Minutes for the Research for Patient Benefit (RfPB) programme East of England Regional Advisory Committee meeting to discuss applications Stage 2 applications to competition 43 and Stage 1 applications to competition 44.
Date and Location
Friday 21 May 2021 Virtual Meeting
In attendance
Committee members
Professor Tracey Sach (Chair)
Dr Isabel Clare
Dr Robbie Duschinsky
Dr Rebecca Harmston
Professor Julia Jones
Dr Jacqueline Mitton
Professor Carl Philpott
Dr Wendi Qian
Dr Murray Smith
Dr Toby Smith
Dr Juliet Usher-Smith
Dr Ceri Wilson
Secretariat
Mr Simon Goodwin (NIHR CCF)
Dr Kasia Kuleszewicz (NIHR CCF)
Ms Lily Tomlinson (NIHR CCF
Ms Katie Prangle (NIHR CCF)
Professor Sue Ziebland (Programme Director)
Observers
Dr Annie Hawton (RDS SW)
Mrs Sarah Rhodes (RDS NW)
Dr Gysbert Fourie
Apologies
Apologies were received from Dr Anne Killett
Competition 43 stage 2 applications considered
1.1 NIHR202768: Formative research to inform the development of a smoking cessation intervention for childhood, adolescent and young adult cancer survivors
Conflicts: None
Final outcome: Conditional support
1.2 NIHR202769: Hairdressing salons to promote NHS online application to reduce under-diagnosis of cardiovascular risk factors among women in London’s deprived and ethnically diverse neighbourhoods: a feasibility study
Conflicts: None
Final outcome: Conditional support
1.3 NIHR202727: Management of pain and cachexia in pancreatic cancer: Systematic reviews of randomised controlled trials and network meta-analysis
Conflicts: None
Final outcome: Conditional support
1.4 NIHR202775: Paramedic initiation of Advance Care Plans for patients aged 65 years and over approaching the end of life (PARASOL)
Conflicts: None
Final outcome: Reject
1.5 NIHR202745: Making informed decisions before knee replacement: qualitative evidence base for a decision aid
Conflicts: None
Final outcome: Conditional support
Competition 44 stage 1 applications considered
2.1 NIHR203023: A systematic review of parents’/carers' needs, and interventions to support parents/carers of young people with mental health problems receiving mental health services: evidence synthesis with stakeholder engagement to provide practical recommendations
Conflicts: None
Outcome: Invite to Stage 2
2.2 NIHR203160: Predicting the 2- and 5-year risk of kidney failure for patients with chronic kidney disease in the United Kingdom: external validation and update of the Kidney Failure Risk Equation
Conflicts: None
Outcome: Invite to Stage 2
2.3 NIHR203024: Process evaluation of embedding the CoolCuddle intervention into neonatal intensive care units
Conflicts: None
Outcome: Invite to Stage 2
2.4 NIHR203053: Patient and clinician experiences of pre-hospital care for traumatic brain injury: an exploratory qualitative study and development of recommendations for best practice
Conflicts: Dr Ceri Wilson
Outcome: Reject
2.5 NIHR203092: Secondary analysis to explore the relative effectiveness of different approaches to assessing medication related anticholinergenic burden on the health of older people
Conflicts: Professor Carl Philpott, Professor Tracey Sach and Dr Toby Smith, Dr Juliet Usher-Smith assumed the Chair
Outcome: Reject
2.6 NIHR203026: Vertebral fracture clinical decision tool for older women with back pain (Vfrac) – a feasibility study
Conflicts: Dr Toby Smith
Outcome: Invite to Stage 2
2.7 NIHR203045: Improving Parental Engagement in Child Death Review
Conflicts: None
Outcome: Invite to Stage 2
2.8 NIHR203035: Comparing pharmacological and non-pharmacological interventions for adults with Attention-Deficit/Hyperactivity Disorder (ADHD): systematic review and network meta-analysis
Conflicts: Professor Julia Jones and Dr Toby Smith
Outcome: Invite to Stage 2
2.9 NIHR203141: ACCorD: Adhesive Capsulitis Corticosteroid or Dilation
Conflicts: Dr Toby Smith
Outcome: Invite to Stage 2
2.10 NIHR203039: What is the role of continuity of care in Integrated Care Systems, for older people with frailty in primary and community care settings: who needs it, when, why, how, in what circumstances, and to what extent? A realist review study
Conflicts: Dr Toby Smith
Outcome: Reject
2.11 NIHR203030: A culturally sensitive codesigned physical activity and sedentary behaviour intervention to support social, psychological and physical effects of breast cancer in South Asian women
Conflicts: Dr Murray Smith
Outcome: Reject
2.12 NIHR203139: An open-label, multi-centre, phase III randomised controlled trial to evaluate REtzius-sparing robot-assisted radical prostatectomy (RS-RARP) versus the Standard RARP (S-RARP) Technique Among prostate cancer patients at high Risk of post-operative urinary inconTinence (RESTART)
Conflicts: Dr Toby Smith
Outcome: Reject
2.13 NIHR203199: The feasibility of a sleep extension intervention to prevent Type 2 diabetes mellitus in people with habitual short sleep duration and pre-diabetes: The Sleep Extension and Maintenance in Pre-diabetes Randomised Feasibility trial (SEMPER-FI)
Conflicts: None
Outcome: Reject
Outcomes tables
The tables below display the mean score for each application that was assessed in the regional assessment committee meeting, and excludes applications which were rejected during the scrutiny and triage processes. The number of applications receiving each mean score are listed. The RfPB fundable range is 6-10, although a score of 6-10 does not guarantee funding or an invitation to Stage 2. In exceptional circumstances and with approval from the Programme Director, applications may be invited/funded which fall below the fundable range.
In exceptional circumstances, applications which fall below the fundable range may be invited to Stage 2 or recommended for funding by the Committee. The Programme Director reviews in detail any applications recommended for funding with a score below 7.
Competition 44 stage 1
| Score | Range | Number of Applications |
|---|---|---|
| 9-10 | Invited | 1 |
| 8 | Invited | 0 |
| 7 | Invited | 5 |
| 6 | Invited | 1 |
| 6 | Rejected | 1 |
| 5 | Rejected | 4 |
| 4 | Rejected | 1 |
| 3 | Rejected | 0 |
| 2 | Rejected | 0 |
| 1 | Rejected | 0 |
Competition 43 stage 2
| Score | Range | Number of Applications |
|---|---|---|
| 9-10 | Fundable | 0 |
| 8 | Fundable | 0 |
| 7 | Fundable | 3 |
| 6 | Fundable | 1 |
| 5 | Rejected | 0 |
| 4 | Rejected | 1 |
| 3 | Rejected | 0 |
| 2 | Rejected | 0 |
| 1 | Rejected | 0 |