NIHR-British Heart Foundation Cardiovascular Partnership

The NIHR-BHF Cardiovascular Partnership brings together experts funded by the NIHR and the British Heart Foundation (BHF) to advance the scientific and research agenda in cardiovascular (heart and circulatory) diseases, ultimately translating scientific discoveries into tangible benefits for people affected by cardiovascular disease. The partnership capitalises on world-leading research expertise and infrastructure as well as cohorts of well-characterised patients. This collective expertise is available for collaborations with industry; especially for the design, development and delivery of early phase exploratory clinical studies.

The NIHR’s early translational infrastructure, which is at the core of the NIHR-BHF Cardiovascular Partnership, has significant expertise and capabilities in cardiovascular science. The NIHR has committed over £41.5 million from 2017- 2022 in cardiovascular research through several of the NIHR Biomedical Research Centres (BRCs), which are also supported by NIHR Clinical Research Facilities (CRFs) and platforms such as genomics, imaging and informatics, including the NIHR Health Informatics Collaborative (HIC).

With a strategy focused on bridging the gap between lab-based science and new treatments for patients, the BHF is the UK’s largest independent funder of research into heart and circulatory diseases. The BHF awarded in 2018 more than £100 million in medical research grants and is committed to reach half a billion pounds by 2020, to support research that will improve the lives of millions of patients.

"The new initiative will allow us to promote collaborative experimental medicine studies, foster new collaborative research programmes and leverage greater support from other external partners, including those in industry."

Professor Sir Nilesh Samani, Medical Director of the British Heart Foundation

Our aim

More than a quarter of all early deaths in the UK are due to heart and circulatory diseases. In addition, there are around 7 million people living with cardiovascular disease in the UK. The aim of NIHR-BHF Cardiovascular Partnership is to catalyse and accelerate the translation of promising research into clinical benefits for patients with heart and circulatory disease.

The NIHR-BHF CV partnership:

identifys shared research priorities and strategic goals that will deliver world-leading research and innovation by NIHR and BHF researchers
provides a collaborative framework for NIHR and BHF Cardiovascular translational research in order to leverage funding and facilitate streamlined delivery of research projects
increases research capacity and capability in cardiovascular research across the NIHR and BHF infrastructure as well as partner organisations.

Benefits

The benefits of the NIHR-BHF CV Partnership are:

faster translation of scientific discoveries into tangible benefits for patients
increased capacity to support early phase clinical research delivery (through development of national cohorts, pulling capability and expertise, developing the next generation of researchers)
increased scope and capacity for high quality of research in an identified area of focus or unmet need
increased operational efficiency for delivery of collaborative, experimental medicine research
multi-centre research enabled through creating a national “research platform” which is underpinned by agreed processes and ways of working
improved interactions with external stakeholders such as industry, patient groups and charities
opportunities to create strategic alignment between the NIHR, BHF, and other key partners for further cardiovascular research in defined areas of need.

Our participating centres

The NIHR-BHF Cardiovascular Partnership is chaired by Professor Keith Channon, who directed the Oxford NIHR Biomedical Research Centre for 10 years and is the BHF Field Marshal Earl Alexander Chair of Cardiovascular Medicine at the University of Oxford.

The Partnership’s operations are coordinated by the NIHR Office for Clinical Research Infrastructure. The participating NIHR Biomedical Research Centres and Clinical Research Facilities host BHF Professors, fellows, BHF Research Centres and/or BHF funded research facilities.

NIHR Biomedical Research Centres

Centres	Academic leads
NIHR Barts Biomedical Research Centre	Professor Panagiotis Deloukas Professor Mark Caulfield
NIHR Bristol Biomedical Research Centre	Professor Gianni Angelini
NIHR Cambridge Biomedical Research Centre	Professor Nick Morrell Professor Ian Wilkinson
NIHR Guy's and St Thomas' Biomedical Research Centre	Professor Ajay Shah Professor Mike Marber
NIHR Imperial Biomedical Research Centre	Professor Sian Harding
NIHR Leicester Biomedical Research Centre	Professor G Andre Ng
NIHR Oxford Biomedical Research Centre	Professor Barbara Casadei Professor Keith Channon
NIHR University College London Hospitals Biomedical Research Centre	Professor Aroon Hingorani

NIHR Clinical Research Facilities

Centres	Academic leads
NIHR Birmingham Clinical Research Facility	Professor Paulus Kirchhof
NIHR Coventry and Warwickshire Clinical Research Facility	Professor Christopher Imray
NIHR Exeter Clinical Research Facility	Professor Angela Shore
NIHR Leeds Clinical Research Facility	Professor Maya H Buch
NIHR Manchester Clinical Research Facility	Professor Chris Miller
NIHR Newcastle Clinical Research Facility	Professor Azfar Zaman
NIHR Royal Brompton & Harefield Clinical Research Facility	Professor Dudley Pennell
NIHR Sheffield Clinical Research Facility	Professor Chris Newman
NIHR Southampton Clinical Research Facility	Professor Nick Curzen

For further information about the NIHR-BHF Cardiovascular Partnership and to find out how to work with us, please contact nocri@nihr.ac.uk

CharitiesHow charities can work with the NIHR, to maximise the value of research to patients and the economy.Cardiovascular DiseaseThe NIHR supports Cardiovascular Disease research through funding, training, support for researchers and by providing world-class facilities.