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The NIHR CRN Non-commercial Portfolio Application service

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In order to improve the process of applying for NIHR CRN support and inclusion on the NIHR CRN Portfolio, we have built a new Non-commercial Portfolio Application service within our Central Portfolio Management System (CPMS).

Our new service allows investigators to apply earlier and receive an eligibility decision sooner to benefit from the full range of support that our study support service offers.

In time, all non-commercial health and care researchers will be able to apply directly to us, regardless of discipline. Through this service, investigators will supply a tailored set of data for review against the Department of Health and Social Care’s Eligibility Criteria. If the study is deemed Eligible, this data will then be used to automatically populate the CPMS study record, with no further requests for information. Data supplied will be visible across the CRN and the devolved administrations ensuring coordinated support across study sites.

The Non-commercial Portfolio Application service was launched in August 2020 and is being rolled out by the CRN in a phased manner, based on study type.

Which studies can use the Non-commercial Portfolio Application service?

The Non-commercial Portfolio Application service is currently available to non-commercial English-led studies applying for ethical and regulatory approval for Clinical Trials of Investigational Medicinal Products (CTIMPs), through the HRA/MHRA’s combined review service (formerly called the Combined Ways of Working).

From 10 November 2021, this service will be extended to studies that do not need, and therefore are not applying for, HRA Approval in the Integrated Research Application System (IRAS).

Updates on which studies can use the Non-commercial Portfolio Application service will be provided here, so please check back regularly.

Information on how all other study types can apply for NIHR CRN support is available on our CRN Portfolio webpage.

How do I apply for NIHR CRN support through the Non-commercial Portfolio Application service?

In order to use the Non-commercial Portfolio Application service, you must first create an account in CPMS. Find out how to create an account and log in to CPMS here.

Before starting your application, it is expected that you will have:

You should submit your application as soon as you have secured full research funding for your study, in line with the Department of Health and Social Care’s (DHSC) Attributing the costs of health and social care research (AcoRD) policy. There is no need to wait until you are ready to apply for ethical and regulatory approvals.

To complete your application you will need to provide a copy of your study protocol and evidence of the research funding you have secured so have these ready before starting your application.

Once we receive your application it will be reviewed against the Department of Health and Social Care’s Eligibility Criteria, and you will be notified of the outcome via email.

Further guidance on how to apply for NIHR Clinical Research Network (CRN) support through the Non-commercial Portfolio Application service is available on NIHR Learn. A supporting video is also available on our Youtube channel.