10 Years Of Impact

Researcher looking through slides

Throughout the last ten years, the NIHR has facilitated research that helps to answer key questions for the NHS.


Here are ten examples of the kind of studies the NIHR supports.

Newborn baby

Where is it best to give birth?

For expectant parents, the decision of where they choose to give birth can be a difficult one. Researchers funded by the NIHR compared the safety of births planned to take place in four different settings.


Can football clubs help fans to lose weight?

Although men are more likely to be overweight or obese than women, they are less likely to join weight-loss programmes. The NIHR evaluated an intervention carried out in partnership with Scottish Premier League football clubs - Football Fans in Training.

Child with intraveinous drip

How do you keep Ebola patients hydrated?

Dehydration is a key cause of death in people infected with Ebola. Understanding the advantages and disadvantages of different methods of fluid delivery could help health workers make choices that save lives.

Surgeons operating

How do you stop an aneurysm before it bursts?

It is estimated that around 4 per cent of men aged between 65 and 74 in England have an abdominal aortic aneurysm. The NIHR funded research to compare endovascular repair with the traditional open repair method.

Practicing CPR

Who gives the best CPR? Man or machine

In the UK, there are over 30,000 cardiac arrests a year and the survival rate is poor -  as few as one in ten of those who arrest outside of hospital survive.The NIHR funded research to test the effectiveness of LUCAS-2 - a machine developed to automate and potentially improve CPR.

HPV virus

What part should HPV testing play in cervical screening?

Cervical cancer is the second most common cancer in women under 35 years old: about 2,800 women are diagnosed each year in the UK, leading to about 1,000 deaths. Testing for human papilloma virus (HPV) could add sensitivity to the detection of lesions, but there was a lack of evidence as to the most clinically and cost effective way of combining tests.

Self monitoring of blood sugar levels

Is self monitor of blood sugar levels effective for non-insulin-dependent diabetics?

Diabetes is a major public health problem, with 4 million people in the UK living with the condition and numbers predicted to rise. There had been no evidence that self monitoring of blood sugar levels was actually effective in helping type 2 diabetics who were not using insulin.

Arthritic hands

Are new drugs effective for treating rheumatoid arthritis?

Rheumatoid arthritis is an autoimmune condition that causes pain, swelling and stiffness in the joints. NIHR funded researchers undertook a systematic review of 29 trials on the effectiveness and cost-effectiveness of the drugs and reviewed industry submissions to the National Institute for Health and Clinical Excellence (NICE).

Man with mental health issues

Do new drugs work better than old for schizophrenia?

Pharmacological treatment of schizophrenia began in the early 1950s with the discovery that chlorpromazine had antipsychotic properties. To enable better prescribing decisions, the NIHR aimed to evaluate the relative effectiveness of new drugs, compared to conventional drugs and to clozapine.


Can we use nuts to cure nut allergies?

Peanut allergy is a common disease in developed countries, affecting approximately one in 50 children in the UK. Based on the encouraging results of a small pilot study, NIHR researchers undertook a randomised trial of a new treatment: peanut oral immunotherapy.