NIHR Facilities and Services
The NIHR supports a number of initiatives to help researchers, including industry, to access health data, samples and to identify participants for research. We can also help you to analyse and store your research samples at our state-of-the-art facilities.
Access data, samples and analytical support for research
The NIHR BioResource is a panel of over 100,000 highly characterised healthy volunteers and patients with common and rare diseases, who are willing to be approached to participate in research studies investigating the links between genes, the environment, health and disease.
The NIHR BioResource can help you identify and recruit individuals who are tailored to your clinical trial by enabling access to well characterised groups of individuals by genotype and or phenotype. Companies can also receive advice, support and feedback from key opinion leaders, clinicians and academics working in your field of research.
Industry partners can either apply to the NIHR BioResource through:
- a collaboration with a Principal Investigator at one of the UK Biomedical Research Centres
- a commercial agreement with the NIHR BioResource, which would include an initial setup study fee as well as costs associated with volunteers’ enrolment and sample collection/shipment.
A detailed cost for industry-led studies through commercial agreements can be found on the NIHR BioResource website.
For more information please visit the NIHR BioResource website.
UKCRC Tissue Directory
The UK Clinical Research Collaboration (UKCRC) Tissue Directory is a free online resource that catalogues the different types of human sample resources across the UK (biobank, cohort, biorepository, clinical trial etc). It’s the only of its kind that covers all regions, sample types and disease areas.
The UKCRC Tissue Directory has characterized over 180 sample resources, hosting over 400 sample collections, covering 136 diseases and counting. Researchers can search the directory by gender, age, and disease, to either find banked samples or resources that can acquire bespoke collections.
For more information please visit the UKCRC Tissue Directory website.
Clinical Practice Research Datalink (CPRD)
CPRD provides a secure service that enables researchers to obtain high-quality, anonymised primary care records for many different types of health research such as outcomes research, epidemiology and randomised controlled trials. CPRD data and services can be highly tailored to meet your specific research needs.
Data costs are charged at a fixed rate depending upon which data sources are required and the complexity of linkage.
For more information please visit the CPRD website.
Clinical Record Interactive Search (CRIS) and the Dementia CRIS (D-CRIS)
CRIS and D-CRIS provide rapid access to pseudonymised mental health clinical records held in NHS Trust systems. This enables searching of structured and unstructured, free-form clinical data, supplemented by a range of text-mining apps. This allows authorised researchers to swiftly investigate hypotheses and define annonymised patient cohorts. Growing numbers of patients have additionally given pre-consent to be contacted about research projects from information in their records, allowing targeted recruitment for trials and observational studies.
A technical and academic team is available to support CRIS study design and database assembly, and with robust ethics and governance structures already in place, lead times from idea to analysis can be very short.
Access to CRIS is only through collaboration with authorised CRIS researchers.
For more information and to find out about how to collaborate with CRIS researchers visit the CRIS web pages on the Maudsley Biomedical Research Centre website.
The Farr Institute of Health Informatics Research
The Farr Institute delivers high-quality, cutting-edge research using ‘big data’ to advance the health and care of patients and the public. The Institute undertakes blue sky and applied research in health informatics, electronic health data and data science as well as epidemiological studies and clinical programmes and trials.
The Farr Institute provides opportunities for collaboration across its portfolio of expertise and can also undertake research on a contract basis for industry partners in areas where its combined knowledge and resources can add value and generate impact.
For more information please visit the Farr Institute website.
NIHR Health Informatics Collaborative
- The NIHR Health Informatics Collaborative (HIC) provides access to high quality, longitudinal NHS datasets for ethically approved research studies. Access to data is in five clinical areas:
- Acute coronary syndrome
- Critical Care
- Viral hepatitis
- Renal transplantation
Access to data is available through collaboration with academics working at HIC centres. The NIHR HIC requires a number of formal checks prior to approval of data access.
For more information please visit the NIHR HIC website.
Health Data Finder for Research
The Health Data Finder for Research enables you to find information about the UK healthcare data sets that are available for research and directs you to the relevant data custodian experts to request access to these data sets.
For more information please visit the Health Data Finder for Research website.
Sample storage and analytical services
MRC-NIHR National Phenome Centre
The MRC-NIHR National Phenome Centre offers a wide range of services from broad profiling untargeted assays through to targeted assays. These services are offered on a collaborative project basis or as a fee-for-service offering.
For more information visit the MRC-NIHR National Phenome Centre website.
NIHR National Biosample Centre
The NIHR Biosample Centre provides a high quality, high capacity service for biomedical researchers engaged in studies that include the collection, processing, storage and analysis of biological samples from their volunteers and patients. The Biosample Centre operates on a fee for service basis for companies and can provide an end-to-end solution or flexible approach to your sampling needs.
For more information visit the NIHR Biosample Centre website.
Interested in working with these collaborations? Contact the NIHR Office for Clinical Research Infrastrucuture:
- 📧 email@example.com
- ☎ 020 3794 7380
- NIHR Bioresource
- UK Clinical Research Collaboration Tissue Directory
- Clinical Practise Research Datalink
- Clinical Record Interactive Search
- Farr Institute of Health informatics Research
- NIHR Health Informatics Collaborative
- Health Data Finder for Research
- MRC-NIHR National Phenome Centre
- National Biosample Centre
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