Minutes for the Research for Patient Benefit (RfPB) programme London Regional Advisory Committee meeting to discuss applications Stage 2 applications to competition 43 and Stage 1 applications to competition 44.
Date and Location
Thursday 20 May 2021 Virtual Meeting
In attendance
Committee members
Professor Brian Davidson (Chair)
Dr Elizabeth Bancroft
Miss Eva Broeckelmann
Dr Catey Bunce
Mr Martin Carroll
Dr Julia Chisholm
Professor Francesco D'Aiuto
Ms Mikaela Davies
Dr Anna De Simoni
Dr Martina Di Simplicio
Dr Johnny Downs
Dr Chris Gale
Professor Hemant Kocher
Dr Philip Kinghorn
Dr Dev Malhotra
Dr Aidan O’Keeffe
Dr Katie Sheehan
Professor Christina Victor
Dr Charlotte Warren-Gash
Secretariat
Ms Tembi Huna (NIHR CCF)
Dr Jennie Hejdenberg (NIHR CCF)
Ms Saida Sherif (NIHR CCF)
Ms Tanya Dixey (NIHR CCF)
Observers
Ms Kate Bennett Eastley (RDS - SE)
Dr John Belcher (RDS - WM)
Dr Mark Lown (RDS - SC)
Competition 43 stage 2 applications considered
1.1 NIHR202748: Development of a core outcome set for clinical research on interventions for speech impairments in Stroke: COS-Speech
Conflicts: None
Final outcome: Conditional support
1.2 NIHR202744: Can Mandibular Advancement Device Treatment For Obstructive Sleep Apnoea Reduce Nocturnal Gastro-Oesophageal Reflux: A Feasibility Study
Conflicts: None
Final outcome: Conditional support
1.3 NIHR202758: Developing a Remotely Delivered Psychological Intervention to Treat Depression in Adolescents with Autism Spectrum Disorder
Conflicts: Dr Johnny Downs
Final outcome: Reject
1.4 NIHR202731: Ending long-term intensive treatment for borderline personality disorder: A mixed-methods evaluation of experiences and outcomes
Conflicts: Dr Martina Di Simplicio
Final outcome: Reject
1.5 NIHR203032: The co-design of a self-management programme for people with Antiphospholipid Syndrome
Conflicts: Dr Catey Bunce and Dr Katie Shehaan
Final outcome: Reject
1.6 NIHR202725: Rapid exome sequencing for the diagnosis of critically ill children in the NHS Genomic Medicine Service: Ensuring an equitable and effective parent and patient-centred service
Conflicts: Dr Anna De Simoni
Final outcome: Conditional support
1.7 NIHR203242: Time to Quit (T2Quit) A feasibility study of a tailored self-help text-smoking cessation intervention for smokers with Type 2 Diabetes (T2D)
Conflicts: Dr Anna De Simoni and Dr Catey Bunce
Final outcome: Reject
1.8 NIHR202743: ACT for Functional Cognitive Disorders - feasibility study
Conflicts: None
Final outcome: Conditional support
Competition 44 stage 1 applications considered
2.1 NIHR203170: Development and feasibility testing of an intervention to prevent potentially harmful skincare practices during infancy
Conflicts: Dr Catey Bunce, Dr Christopher Gale and Dr Martina Di Simplicio
Outcome: Invite to Stage 2
2.2 NIHR203152: A feasibility study comparing UroLIFT with Transurethral Resection of Prostate ahead of Radiotherapy in men with bladder outlet obstruction (CO-STAR)
Conflicts: Dr Elizabeth Bancroft, Dr Aidan O’Keeffe, Dr Catey Bunce
Outcome: Invite to Stage 2
2.3 NIHR203142: Shared decision making in gender diverse young people, their parents and clinicians in the Gender Identity Development Service (GIDS)
Conflicts: None
Outcome: Reject
2.4 NIHR203123: Adapting a smartphone-based rehabilitation programme for older adults living with and beyond cancer: a development study using Intervention Mapping
Conflicts: Professor Brian Davidson and Professor Hemant Kocher.
Outcome: Invite to Stage 2
2.5 NIHR203183: Endometriosis Fertility Index: A non-surgical approach
Conflicts: None
Outcome: Reject
2.6 NIHR203151: Exploring the feasibility of using Nasal High Flow (NHF) as a treatment for disabling and intractable breathlessness in patients with chronic Respiratory Disease (CRD)
Conflicts: Dr Francesco D’Aiuto
Outcome: Invite to Stage 2
2.7 NIHR203231: The Resolution of symptoms after Oesophago-Gastric resection (the RESTORE study)
Conflicts: Dr Catey Bunce
Outcome: Reject
2.8 NIHR203158: Investigating the effects of yoga for adults with cystic fibrosis (YOGA-CF)
Conflicts: None
Outcome: Invite to Stage 2
2.9 NIHR203150: Research into the Effectiveness of Biographical Films for Individuals with moderate-severe Dementia with an abbreviated My Life Films tool (REBIND 2): A feasibility study
Conflicts: None
Outcome: Reject
2.10 NIHR203168: Comparative safety and effectiveness of direct-acting oral anticoagulants in preventing stroke in extremes of weight patients with atrial fibrillation
Conflicts: Dr Charlotte Warren-Gash and Professor Francesco D’Aiuto
Outcome: Reject
2.11 NIHR203218: Understanding Patient Benefits Of Different Rhythm Control Strategies For Patients With Atrial Fibrillation In The United Kingdom
Conflicts: Dr Francesco D’Aiuto
Outcome: Reject
2.12 NIHR203204: Pilot randomised study of an exercise programme among pregnant women in London NHS Hospital
Conflicts: Dr Christopher Gale
Outcome: Reject
2.13 NIHR203175: An inflammation and infection point-of-care test for the prediction of chorioamnionitis in women at high risk of spontaneous preterm birth
Conflicts: Dr Christopher Gale and Catey Bunce
Outcome: Reject
Outcomes tables
The tables below display the mean score for each application that was assessed in the regional assessment committee meeting, and excludes applications which were rejected during the scrutiny and triage processes. The number of applications receiving each mean score are listed. The RfPB fundable range is 6-10, although a score of 6-10 does not guarantee funding or an invitation to Stage 2. In exceptional circumstances and with approval from the Programme Director, applications may be invited/funded which fall below the fundable range.
In exceptional circumstances, applications which fall below the fundable range may be invited to Stage 2 or recommended for funding by the Committee. The Programme Director reviews in detail any applications recommended for funding with a score below 7.
Competition 44 stage 1
| Score | Range | Number of applications |
|---|---|---|
| 9-10 | Invited | 0 |
| 8 | Invited | 1 |
| 7 | Invited | 1 |
| 6 | Invited | 1 |
| 5 | Invited | 2 |
| 4 | Rejected | 8 |
| 3 | Rejected | 0 |
| 2 | Rejected | 0 |
| 1 | Rejected | 0 |
Competition 43 stage 2
| Score | Range | Number of applications |
|---|---|---|
| 9-10 | Fundable | 0 |
| 8 | Fundable | 0 |
| 7 | Fundable | 3 |
| 6 | Fundable | 1 |
| 5 | Rejected | 3 |
| 4 | Rejected | 1 |
| 3 | Rejected | 0 |
| 2 | Rejected | 0 |
| 1 | Rejected | 0 |