Alcohol related liver disease
The Alcohol-Related Liver Disease (ARLD) PSP has been set up to identify unanswered questions about alcohol-related liver disease treatments from the point of view of patients, carers and healthcare professionals. The identified questions will be prioritised, resulting in a list of the Top 10 priorities for research.
The objectives of the ARLD PSP are to:
- work with patients and clinicians to identify uncertainties about the effects of alcohol-related liver disease prevention and treatments
- to agree by consensus a prioritised list of those uncertainties for research
- to publicise the results of the PSP and process to the research community
- to take the results to the research commissioning bodies to be considered for funding.
Formed by the James Lind Alliance and funded by the National Institute for Health Research (NIHR) and the British Society of Gastroenterology (BSG), the PSP is being guided by a steering group of patient, carer and clinical group representatives.
What is alcohol-related liver disease?
Alcohol-related liver disease encompasses a range of conditions including fatty liver, fibrosis, cirrhosis, portal hypertension and chronic liver failure, frequently accompanied by sudden episodes of acute or chronic cholestatic liver failure (termed alcoholic hepatitis).
"The number of people with alcohol related liver disease has been increasing over the last few decades: death rates have risen considerably in this time and alcohol is now one of the most common causes of death in the UK. So this is an important area for research. It’s vital that we bring together patients, carers and clinicians to decide jointly what the priorities for research are in this area, and the NIHR is pleased to support the James Lind Alliance in doing so."
Professor Dame Sally C. Davies FRS FMedSci
Chief Medical Officer and Chief Scientific Adviser at the Department of Health
We're grateful to all of the organisations which played a vital role by helping us to promote the survey, and by getting involved in the priority setting.
"Liver Disease is currently the fifth biggest killer disease in the UK and still the most common cause of liver disease is alcohol related - consequently this Priority Setting Partnership is extremely important in developing the most appropriate research to benefit those with and affected by ARLD and support all issues relating to ARLD from prevention and early detection through to best possible treatment and care."
Chief Executive, British Liver Trust
“The gap between the burden of liver disease from alcohol and research efforts in comparison to other causes of liver damage has been stark, and so I really welcome this initiative. In particular it is good to see an emphasis on research that is important to patients”
Professor Sir Ian Gilmore
Chair, Alcohol Health Alliance UK