuleszewicz (NIHR CCF)
Ms Lara Oh (NIHR CCF)
Mr Mathew Bolton (NIHR CCF)
Professor Sue Ziebland (Programme Director)

Observers

Dr Jonathan Mathers (RDS - WM)
Professor Neil Thomas (RDS - WM)

Apologies

Apologies were received from Dr Katie Morris, Professor Andy Turner, Professor Matthew Brookes, Dr Katie Newby and Professor David Fitzmaurice

Stage 2 applications considered

1.1 NIHR202289: A randomised controlled feasibility trial of a prehabilitation intervention in frail older people undergoing total hip or knee replacement

Conflicts: Professor Julie Bruce

 Outcome: Conditional support

1.2 NIHR202172: LearninG from Women’s ExpeRiences of Anal InContinencE after Vaginal Birth (GRACE)

Conflicts: Professor Julie Bruce, Dr Alice Sitch, Dr Jane Warwick, Professor Thomas Pinkney and Professor Rebecca Kearney. Dr Abd Tahrani assumed the chair.

 Outcome: Conditional support

1.3 NIHR202255: Should we ligate haemodialysis fistulas in patients once they have been transplanted successfully? A feasibility study

Conflicts: None

Outcome: Conditional support

1.4 NIHR202256: Early intervention with combined Graded Motor Imagery and Pain Neuroscience Education in acute trauma inpatients to improve long-term pain and disability: a pilot and feasibility randomised trial

Conflicts: Mr Adrian Gardner and Professor Thomas Pinkney

 Outcome: Reject

1.5 NIHR202268: Acronym: CLosure Against REpair (CLARE) external pilot trial
Obliterative (Colpocleisis) versus Reconstructive (Sacrospinous Fixation) pelvic organ prolapse (POP) Surgery- An External Pilot Trial to Evaluate the Feasibility of a Substantive Trial

Conflicts: Mr Adrian Gardner, Professor Thomas Pinkney, Dr Alice Sitch, Dr Francis Gilchrist, Miss Louise Rowan and Dr Sarah Damery

Outcome: Reject

1.6 NIHR202220: Breast Screening Atypia: Observational Analysis of Subsequent Development of Cancer using Sloane UK database (Sloane Atypia)

Conflicts: Dr Alice Sitch, Dr Jane Warwick, Professor Julie Bruce and Professor Rebecca Kearney. Professor Thomas Pinkney assumed the chair

Outcome: Conditional support

1.7 NIHR202850: Atosiban versus placebo in the treatment of late threatened preterm birth. APOSTEL VIII study

Conflicts: None

Outcome: Conditional support

Stage 1 applications considered

2.1 NIHR202810: A pilot study to assess the safety, effectiveness and practical utility of remote patient monitoring to guide the timing of valve intervention in patients with asymptomatic severe aortic stenosis (APRAISE-AS)

Conflicts: Professor Steven Marwaha, Dr Alice Sitch, Dr Sarah Damery, Mr Adrian Gardner, Dr Abd Tahrani, Professor Thomas Pinkney and Professor Prithwish Banerjee

Outcome: Invite to Stage 2

2.2 NIHR202780: Cervical screening for women with physical disabilities: barriers and solutions

Conflicts: Professor Steven Marwaha, Dr Sarah Damery, Dr Milica Blagojevic-Bucknall, Dr Simon White, Dr Opeyemi Babatunde and Dr Susan Hunter

Outcome: Reject

2.3 NIHR202790: Complementary and alternative medicine therapies for patients with malignant brain tumours: a systematic review of randomised controlled trials and network meta-analysis

Conflicts: Professor Julie Bruce

Outcome: Reject

2.4 NIHR202800: Measuring fatigue in Axial Spondyloarthritis (axSpA): refinement, application and evaluation of a new electronic patient-reported outcome measure (the Warwick Axial Spondyloarthritis Fatigue and Energy questionnaire (e-WASTEd)) in routine rheumatology practice

Conflicts: Professor Julie Bruce, Professor Steven Marwaha, Professor Jane Warwick, Dr Susan Hunter, Professor Prithwish Banerjee and Professor Rebecca Kearney. Professor Thomas Pinkney assumed the chair

Outcome: Invite to Stage 2

2.5 NIHR202824: Developing effective strategies to reduce COPD exacerbations: using qualitative research perspectives to learn from COVID-19 control measures and co-develop recommendations with patient, practice and policy stakeholders

Conflicts: Professor Steven Marwaha, Professor Thomas Dietrich, Dr Alice Sitch, Dr Sarah Damery, Dr Abd Tahrani and Professor Thomas Pinkney

Outcome: Reject

2.6 NIHR202816: Testing the acceptability of EarLy Surveillance for Autoimmune diabetes: The ELSA Study

Conflicts: Professor Steven Marwaha, Dr Alice Sitch, Dr Sarah Damery, Dr Abd Tahrani, Professor Thomas Pinkney and Mr Adrian Gardner

Outcome: Invite to Stage 2

2.7 NIHR202798: iMAgery focused therapy for PSychosis (iMAPS-2): A single blind randomised controlled trial

Conflicts: Ms Helen Weatherly

Outcome: Reject

2.8 NIHR202818: PREhabilitation for PAtients With Abdominal aoRtic anEurysms awaiting elective repair (PREP-AWARE). A feasibility randomised controlled trial

Conflicts: Professor Prithwish Banerjee, Professor Steven Marwaha, Professor Julie Bruce, Professor Jane Warwick and Professor Rebecca Kearney. Dr Abd Tahrani assumed the chair.

Outcome: Reject

2.9 NIHR202721: RIghts and CHoices for women with cerebral palsy (RICH study): A qualitative study to understand what works in the provision of their maternity care

Conflicts: Dr Sarah Damery

Outcome: Invite to Stage 2

2.10 NIHR202803: Exploring the feasibility of implementing a behaviour change digital health intervention (Gro Health App) to support weight loss, communication and continuity of care for patients who are referred to specialist obesity services

Conflicts: Professor Prithwish Banerjee, Professor Steven Marwaha, Professor Julie Bruce, Professor Jane Warwick, Mr Adrian Gardner and Professor Rebecca Kearney. Professor Thomas Pinkney assumed the chair.

Outcome: Reject

Outcomes tables

Funding Committees score applications on a range of 1-10. These tables display the number of applications awarded each score in the committee meeting. The tables exclude applications that were rejected during the scrutiny and triage processes, and no ranking within columns should be inferred.

RfPB will fund applications that score in the range of 6-10, although a score of 6-10 does not guarantee funding. In exceptional circumstances and with approval from the Programme Director, applications may be invited/funded that fall below the fundable range (scoring 1-5).

Competition 42 stage 1

ScoreRangeNumber of applications
10 Fundable  0
9 Fundable  0
8 Fundable  1
7 Fundable  1
6 Fundable  4
5 Rejected  1
4 Rejected  1
3 Rejected  1
2 Rejected  0
1 Rejected  0

Competition 42 stage 2

ScoreRangeNumber of applications
10 Fundable  0
9 Fundable  0
8 Fundable  2
7 Fundable  1
6 Fundable  2
5 Rejected  0
4 Rejected  1
3 Rejected  1
2 Rejected  0
1 Rejected  0