Efficacy and Mechanism Evaluation (EME)

The Efficacy and Mechanism Evaluation Programme calls on the expertise, knowledge and opinion of a large number of people to ensure that the identification of research areas and funding decisions are chosen in a clear and fair way.

The EME Advisory Committee provides advice to the EME Programme Director on the scientific strategy for the programme.

The EME Funding Committee assesses outline and full proposals and makes funding decisions for the researcher-led workstream, and makes funding recommendations to the Department of Health for the commissioned workstream.

Members of EME Advisory Committees are required to declare any interests which conflict, or may be considered to conflict, with EME business, or may be perceived as influencing decisions made in the course of their work within the EME programme in line with the Conflicts of Interest Policy. All members are asked to complete the Register of Interest form (annually), which is intended to capture long term predictable interests that could be perceived to lead to conflicts of interest. These and other interests are judged on a case by case basis at individual meetings. View the Register of Interests for each EME programme advisory group.

Find out more about becoming a reviewer or current committee member opportunities.

EME Funding Committee 

Director (Interim Chair)Organisation
 Professor  Danny McAuley   Professor of Intensive Care, Queen's University of Belfast

Professor Danny McAuley is Professor of Intensive Care Medicine at the Wellcome-Wolfson Institute for Experimental Medicine, Queen's University of Belfast, and Consultant in Intensive Care Medicine at the Royal Victoria Hospital, Belfast.

His major interest is the Acute Respiratory Distress Syndrome (ARDS). His other current research interests include nosocomial infection, sepsis diagnostics, delirium in critical illness and interventions to enhance recovery from critical illness.

His other roles include Co-Director of Research for the UK Intensive Care Society. 

Professor Eric Alton (Deputy Chair) Professor of Gene Therapy and Respiratory Medicine, Imperial College London
Dr Simon Bond Senior Statistician from Cambridge Clinical Trials Unit, Addenbrooke’s Hospital Cambridge University Hospitals NHS Foundation Trust
Dr Louise Brown Senior Statistician, MRC Clinical Trials Unit, University College London
Professor Bill Deakin Professor of Psychiatry and Director NPU, Manchester University
Professor Janet Dunn Professor of Clinical Trials & Head of Cancer Trials, University of Warwick
Professor Carrol Gamble Reader Medical Statistics, University of Liverpool
Professor Paula Ghaneh Professor of Surgery, University of Liverpool, Honorary Consultant Surgeon in Hepatobiliary Surgery, Royal Liverpool University Hospital
Professor Fiona Gilbert Consultant Radiologist, Head of Department of Radiology at the University of Cambridge, Cambridge University Hospitals NHS Foundation Trust
Professor Jonathan Grigg Professor of Paediatric Respiratory and Environmental Medicine, Queen Mary University of London
Professor Ajit Lalvani Director of Tuberculosis Research Centre, National Heart and Lung Institute, Imperial College London
Professor Iain McInnes Professor of Experimental Medicine / Director of Research Institute, University of Glasgow
Professor Michael Nicholson Professor of Transplant Surgery, University of Cambridge
Mr Richard Parnell Public board member
Dr Richard Peck Head of Clinical Pharmacology, Roche Global; Roche Products Ltd. 
Professor John Petrie Professor of Diabetic Medicine, University of Glasgow
Professor Ruth Plummer Professor of Experimental Cancer Medicine, Newcastle University
Professor Rustam Salman Professor of Clinical Neurology & Honorary Consultant Neurologist, University of Edinburgh
Professor Robert Storey Professor and Honorary Consultant in Cardiology, Medical School, University of Sheffield
Professor Frank Sullivan Professor of Family and Community Medicine, University of St Andrews
Professor Steve Thornton Vice Principal (Health) and Executive Dean, Queen Mary University of London
Professor Mark Thursz Professor of Hepatology, Imperial College London and St Mary's Hospital London
Professor Christopher Weir  Professor of Medical Statistics and Clinical Trials, University of Edinburgh


Our community of reviewers play a vital part in maintaining and improving the quality of the EME Programme projects and outputs. They are sought from a variety of fields, including from those who work in and use NHS services. To demonstrate our gratitude to our reviewers and acknowledge the important work they do for the programme the names of the past year’s reviewers are listed below.

View a list of EME 2018 reviewers.