This site is optimised for modern browsers. For the best experience, please use Google Chrome, Mozilla Firefox, or Microsoft Edge.

HTA Funding Committee Public Minutes 03/04 November 2020

 

Contents

Tuesday 03 November 2020 (Day 1)

Place    

Virtual Meeting via Microsoft Teams

Present members

Professor Lucy Chappell (Chair)
Professor Andrew Farmer (HTA Programme Director)
Dr Natalie Blencowe
Dr Jennifer Bostock (PPI representative)
Dr Kate Brown
Professor Charlotte Coles
Professor Alun Davies
Professor David Ekers
Professor Richard Emsley
Dr Katie Gillies
Dr Chloe Grimmett
Dr Rebecca Harmston (PPI representative)
Ms Jo Haviland
Professor Daniel Hind
Professor William Hollingworth
Professor Sally Hopewell
Dr Susan Jowett
Associate Professor Rebecca Kearney
Mrs Deborah Keatley (PPI representative)
Professor Daniel Lasserson
Dr Jennifer Logue
Professor Alan Montgomery
Professor Gavin Perkins
Professor Thomas Pinkney
Dr Elena Pizzo
Professor Daniel Prieto-Alhambra
Dr Kathryn Radford
Professor Jonathan Rees
Professor Kapil Sayal
Professor James Wason
Professor David Weller
Ms Beth Woods

NETSCC, HTA Secretariat

Dr Jason Horsley (Consultant Advisor, NETSCC)
Ms Steph Garfield-Birkbeck (Head of the HTA Programme Secretariat)
Mrs Karen Williams (Senior Research Manager)
Dr Brogan Ashley (Research Manager)
Miss Constance Temple-Brown (Assistant Research Manager)
Mrs Debbie Carter (Administrator)

Apologies

Professor Sharon Simpson
Dr Elena Pizzo - afternoon

Observers    

Professor Olivia Wu – New CET deputy chair observing November’s Committee meeting.
Professor Marian Knight – New commissioning Chair observing November’s meeting.
Dr Mark Lown – Member of the Secretariat, observing as part of his NIHR training.

Quoracy Information    

Voting members: 32 Quorum = 20
Voting members present on Day 1: 31 (96%)

 

Commissioning Stage 2 Proposals

19/69 Clinical and cost effectiveness of alternative catheter design at preventing catheter-associated urinary tract infection

Chair: Professor Lucy Chappell
Declared a conflict and left the discussion: Dr Chloe Grimmett, Professor Alan Montgomery, Dr Mark Lown, Dr Jennifer Bostock
Declared a conflict and left the call: Professor Andrew Farmer

NIHR131172: Multicentre trial of the clinical and cost effectiveness of a novel urinary catheter design in reducing catheter-associated urinary tract infection compared with the traditional Foley design for adults requiring long-term catheterisation (CADET). (Dr Catherine Murphy, University of Southampton)

Funding Committee recommendation: Programme Oversight Committee to consider fund with changes

 

19/70 Cervical spine immobilisation following blunt trauma

Chair: Professor Andrew Farmer
Declared a conflict and left the discussion: Professor Alun Davies, Professor Rebecca Kearney, Professor Thomas Pinkney
Declared a conflict and left the call: Professor Gavin Perkin, Professor Daniel Lasserson, Professor Daniel Hind

NIHR131430: Cervical Spine Immobilisation Following Blunt Trauma (HTA 19/70) Spinal Immobilisation Study (SIS) (Professor Mark Wilson, Imperial College Healthcare NHS Trust)

Funding Committee recommendation: Decline

Post meeting note (from ID&P): We also need to add a post-meeting note to the FC minutes to advise that following discussion the HTA Programme Director has agreed not to return the brief to POC given that an appropriate team has been identified through the previous open advertisement and in the first instance, we wish to explore with them whether they are able and willing to resubmit a stage 2 application.
Post meeting note: Professor Andrew Farmer (Programme Director) has agreed to change this outcome to Resubmit at Stage 2. 

 

Researcher Led Stage 2 Proposals

 

19/102 HTA Researcher-led call Primary Research

Chair: Professor Lucy Chappell
Declared a conflict and left the discussion: Associate Professor Sally Hopewell, Professor Daniel Prieto-Alhambra, Professor Jonathan Rees, Professor Marian Knight
Declared a conflict and left the call: Professor Andrew Farmer
Arrived at the meeting: Professor Daniel Hind

NIHR130886: Melanoma Margins Trial-II: 1cm v 2cm Wide Surgical Excision Margins for AJCC Stage II Primary Cutaneous Melanoma (MelMarT-II) ClinicalTrials.gov Identifier: NCT03860883 (Professor Marc Moncrieff, Norfolk and Norwich University Hospitals NHS Foundation Trust)

Funding Committee recommendation: Programme Oversight Committee to consider fund with changes

 

19/102 HTA Researcher-led call Primary Research

Chair: Professor Lucy Chappell
Declared a conflict and left the discussion: Professor Alan Montgomery, Professor Thomas Pinkney, Professor William Hollingworth, Professor Marian Knight
Declared a conflict and left the call: Professor Andrew Farmer
Left the meeting: Dr Natalie Blencowe

NIHR131306: Multi-modality local consolidative treatment versus conventional care of advanced lung cancer after first line systemic anti-cancer treatment: a multi-centre randomised controlled trial with an internal pilot. RAdical Management Of Advanced Non-small cell lung cancer (RAMON) (Professor Eric Lim, Royal Brompton & Harefield NHS Foundation Trust)

Funding Committee recommendation: Programme Oversight Committee to consider fund with changes

 

19/102 HTA Researcher-led call Primary Research

Chair: Professor Lucy Chappell
Declared a conflict and left the discussion: Professor Rebecca Kearney
Declared a conflict and left the call: Professor Daniel Lasserson, Professor Gavin Perkins

NIHR131105: Pre-hospitAl Randomised triAl of MEDICation route in out-of-hosital cardiac arrest
(PARAMEDIC3) (Professor Gavin Perkins, University of Warwick)

Funding Committee recommendation: Programme Oversight Committee to consider fund with change

 

19/160 HTA Researcher-led call Primary Research

Chair: Professor Charlotte Coles
Declared a conflict and left the discussion: Dr Katherine Brown, Dr Susan Jowett, Professor Kapil Sayal, Professor Lucy Chappell, Professor Rebecca Kearney, Professor Olivia Wu, Professor Marian Knight, Dr Rebecca Harmston
Declared a conflict and left the call: Professor Andrew Farmer, Professor Alan Montgomery
Arrived at the meeting: Dr Natalie Blencowe

NIHR131837: The clinical and cost-effectiveness of a neonatal sepsis calculator (neoGBS) (Professor Jane Daniels, The University of Nottingham)

Funding Committee recommendation: Decline 

 


19/160 HTA Researcher-led call Primary Research

Chair: Professor Andrew Farmer
Declared a conflict and left the discussion: Dr Susan Jowett, Professor Daniel Hind, Professor Daniel Prieto-Alhambra, Professor James Wason, Professor Jonathan Rees, Professor Lucy Chappell, Professor Rebecca Kearney

NIHR131638: Clinical and cost-effectiveness of individualised exercises and foot orthoses in the treatment of plantar heel pain: a randomised multi-arm multi-stage (MAMS) adaptive trial (TReatments of Exercise AnD Orthotics for plaNtar heel pain (TREADON)) (Dr Edward Roddy, Keele University)

Funding Committee recommendation: Programme Oversight Committee to consider fund with changes

 

19/160 HTA Researcher-led call Primary Research

Chair: Professor Charlotte Coles
Declared a conflict and left the discussion: Dr Kathryn Radford, Dr Susan Jowett, Professor Lucy Chappell, Professor Marian Knight, Dr Mark Lown
Declared a conflict and left the call: Professor Alan Montgomery, Professor Kapil Sayal, Professor Andrew Farmer

NIHR131440: Randomised controlled trial of a new relief inhaler in mild asthma. (Professor Timothy Harrison, The University of Nottingham)

Funding Committee recommendation: Programme Oversight Committee to consider fund with changes

 

19/160 HTA Researcher-led call Primary Research

Chair: Professor Lucy Chappell
Declared a conflict and left the discussion: Associate Professor Sally Hopewell, Professor Daniel Lasserson, Professor Daniel Prieto-Alhambra, Professor Jonathan Rees, Professor Rebecca Kearney, Professor Marian Knight
Declared a conflict and left the call: Professor Gavin Perkins, Dr Jennifer Logue

NIHR131407: Robotic Arthroplasty: a Clinical and cost Effectiveness Randomised controlled trial for Hips (RACER-HIP) (Mr Peter Wall, University of Warwick)

Funding Committee recommendation: Programme Oversight Committee to consider fund with changes

 

19/160 HTA Researcher-led call Primary Research

Chair: Professor Lucy Chappell
Declared a conflict and left the discussion: Dr Jennifer Logue, Professor Daniel Hind

NIHR131692: The clinical and cost-effectiveness of the DESMOND-ID education programme for adults with intellectual disability and Type 2 Diabetes (Dr Laurence Taggart, University of Ulster)

Funding Committee recommendation: Programme Oversight Committee to consider fund with changes

 

19/160 HTA Researcher-led call Primary Research

Chair: Professor Charlotte Coles
Declared a conflict and left the discussion: Professor Daniel Prieto-Alhambra, Professor Gavin Perkins, Professor Lucy Chappell, Professor Marian Knight
Declared a conflict and left the call: Professor Andrew Farmer
Left the meeting: Dr Rebecca Harmston

NIHR131822: T4P (Threshold for Platelets) (Professor Peter Watkinson, University of Oxford)

Funding Committee recommendation: Programme Oversight Committee to consider fund with changes

 

19/160 HTA Researcher-led call Primary Research

Chair: Professor Lucy Chappell
Declared a conflict and left the discussion: None

NIHR131870: A pragmatic multicentre randomised controlled trial to evaluate the effectiveness of MT in improving the quality of life of palliative care patients, and the impact on those close to them. (Professor Sam Porter, Bournemouth University)

Funding Committee recommendation: Decline

 

Researcher Led Stage 1 Proposals 


20/38 HTA Researcher-led call Primary Research

Chair: Professor Lucy Chappell
Declared a conflict and left the discussion: Associate Professor Sally Hopewell, Dr Jennifer Logue, Dr Natalie Blencowe, Professor Daniel Prieto-Alhambra, Professor Gavin Perkins, Professor Jonathan Rees, Professor Rebecca Kearney, Professor Thomas Pinkney, Professor William Hollingworth
Left the meeting: Professor David Ekers

NIHR132955: The clinical and cost-effectiveness of adding a nerve block to spinal or general anaesthesia, in combination with local anaesthetic infiltration, for elective primary total knee replacement. A pragmatic multicentre randomised controlled trial with blinding (Mr Michael Whitehouse, University of Bristol)

Committee recommendation: Decline

 

20/38 HTA Researcher-led call Primary Research

Chair: Professor Andrew Farmer
Declared a conflict and left the discussion: Dr Susan Jowett, Professor Daniel Lasserson, Professor Gavin Perkins, Professor Lucy Chappell, Professor Thomas Pinkney

NIHR132885: DOse of intrathecaL diamORphinE in Surgery - DOLORES trial Multi-arm, multi-stage, multi-centre, open-label, adaptive, sequential dosing, pragmatic randomised trial with an internal pilot, and health economic evaluation (Professor Fang Smith, University of Birmingham)

Committee recommendation: Decline

 

20/38 HTA Researcher-led call Primary Research

Chair: Professor Lucy Chappell
Declared a conflict and left the discussion: Dr Natalie Blencowe, Professor Daniel Lasserson, Professor Rebecca Kearney, Professor William Hollingworth
Declared a conflict and left the call: Professor Gavin Perkins
Left the meeting: Dr Katherine Brown

NIHR131533: Randomised trial of the clinical and cost effectiveness of a supraglottic airway device versus tracheal intubation during in-hospital cardiac arrest (AIRWAYS-3). (Professor Jonathan Benger, UWE Bristol)

Committee recommendation: Shortlist

20/38 HTA Researcher-led call Primary Research

Chair: Professor Lucy Chappell
Declared a conflict and left the discussion: Professor Alan Montgomery
Left the meeting: Dr Jennifer Logue

NIHR132757: Outcomes of Simultaneous versus Staged Resection of synchronous colorectal liver metastases: the SISTAR study (Mr Giuseppe Fusai, Royal Free London NHS Foundation Trust)

Committee recommendation: Decline

 

Wednesday 04 November 2020 (Day 2)

Place    

Virtual Meeting via Microsoft Teams

Present members

Professor Lucy Chappell (Chair)
Professor Andrew Farmer (HTA Programme Director)
Dr Natalie Blencowe
Dr Kate Brown
Professor Charlotte Coles
Professor Alun Davies
Professor Richard Emsley
Dr Katie Gillies
Dr Chloe Grimmett
Professor Daniel Hind
Professor William Hollingworth
Professor Sally Hopewell
Dr Susan Jowett
Associate Professor Rebecca Kearney
Mrs Deborah Keatley (PPI representative)
Dr Jennifer Logue
Professor Alan Montgomery
Professor Gavin Perkins
Professor Thomas Pinkney
Dr Elena Pizzo
Professor Daniel Prieto-Alhambra
Dr Kathryn Radford
Professor Jonathan Rees
Professor Kapil Sayal
Professor James Wason
Professor David Weller
Ms Beth Woods
Dr Jennifer Bostock (PPI representative)

NETSCC, HTA Secretariat

Dr Jason Horsley (Consultant Advisor, NETSCC)
Ms Steph Garfield-Birkbeck (Head of the HTA Programme Secretariat)
Mrs Karen Williams (Senior Research Manager)
Dr Brogan Ashley (Research Manager)
Miss Constance Temple-Brown (Assistant Research Manager)
Mrs Debbie Carter (Administrator)

Apologies

Professor Sharon Simpson
Professor Daniel Lasserson
Professor David Ekers - from 1pm
Ms Jo Haviland
Dr Rebecca Harmston (PPI representative)

Observers    

Professor Olivia Wu – New CET deputy chair observing November’s Committee meeting. 
Professor Marian Knight – New commissioning Chair observing November’s meeting.
Dr Mark Lown – Member of the Secretariat, observing as part of his NIHR training.

Quoracy Information    

Voting members: 32 Quorum = 20
Voting members present on Day 1: 27 (84%)

 

Researcher Led Stage 1 Proposals - Continued

20/38 HTA Researcher-led call Primary Research

Chair: Professor Lucy Chappell
Declared a conflict and left the discussion: Dr Elena Pizzo, Professor Rebecca Kearney, Professor Thomas Pinkney

NIHR132880: FAST MRI UK Screening Trial: a multi-centre randomised controlled trial (RCT), comparing the effectiveness atinterval cancer reduction of abbreviated breast MRI (FAST MRI) and mammography versus mammography alone, for women at population-risk of breast cancer at initial screen (prevalent round) (Dr Lyn Jones, North Bristol NHS Trust)

Committee recommendation: Decline

 

20/38 HTA Researcher-led call Primary Research

Chair: Professor Lucy Chappell
Declared a conflict and left the discussion: Professor David Weller
Left the meeting: Professor Daniel Hind

NIHR132484: Transient Ischaemic Attack and minor Stroke CompArison of imagiNg Study (TIA-SCANS ) (Dr William Whiteley, The University of Edinburgh)

Committee recommendation: Decline

 

20/38 HTA Researcher-led call Primary Research

Chair: Professor Andrew Farmer
Declared a conflict and left the discussion: Professor Lucy Chappell
Arrived at the meeting: Professor Daniel Hind

NIHR131923: Randomised Controlled Trial on the Effectiveness of SSRI Medication to Manage Problematic Sexual Arousal in Adults Convicted of Sexual Offences (Professor Belinda Winder, Nottingham Trent University)

Committee recommendation: Decline

 

20/38 HTA Researcher-led call Primary Research

Chair: Professor Andrew Farmer
Declared a conflict and left the discussion: Dr Elena Pizzo, Dr Susan Jowett, Professor Thomas Pinkney, Professor Marian Knight

NIHR132020: A multi-centre UK Diagnostic Test Accuracy assessment of Urinary Neutrophil Gelatinase Associated Lipocalin (NGAL) and TIMP-2/ IGFBP-7 ratio (Nephrocheck) for the very early diagnosis of Acute Kidney Injury (AKI) following Orthotopic Liver Transplantation (OLT) (Professor Brian Davidson, University College London)

Committee recommendation: Decline

 

20/38 HTA Researcher-led call Primary Research

Chair: Professor Lucy Chappell
Declared a conflict and left the discussion: Dr Kathryn Radford, Professor Alan Montgomery
Declared a conflict and left the call: Professor Kapil Sayal
Left the meeting: Dr Elena Pizzo

NIHR132808: BAY: Behavioural Activation for Young people with depression in specialist child and adolescent mental health services (Dr Bernadka Dubicka, Pennine Care NHS Foundation Trust)

Committee recommendation: Shortlist

 

20/38 HTA Researcher-led call Primary Research

Chair: Professor Lucy Chappell
Declared a conflict and left the discussion: Professor Daniel Hind, Professor Rebecca Kearney
Declared a conflict and left the call: Professor Gavin Perkins
Arrived at the meeting: Dr Elena Pizzo

NIHR132871: Remote multicomponent rehabilitation intervention in survivors of critical illness post hospital discharge: a randomised controlled assessor blind clinical and cost effectiveness trial with internal pilot (Dr Brenda O'Neill, University of Ulster)

Committee recommendation: Shortlist

 

20/38 HTA Researcher-led call Primary Research

Chair: Professor Lucy Chappell
Declared a conflict and left the discussion: None
Left the meeting: Dr Natalie Blencowe

NIHR132737: Evaluating dietary nitrate supplementation as a strategy to enhance exercise capacity in people with chronic obstructive pulmonary disease. The EDEN-COPD trial (Dr Nicholas Hopkinson, Imperial College London)

Committee recommendation: Decline

 

20/38 HTA Researcher-led call Primary Research

Chair: Professor Thomas Pinkney
Declared a conflict and left the discussion: Professor Daniel Hind, Professor Lucy Chappell, Professor Olivia Wu, Professor Marian Knight
Declared a conflict and left the call: Professor Andrew Farmer, Professor Richard Emsley

NIHR132690: Remote psychosocial interventions to prevent avoidable psychiatric hospital admissions in people with serious mental health problems (Professor Anthony Morrison, Greater Manchester Mental Health NHS Foundation Trust)

Committee recommendation: Shortlist

 

20/38 HTA Researcher-led call Primary Research

Chair: Professor Lucy Chappell
Declared a conflict and left the discussion: Professor Thomas Pinkney

NIHR131812: Using web-based behavioural activation to promote physical activity and reduce symptoms in adults living with depression in the community: The eMotion randomised controlled trial. (Professor Colin Greaves, University of Birmingham)

Committee recommendation: Decline

 

20/38 HTA Researcher-led call Primary Research

Chair: Professor Andrew Farmer
Declared a conflict and left the discussion: Professor Lucy Chappell, Professor Richard Emsley
Left the meeting: Professor Daniel Preto-Alhambra 

NIHR132941: EXTRACTion Of Replacement of redundant/malfunctioning leads: EXTRACTOR Study
(Professor Christopher Rinaldi, Guy's and St Thomas' NHS Foundation Trust)

Committee recommendation: Decline

 

20/38 HTA Researcher-led call Primary Research

Chair: Professor Andrew Farmer
Declared a conflict and left the discussion: Dr Kathryn Radford, Dr Susan Jowett, Professor Kapil Sayal, Professor Lucy Chappell, Professor William Hollingworth
Declared a conflict and left the call: Professor Alan Montgomery

NIHR132016: Pharyngeal Electrical stimulation for Acute Stroke dysphagia Trial (PhEAST) (Professor Philip Bath, The University of Nottingham)

Committee recommendation: Shortlist

 

20/38 HTA Researcher-led call Primary Research

Chair: Professor Lucy Chappell
Declared a conflict and left the discussion: Dr Natalie Blencowe, Professor Daniel Hind, Professor Jonathan Rees, Professor Thomas Pinkney, Professor William Hollingworth
Arrived at the meeting: Professor Daniel Prieto-Alhambra, Dr Natalie Blencowe

NIHR132009: A randomised controlled trial to establish the clinical and cost effectiveness of expectant management versus laparoscopic cholecystectomy in patients after successful ERCP and clearance of gallstones from their common bile duct - The Sunflower-ERCP Study (Professor Giles Toogood, Leeds Teaching Hospitals NHS Trust)

Committee recommendation: Shortlist

 

20/38 HTA Researcher-led call Primary Research

Chair: Professor Andrew Farmer
Declared a conflict and left the discussion: Dr Elena Pizzo, Professor James Wason, Professor Lucy Chappell, Professor Richard Emsley
Arrived at the meeting: Professor Thomas Pinkney

NIHR132896: Long term effectiveness and cost-effectiveness of early mental health intervention: Follow up to the Healthy Start, Happy Start study (Professor Paul Ramchandani, University of Cambridge)

Committee recommendation: Shortlist

 

20/38 HTA Researcher-led call Primary Research

Chair: Professor Thomas Pinkney
Declared a conflict and left the discussion: Associate Professor Sally Hopewell, Dr Susan Jowett, Professor Lucy Chappell, Professor Marian Knight
Declared a conflict and left the call: Professor Andrew Farmer

NIHR132851: Tackling statin intolerance with n-of-1 trials (TASINI): cluster randomised controlled trial (Professor Paul Aveyard, University of Oxford)

Committee recommendation: Decline
Post-meeting note: This application had been rejected at the remit and competitiveness stage and as such should not have been seen at funding Committee. No further action will be taken.

 

20/38 HTA Researcher-led call Primary Research

Chair: Professor Lucy Chappell
Declared a conflict and left the discussion: Dr Elena Pizzo, Dr Kathryn Radford, Dr Susan Jowett, Professor Alan Montgomery, Professor Thomas Pinkney, Professor William Hollingworth, Professor Marian Knight, Professor Charlotte Coles
Declared a conflict and left the call: Professor Andrew Farmer

NIHR132685: Adjuvant radiotherapy in patients with high-risk primary cutaneous Squamous Cell Carcinoma AFTER surgery (SCC-AFTER): an open label, multicentre, two-arm phase III randomised trial (Dr Agata Rembielak, The Christie NHS Foundation Trust)

Committee recommendation: Decline

 

20/38 HTA Researcher-led call Primary Research

Chair: Professor Lucy Chappell
Declared a conflict and left the discussion: Associate Professor Sally Hopewell, Professor Jonathan Rees, Professor William Hollingworth, Professor Marian Knight
Declared a conflict and left the call: Professor Andrew Farmer
Left the meeting: Dr Kathryn Radford

NIHR132260: A multicentre RCT of prophylactic laparoscopic cholecystectomy in patients with idiopathic acute pancreatitis (CHIP study)(Dr Srikanth Reddy, Oxford University Hospitals NHS Trust)

Committee recommendation: Decline

 

20/38 HTA Researcher-led call Primary Research

Chair: Professor Lucy Chappell
Declared a conflict and left the discussion: Dr Kathryn Radford, Dr Susan Jowett, Professor Alan Montgomery, Professor Marian Knight, Professor David Weller
Declared a conflict and left the call: Professor Andrew Farmer
Left the meeting: Dr Chloe Grimmett

NIHR132628: Antiplatelet Secondary Prevention International Randomised trial after INtracerebral haemorrhaGe (ASPIRING) (Professor Rustam Salman, The University of Edinburgh)

Committee recommendation: Decline

 

20/38 HTA Researcher-led call Primary Research

Chair: Professor Thomas Pinkney
Declared a conflict and left the discussion: Dr Katherine Brown, Dr Susan Jowett, Professor Daniel Hind, Professor Jonathan Rees, Professor Lucy Chappell, Professor Rebecca Kearney, Professor Marian Knight
Declared a conflict and left the call: Professor Andrew Farmer
Left the meeting: Dr Natalie Blencowe, Professor James Wason

NIHR132845: Statin TherApy for Reducing Events in Elderly patients from the United Kingdom (STAREE-UK): a randomised controlled trial (Professor Richard McManus, University of Oxford)

Committee recommendation: Decline

 

20/38 HTA Researcher-led call Primary Research

Chair: Professor Andrew Farmer
Declared a conflict and left the discussion: Dr Katie Gillies
Arrived at the meeting: Professor James Wason

NIHR132919: Study of technologies for the diagnosis of angle closure glaucoma (ACE) (Professor Augusto Azuara-Blanco, Queen's University Belfast)

Committee recommendation: Decline

 

20/38 HTA Researcher-led call Primary Research

Chair: Professor Andrew Farmer
Declared a conflict and left the discussion: Professor Daniel Prieto-Alhambra, Professor Lucy Chappell
Arrived at the meeting: Professor Daniel Prieto-Alhambra
Declared a conflict and left the call: Professor Alan Montgomery

NIHR132387: Relative vaccine effectiveness of current and emerging influenza vaccines in people aged 65 years and above (Professor Wei Shen Lim, Nottingham University Hospitals NHS Trust)

Committee recommendation: Decline

 

20/38 HTA Researcher-led call Primary Research

Chair: Professor Lucy Chappell
Declared a conflict and left the discussion: Dr Natalie Blencowe, Professor Daniel Hind, Professor Thomas Pinkney, Professor William Hollingworth
Arrived: Dr Natalie Blencowe

NIHR132884: The ASTA trial: A Phase III Randomized, Open Label, Multi-Centre Study of Apixaban Compared to Standard of Care for Thromboembolism Prevention in Patients with Newly Diagnosed Acute Lymphoblastic Leukemia (ALL) Treated with Pegylated L-Asparaginase (Dr Charlotte Bradbury, University of Bristol)

Committee recommendation: Decline

 

20/38 HTA Researcher-led call Primary Research

Chair: Professor Andrew Farmer
Declared a conflict and left the discussion: Dr Elena Pizzo, Professor Lucy Chappell

NIHR132767: Mifepristone for Labour Induction: MOLI (Professor Mark Johnson, Imperial College London)

Committee recommendation: Decline

 

HTA Stage 1 Oral and Dental Health Call


20/40 HTA Oral and dental health

Chair: Professor Andrew Farmer
Declared a conflict and left the discussion: Dr Elena Pizzo, Professor Daniel Hind, Professor James Wason, Professor Lucy Chappell, Professor Olivia Wu
Arrived at the meeting: Dr Jennifer Logue

NIHR132538: A cluster randomised controlled trial of brief alcohol advice delivered in NHS dental practices (Professor Richard Watt, University College London)

Committee recommendation: Decline

 

Stage 1 Researcher-Led Evidence Synthesis Call

20/37 HTA Researcher-led call Evidence Synthesis

Chair: Professor Lucy Chappell
Declared a conflict and left the discussion: None

NIHR132678: Evaluating losartan for stroke prevention (Dr Carmen Coxon, Medicines and Healthcare products Regulatory Agency)

Committee recommendation: Decline