Minutes of the Research for Patient Benefit (RfPB) programme East Midlands Regional Advisory Committee meeting to discuss stage 2 applications to competition 42 and stage 1 applications to competition 43.
Date and Location
Tuesday 26 January 2021, Virtual Meeting
In attendance
Funding committee
Professor Roshan das Nair
Professor Jon Arcelus
Professor Matthew Bown
Mrs Cassandra Brookes
Dr Apostolos Fakis (Attended Stage 1 only)
Dr Clare Gillies
Dr Louise Jackson
Mr Trevor Jones
Professor Graham Law
Dr Paul Leighton
Professor Dileep Lobo
Dr Nicola Mackintosh
Professor Richard Morriss
Ms Pamela Rees
Miss Amanda Rudczenko
Professor Catherine Sackley
Professor Nicholas Selby
Professor Niro Siriwardena
Secretariat
Mr Francesco Sciammarella (NIHR CCF)
Dr Kasia Kuleszewicz (NIHR CCF)
Mr Ben Morgan (NIHR CCF)
Ms Katie Prangle (NIHR CCF)
Ms Ayesha Iqbal (NIHR CCF)
Observers
Prof Sarah Armstrong (RDS - EM)
Mr Martin Williams (RDS - EM)
Mr Alex Zabala Findley- Trainee Graduate
Ms Natalya Chapman -Trainee Graduate
Apologies
Apologies were received from Mr Chris Bainbridge, Dr Don Sharkey and Dr Joseph Manning
Stage 2 applications considered
1.1 NIHR202219: Clinical and cost-effectiveness of early patient-directed rehabilitation versus standard rehabilitation following total shoulder replacement: a multi-centre, unblinded, randomised controlled trial with nested qualitative study (RE-StART)
Conflicts: Professor Nicholas Selby, Dr Apostolos Fakis left the room and remained out for the duration of the Stage 2 applications
Outcome: Reject
1.2 NIHR202204: Living Healthy Lives: Exploring affects of growing older with cerebral palsy and use of healthcare services across the life course
Conflicts: Professor Roshan das Nair, Dr Paul Leighton, Mrs Cassandra Brookes, Dr Louise Jackson, Professor Catherine Sackley and Professor A. Niroshan Siriwardena, Professor Nicholas Selby assumed the Chair
Outcome: Conditional support
1.3 NIHR202195: Erector Spinae Plane blocks for the Early Analgesia of Rib fractures in trauma: a feasibility randomised controlled trial with embedded qualitative assessment (ESPEAR trial)
Conflicts: Professor Roshan das Nair, Dr Paul Leighton and Mrs Cassandra Brookes, Professor Nicholas Selby assumed the Chair
Outcome: Conditional support
1.4 NIHR202275: BIOSYM - A Multicentre, Feasibility, Randomised Controlled Trial Comparing Biological Matrices with Synthetic Meshes in Women Undergoing One Stage Implant Based Breast Reconstruction
Conflicts: Professor Nicholas Selby
Outcome: Reject
1.5 NIHR202197: The feasibility of Patient-Reported Outcome (PROM) and Experience Measure (PREM) collection for older people with frailty in the emergency care setting
Conflicts: Dr Nicola Mackintosh, Ms Pamela Rees, Professor Matthew Bown and Mrs Cassandra Brookes
Outcome: Reject
Stage 1 applications considered
2.1 NIHR202726: The role of ethnicity in opioid prescribing and health service use in the last three months of life: a population-based comparative cohort study of cancer patients
Conflicts: None
Outcome: Invite to Stage 2
2.2 NIHR202764: Is the naturally occurring prebiotic Lactoferrin an acceptable alternative to antibiotic tablets for women with bacterial vaginosis or thrush? The LISA (Lactoferrin InStead of Antibiotics) feasibility study.
Conflicts: Professor Catherine Sackley
Outcome: Invite to Stage 2
2.3 NIHR202774: Optimised Inhalers to Reduce COPD Exacerbation Re-Admissions and Mortality
Conflicts: None
Outcome: Invite to Stage 2
2.4 NIHR202829: Evidence-based management of gastro-oesophageal reflux in preterm infants: a mixed methods feasibility study
Conflicts: Professor Roshan das Nair, Professor Nicholas Selby, Dr Paul Leighton and Dr Apostolos Fakis. Mrs Cassandra Brookes assumed the Chair
Outcome: Reject
2.5 NIHR202848: eCARES electronic patient reported symptom control and advice in older adults with frailty: Development and feasibility field testing of a theoretically driven intervention
Conflicts: None
Outcome: Reject
2.6 NIHR202755: Personal mobile and wearable technology generated data analysis for depression monitoring
Conflicts: Professor Richard Morriss and Mrs Cassandra Brookes
Outcome: Reject
2.7 NIHR202777: A systematic review examining the non-pharmacological/surgical interventions of improving QoL, anxiety and depression in individuals with atrial fibrillation
Conflicts: Dr Apostolos Fakis, Dr Clare Gillies, Professor Matthew Bown and Mrs Cassandra Brookes
Outcome: Reject
2.8 NIHR202781: The association between medicines/vaccines commonly prescribed to older people and bullous pemphigoid: a UK population-based study.
Conflicts: Professor Roshan das Nair, Dr Paul Leighton, Professor Richard Morriss and Professor Dileep N Lobo. Professor Nicholas Selby assumed the Chair
Outcome: Invite to Stage 2
2.9 NIHR202812: Characterising the clinical care of children with unilateral hearing loss
Conflicts: Dr Paul Leighton, Dr Apostolos Fakis, Ms Pamela Rees and Mrs Cassandra Brookes
Outcome: Reject
2.10 NIHR202828: Barriers and facilitators of physical activity experienced by people with musculoskeletal pain: a realist synthesis of the literature with embedded co-design
Conflicts: Dr Paul Leighton, Dr Apostolos Fakis and Mrs Cassandra Brookes, Professor Roshan das Nair, Professor Richard Morriss, Professor Catherine Sackley. The Chair was assumed by Professor Nicholas Selby
Outcome: Reject
2.11 NIHR202841: Improving Appropriate Referrals to Secondary Care Kidney Services through the Kidney Failure Risk Equation
Conflicts: Mrs Cassandra Brookes Dr Nicola Mackintosh, Dr Clare Gillies and Professor Matthew Bown
Outcome: Reject
2.12 NIHR202804: Optimising walking exercise using music during Pulmonary Rehabilitation: Make every Step Count (MuSiC) feasibility trial
Conflicts: Mrs Cassandra Brookes, Dr Clare Gillies, Professor Roshan das Nair. Dr Paul Leighton assumed the Chair
Outcome: Reject
Outcomes tables
Funding Committees score applications on a range of 1-10. These tables display the number of applications awarded each score in the committee meeting. The tables exclude applications that were rejected during the scrutiny and triage processes, and no ranking within columns should be inferred.
RfPB will fund applications that score in the range of 6-10, although a score of 6-10 does not guarantee funding. In exceptional circumstances and with approval from the Programme Director, applications may be invited/funded that fall below the fundable range (scoring 1-5).
Competition 42 stage 2
| Score | Range | Number of applications |
|---|---|---|
| 10 | Fundable | 0 |
| 9 | Fundable | 0 |
| 8 | Fundable | 1 |
| 7 | Fundable | 1 |
| 6 | Fundable | 0 |
| 5 | Rejected | 1 |
| 4 | Rejected | 0 |
| 3 | Rejected | 2 |
| 2 | Rejected | 0 |
| 1 | Rejected | 0 |
Competition 43 stage 1
| Score | Range | Number of applications |
|---|---|---|
| 10 | Fundable | 0 |
| 9 | Fundable | 0 |
| 8 | Fundable | 0 |
| 7 | Fundable | 1 |
| 6 | Fundable | 3 |
| 5 | Rejected | 3 |
| 4 | Rejected | 0 |
| 3 | Rejected | 4 |
| 2 | Rejected | 1 |
| 1 | Rejected | 0 |