NIHR Clinical Research Network Portfolio

At the heart of the Clinical Research Network’s activities is the NIHR Clinical Research Network (NIHR CRN) Portfolio of studies. This consists of high-quality clinical research studies that are eligible for consideration for support from the Clinical Research Network in England.

Research activity (recruitment) data from the NIHR CRN Portfolio is used to inform the allocation of NHS infrastructure for research (including NHS Service Support Costs) and supports the performance management of the Clinical Research Network.

Portfolio help

If you cannot find the answer to your question, please email the Study Support Service Helpdesk.

UK Clinical Research Network Portfolio of studies

The NIHR Clinical Research Network Portfolio is part of the UK Clinical Research Network Portfolio of studies, which comprises the network Portfolios for England, Northern Ireland, Scotland and Wales. These four Portfolios are held on a single information system: the Central Portfolio Management System (CPMS)

Central Portfolio Management System

The Central Portfolio Management System (CPMS) is a cloud-based portfolio management system, which has replaced the UKCRN Portfolio and Industry Application Gateway databases.

By transferring our Portfolio from a database to a management system, we can access the life-cycle of studies in a single system for the first time. This puts us in a stronger position to build greater insight and deliver more effective support, both locally and nationally, for clinical research in the NHS.

Now the Central Portfolio Management System is live, our public Portfolio search function has moved to the UK Clinical Trials Gateway

Benefits of inclusion

The NIHR Clinical Research Network supports researchers and the life sciences industry in developing, setting up and delivering high quality research to time and target in both the NHS and in the wider health and social care environment, across England.

For any study that is eligible or applying for CRN support, whether commercially or non-commercially sponsored, we offer a range of services across the research delivery pathway that will help study feasibility, set up and delivery to time and target, through our Study Support Service. These services includes:

Expert advice

  • We’ll advise you how to make your study work in the NHS environment
  • This may include advice about whether there is capability and capacity to carry out your study in the NHS (feasibility), and aligning your research protocol with NHS priorities
  • We can provide access to patients and the public to give their perspective on your research
  • We’ll help you identify and attribute NHS Service Support for your grant application
  • We’ll also use our specialist knowledge to advise you about NHS research sites, and their strengths and capabilities

Site selection

  • We can use our experience and expertise to identify and engage the right research sites, with the right participants, for your study

NHS Service Support resources

  • We can help arrange access to NHS Service Support once your study is confirmed as eligible for Network support
  • This includes access to NHS pharmacy, radiology and pathology support
  • It also includes access to Network-funded research delivery staff (research nurses, data managers etc) to aid recruitment

Recruiting to time and target

  • We’ll support both you, and your selected sites, to meet you study’s recruitment targets within your timescales
  • We’re happy to offer advice on your recruitment strategy, or suggest alternatives, at any point during the study life-cycle

Active performance monitoring

  • We can help you and your selected sites to performance manage the progress of studies
  • The data that we collect can help to identify and overcome recruitment barriers


ISRCTN registration

Researchers can apply for ISRCTN registration via the Central Portfolio Management System. Non-commercial studies with an interventional component qualify for ISRCTN registration funded by the Department of Health in England.