General Information Leaflet

Find out more about the Dementias and Neurodegeneration (DeNDRoN) Specialty and how it works.

Dementias and Neurodegeneration Specialty Leaflet




Clinical Studies Groups (CSGs)

Clinical Studies Groups provide strategic oversight, support and monitor development and delivery of specialty research across the UK. The groups aim to ensure high quality delivery of a well-designed and balanced mix of commercial and non-commercial research, and that this is available to all NHS patients. Membership includes clinical, scientific, funding body, patient and carer representatives from around the nation. It provides leadership, facilitated research development and multi-centre collaborations as well as bringing new studies to the clinical environment in an effective and timely manner. CSGs are represented on the NIHR CRN specialty groups, enabling collaboration.

CSGs exists for the following neurodegenerative disorders: 



Our studies

Specialty Profiles for Life Sciences Industry

Find out about what our Dementias and Neurodegeneration specialty can offer the life-sciences industry and why you should place your study in England.

Dementias Sub-Specialty Profile

Neurodegeneration Sub-Specialty Profile



Portfolio Development Groups (PDGs)

Portfolio Development Groups are composed of experienced researchers from diverse disciplines and lay members within the specialty field that promote the development of innovative ideas into funded research. The groups' remits includes identifying research gaps as well as supporting Writing Groups to formulate and prepare grant applications for clinical studies.

PDGs exist for the following neurodegenerative disorders: 

Reaching recruitment targets and beyond

The Dementias and Neurodegeneration (DeNDRoN) Specialty recently assisted the team working on the Parkinson’s Disease (PD) COMM study, a pilot project looking at the cost-effectiveness of different speech and language therapy treatments for people with Parkinson's Disease.

The PD COMM study

A collaborative success: The South Asian Voices Enabling Dementia Care ‘SAVE-D’ study in Manchester

The Dementias and Neurodegeneration (DeNDRoN) speciality supported a study sponsored by University of Manchester titled ‘SAVE-D’ (South Asian Voices Enabling Dementia Care).  This study looked at the challenges that South Asians in Greater Manchester faced, when presented with recognising and addressing memory problems and dementia. The collaboration was a success and, together with DeNDRoN’s support, the team effectively recruited a strong cohort of South Asian individuals from local NHS Trusts and community settings, surpassing the original recruitment target of 180 participants. 

The ‘SAVE-D’ study

Managing Agitation and Raising Quality of Life in Dementia: The MARQUE study

Professor Gill Livingston is a researcher at the Mental Health of Older People Unit, University College London (UCL), and is leading the MARQUE study, a major longitudinal study aimed at improving management of agitation and raising quality of life for people with dementia living in care homes.

Watch Professor Livingston talk about the MARQUE study


The PrOVIDe study - Prevalence of Visual Impairment in Dementia

The risks of developing dementia and visual impairment both increase with age. The PrOVIDe study was designed to better understand the prevalence of visual impairment in people with dementia, and to identify how eye care can be improved for people with dementia. Findings have led to proposals to ensure eye care is recognised as being as important to those with dementia as the general population. The project has also lead to further activity prioritising areas for future research for people with both dementia and visual impairment.

The PrOVIDE study 

Bridging the gap

Assessing a person with dementia in a research study requires a high level of skill and expertise. Having experienced raters available can affect whether the life-sciences industry choose to run a study in the UK. Insight Monthly investigates an innovative programme to increase the number of raters in the Clinical Research Network.

Read about the rater training programme

Helen Robinson: A nurse Prinicpal Investigator

Helen Robinson is an Advanced Nurse Practitioner from Middlesbrough, who became one of the first Nurses to become a Principal Investigator of a research study in her Trust in Tees, Esk and Wear Valleys. We interviewed Helen to find out how and why she got involved in clinical research.

Read Helen's story

Patient and Carer Involvement



Taking part in Parkinson's Disease research: Stephen's story

Stephen Roberts talks about his experience of taking part in Parkinson's Disease research.

Stephen's story

Caring for someone with dementia and taking action on research

Shirley Nurock recalls her experience of caring for someone with dementia and how you can take action on research. 

Shirley's story



Other Resources

Research changed my life: Michelle

Michelle was diagnosed with Parkinson’s in August 2009, which really knocked her for quite a while.  Increasingly, over the last five years, clinical research has helped to rebuild her confidence and given her hope for the future.

Michelle's story 

Why I’m involved in Parkinson's Disease research

Colin Sanders was diagnosed with Parkinson’s in 1999. He’s part of our Research Support Network and is passionate about supporting progress towards a cure. He talks about his involvement in research...

Colin's story

Research Standards: MSNAP guide

This information will guide services participating in the Royal College of Psychiatrists Memory Services National Accreditation Programme (MSNAP) to achieve the two new research standards.

Read the guide

Participating in dementia research poster

Poster to inform patients and carers about taking part in dementia research through Join Dementia Research.

View poster

Engaging global communities in research learning

Enabling understanding of clinical research and its role in improving healthcare is a core objective in the Network. In 2015 the Network’s Workforce, Learning and Organisational Development team partnered with the Digital Learning team at Leeds University to develop an online course; ‘Improving Healthcare through Clinical Research’. The course is free, and available to anyone wanting to learn about clinical research.

Read more

Memory loss leaflet

Memory loss leaflet including a description of dementia, what signs to look for and what to do if you think you or a loved one may have dementia.

Read the leaflet

Maintaining the UK's leading edge

Eight senior clinical academics joined the ranks of the Network in 2015 as Specialty Cluster Leads. Their role? To ensure that the UK remains at the forefront of clinical research so that NHS patients can continue to benefit from leading-edge treatments. Insight magazine learns why and how.

Read more

Research Infrastructure Service Developments to Support Increased Dementia Research in the UK

Following the Prime Minister’s Challenge on Dementia in 2012 the United Kingdom has invested in a number of research infrastructure service improvements, which have enabled the growth of dementia research in the UK.  This poster, originally presented at the Alzheimer's Association International Conference in July 2017, describes developments and their impact.

View the poster