Efficacy and Mechanism Evaluation (EME)

The Efficacy and Mechanism Evaluation Programme calls on the expertise, knowledge and opinion of a large number of people to ensure that the identification of research areas and funding decisions are chosen in a clear and fair way.

The EME Advisory Committee provides advice to the EME Programme Director on the scientific strategy for the programme.

The EME Funding Committee assesses outline and full proposals and makes funding decisions for the researcher-led workstream, and makes funding recommendations to the Department of Health for the commissioned workstream.

Members of EME Advisory Committees are required to declare any interests which conflict, or may be considered to conflict, with EME business, or may be perceived as influencing decisions made in the course of their work within the EME programme in line with the Conflicts of Interest Policy. All members are asked to complete the Register of Interest form (annually), which is intended to capture long term predictable interests that could be perceived to lead to conflicts of interest. These and other interests are judged on a case by case basis at individual meetings. View the Register of Interests for each EME programme advisory group.

Find out more about becoming a reviewer or current committee member opportunities.

EME Funding Committee 

Interim Director and ChairOrganisation
Professor David Crossman Dean and Head of School of Medicine, University of St Andrews

David Crossman

Professor David Crossman, is Bute Professor of Medicine and the Dean and Head of Faculty of Medicine at University of St. Andrews, Honorary Consultant Cardiologist for NHS Fife Health Board and Chief Scientist for Health, Scotland (from November 2017).

His previous appointments include Head of the School of Medicine at the Norwich Medical School, UEA, Director of the NIHR Cardiovascular Biomedical Research Centre and Professor of Clinical Cardiology at the University of Sheffield.  

He has served on the EME Board (2010-2015) as well as the Wellcome Trust Expert Review Group – Physiology in Health and Disease (2010-2014), British Heart Foundation Chairs and Programme Grants Committee (2004-2009), MRC Physiological Systems and Clinical Sciences Board (2004-2008), as Vice President of Education and Research and Chair of Programme Committee for the British Cardiovascular Society (2006-2008). He was on the cardiovascular panel of RAE 2008 and Unit of assessment panel 1 in REF 2014.

His research interests centre on the inflammatory basis of atherosclerosis and the pathogenesis of myocardial infarction.

Deputy ChairOrganisation
Professor Eric Alton Professor of Gene Therapy and Respiratory Medicine Imperial College London
Dr Simon Bond Senior Statistician from Cambridge Clinical Trials Unit, Addenbrooke’s Hospital Cambridge University Hospitals NHS Foundation Trust
Dr Louise Brown Senior Statistician, MRC Clinical Trials Unit, University College London
Professor Bill Deakin Professor of Psychiatry and Director NPU, Manchester University
Professor Janet Dunn Professor of Clinical Trials & Head of Cancer Trials, University of Warwick
Mr Stephen Edgar Public board member
Professor Carrol Gamble Reader Medical Statistics, University of Liverpool
Professor Paula Ghaneh Professor of Surgery, University of Liverpool, Honorary Consultant Surgeon in Hepatobiliary Surgery, Royal Liverpool University Hospital
Professor Fiona Gilbert Consultant Radiologist, Head of Department of Radiology at the University of Cambridge, Cambridge University Hospitals NHS Foundation Trust
Professor Jonathan Grigg Professor of Paediatric Respiratory and Environmental Medicine, Queen Mary University of London
Professor Ajit Lalvani Director of Tuberculosis Research Centre, National Heart and Lung Institute, Imperial College London
Professor Iain McInnes Professor of Experimental Medicine / Director of Research Institute, University of Glasgow
Professor Michael Nicholson Professor of Transplant Surgery, University of Cambridge
Mr Richard Parnell Public board member
Dr Richard Peck Head of Clinical Pharmacology, Roche Global; Roche Products Ltd. 
Professor John Petrie Professor of Diabetic Medicine, University of Glasgow
Professor Ruth Plummer Professor of Experimental Cancer Medicine, Newcastle University
Professor Rustam Salman Professor of Clinical Neurology & Honorary Consultant Neurologist, University of Edinburgh
Professor Robert Storey Professor and Honorary Consultant in Cardiology, Medical School, University of Sheffield
Professor Frank Sullivan Professor of Family and Community Medicine, University of St Andrews
Professor Steve Thornton Vice Principal (Health) and Executive Dean, Queen Mary University of London
Professor Mark Thursz Professor of Hepatology, Imperial College London and St Mary's Hospital London
Professor Christopher Weir  Professor of Medical Statistics and Clinical Trials, University of Edinburgh



Our community of reviewers play a vital part in maintaining and improving the quality of the EME Programme projects and outputs. They are sought from a variety of fields, including from those who work in and use NHS services. To demonstrate our gratitude to our reviewers and acknowledge the important work they do for the programme the names of the past year’s reviewers are listed below.

View a list of EME 2017 reviewers.