To find out more about current haematology studies you can view a list of studies on the NIHR Clinical Research Network Portfolio Database
The NIHR Clinical Research Network Haematology has been enormously successful in integrating clinical research into NHS clinical service provision, and both developing and delivering a large practice changing portfolio of clinical trials.
As the most integrated clinical research system in the world, the NIHR supports research studies through our funding programmes, training and supporting health researchers, and providing world-class research facilities. We also support dialogue between the life sciences industry and charities to benefit all, and facilitate the involvement of patients and the public to make research more effective.
Last year (2016/2017) the NIHR supported 127 studies on Haematology. The NIHR supported these studies through our funding programmes and our research schools and units. We also support Haematology research through our research infrastructure and our training and career development awards for researchers.
A new gene therapy that has been trialled at the NIHR Imperial Clinical Research Facility could be the first step towards a cure for haemophilia.
People with haemophilia A, the most common type of haemophilia, have a genetic defect that means they do not produce a clotting factor called exogenous factor VIII. In this trial a new therapy that replaces the faulty genes to increase levels of factor VIII was tested in people with severe haemophilia A.
Six of the seven people who received a high dose of the new therapy experienced an increase in factor VIII to normal levels and fewer bleeding events, an effect that was still present a year after the therapy dose.
Research developed by the Picker Institute and commissioned by researchers from the NIHR Collaboration for Leadership in Applied Health Research and Care (CLAHRC) North West London has revealed that information provision and lack of public awareness are some of the biggest issues affecting people with sickle cell disease.
The study highlighted that adults with sickle cell disease had little confidence in the knowledge of emergency care staff, preferring to self manage as much as they could at home and seeing emergency treatment as a very last resort. This comes despite the fact that one in three did not receive enough information about coping with pain and self care.
The infographic that CLAHRC North West London created to share the results of this research - ‘Living with sickle cell disease’ - was winner of the 2017 NIHR Let’s Get Digital competition infographic category.
Currently in the UK women can give blood every 12 weeks and men every 16 weeks. A study jointly funded by the NIHR Blood and Transplant Research Unit in Donor Health and Genomics and NHS Blood and Transplant has found that giving blood more frequently – up to every 8 weeks for men and every 12 weeks for women – has no major side effects and could help to increase blood stocks, according to recent research.
The results showed that over a two-year period, allowing donors to give blood more frequently boosted the supply of blood to the NHS without having a major impact on their health. The team also found that donors with higher initial stores of iron were able to give more blood, suggesting that better screening methods should be sought to detect low haemoglobin in potential donors.
You can find out more about Haematology studies in your area through the UK Clinical Trials Gateway.