Minutes for the Research for patient Benefit Programme Under-Represented Disciplines and Specialisms Highlight Notice: Methodologists Research Advisory Committee A Stage 2 Meeting

Minutes for the Research for Patient Benefit Programme Under-represented disciplines and specialisms highlight notice: Methodologists Research Advisory Committee A Stage 2 meeting 

Date and Location

Wednesday 17 April 2024 Via Zoom Virtual Meeting

In attendance

Committee Members

Professor Chris Gale (Chair)
Dr David Stephensen (Deputy Chair)
Ms Catherine Arundel
Mrs Wendy Blunden
Professor Gary Collins
Professor David Cromwell
Mr Stephen Edgar
Professor Lyn Ellett
Professor Richard Grieve
Dr Lisa Hinton
Associate-Professor Andrew Judge
Dr Anne Killett
Professor Jos Latour
Professor Marcus Munafo
Ms Stella O'Brien
Professor Judith Rankin
Professor Andy Vail
Professor Bridget Young
Dr Cath Quinn
Professor Steve Pilling

Secretariat

Dr Jennie Hejdenberg, Assistant Director RfPB
Mr Jack Finn (NIHRCC)
Ms Louisa Fox (NIHRCC)
Ms Zuzanna Tajchman (NIHRCC)
Mr Ian Beason (NIHRCC)
Ms Katie Prangle (NIHRCC)
Ms Lavpeet Ranjit (NIHRCC)
Ms Alisha Singh (NIHRCC)

Stage 2 applications considered

NIHR206899: Development and validation of clinical tools for predicting outcome in newly diagnosed epilepsy
Conflicts: Professor Bridget Young, Professor Gary Collins
Final outcome: Conditional support

NIHR206903: OPtimal Timing of Induction of labour to improve Maternal and perinatAL outcomes (OPTIMAL): An individual participant data meta-analysis and qualitative evaluation.
Conflicts: Professor Chris Gale, Professor Gary Collins, Dr Lisa Hinton
Final outcome: Conditional support

NIHR206836: Identifying socioeconomic and ethnic disparities in key health outcomes by hormone replacement therapy use in older women
Conflicts: Professor Marcus Munafo, Professor Gary Collins, Dr Lisa Hinton
Final outcome: Support

NIHR206910: Assessment of neurodevelopmental function in critically ill children enrolled in the Oxy-PICU trial
Conflicts: Professor Jos Latour, Professor Richard Grieve, Dr Lisa Hinton
Final outcome: Conditional support

NIHR206893: Evaluation of Local Anaesthesia in the endovascular repair of ruptured abdominal aortic aneurysms: a Target trial and Economic evaluation (ELATE)
Conflicts: Professor Richard Grieve, Ms Catherine Arundel, Professor David Cromwell, Professor Andrew Judge
Final outcome: Conditional support

NIHR206900: Evaluation of COVID-19 vaccine products and schedules
Conflicts: Professor Marcus Munafo, Professor Gary Collins, Professor David Cromwell, Professor Andrew Judge, Dr Lisa Hinton
Final outcome: Conditional support

NIHR206842: Promoting Accessibility in Clinical Trials (PRACTICALs): Development and pilot testing of an eLearning resource
Conflicts: Professor Marcus Munafo, Professor Chris Gale
Final outcome: Conditional support

NIHR206881: Promoting Accessibility in Clinical Trials (PRACTICALs): Development and pilot testing of an eLearning resource
Conflicts: Dr Anne Killett
Final outcome: Conditional support

NIHR206844: Improving sleep for hospital inpatients: Development and implementation of the ASLEEP toolkit
Conflicts: Professor Jos Latour, Professor Marcus Munafo, Professor Andrew Judge
Final outcome: Rejected

NIHR206897: Target trials for talking and digital enabled therapies to estimate their real-world effectiveness, cost-effectiveness, and inequalities in outcomes using causal inference techniques applied to NHS Talking Therapies real-world data: The Target Therapies quasi-experimental study
Conflicts: Professor Stephen Pilling, Professor Chris Gale, Ms Catherine Arundel, Professor Tom Sanders
Final outcome: Conditional support

NIHR206906: Evaluation of translation and INterpretation serVIces implemented by clinical Trials units (CTUs) to increase recruitment of Ethnic minority groups in pragmatic randomised controlled trials (The INVITE study)
Conflicts: Professor Bridget Young, Professor Marcus Munafo, Professor Andrew Judge
Final outcome: Conditional support

NIHR206924: Can gynaecological cancer surveillance reduce morbidity and mortality in women with Lynch syndrome? A target trial emulation using administrative data
Conflicts: Professor David Cromwell, Professor John Campbell
Final outcome: Reject

NIHR206854: Developing inclusive co-design tools for health-related co-design in partnership with minority ethnic communities.?
Conflicts: None
Final outcome: Support

Outcomes Table

The table below displays the mean score for each application that was assessed in the research assessment committee meeting, and excludes applications which were rejected during the scrutiny and triage processes. The number of applications receiving each mean score are listed. The RfPB fundable range is 4-6, although a score of 4-6 does not guarantee funding. In exceptional circumstances and with approval from the Programme Director, applications may be funded which fall below the fundable range.
In exceptional circumstances, applications which fall below the fundable range may be recommended for funding by the Committee. The Programme Director reviews in detail any applications recommended for funding with a score below 4.

Stage 2