Day 1 - 8 November 2022
Venue
Microsoft Teams
Present Members
- Professor Julia Brown (Chair)
- Professor Mark Peters (Deputy Chair)
- Professor Andrew Farmer (Programme Director)
- Dr Ashley Agus
- Professor Hashim Ahmed
- Dr Ben Carter
- Associate Professor Laura Coates (Committee Member Development Scheme Participant)
- Dr Janet Deane (Committee Member Development Scheme Participant)
- Professor Jugdeep Dhesi
- Professor Jo Dumville
- Professor Nick Francis
- Professor Caroline Free
- Professor Simon Gates
- Mr David Green (Public Committee Member)
- Professor David Harrison
- Thomas Hellyer (Committee Member Development Scheme Participant)
- Professor Kerenza Hood
- Professor Khalida Ismail
- Dr David Keene
- Professor Asma Khalil
- Dr Stephanie MacNeill
- Mr Stuart McIntosh
- Dr Hema Mistry
- Mr Matthew Moore (Public Committee Member)
- Mr Abdullah Pandor
- Professor Craig Ramsay
- Associate Professor Athanasios Saratzis
- Associate Professor Jo Thompson-Coon
- Dr Sara Twaddle
- Dr Dawn-Marie Walker
Secretariat
- Dr Simon Fraser (Consultant Advisor)
- Dr James Morris (Consultant Advisor)
- Cristina Lujan Barroso (Research Manager)
- Kathy Tier (Research Manager)Helen Payne (Senior Research Manager)
- Louisa Saunders (Assistant Research Manager)
Apologies
- Marta Soares
Observers
- Sarah Markham
- Emma Small
- Nefyn Williams
Quoracy Information
- voting members: 28 (Quoracy = 19 = 66%)
- voting members present on day 1: 27 (96%)
Stage 2 Applications
22/1 Health Technology Assessment Programme Researcher-led (Primary Research)
NIHR152069 - A multi-centre randomised controlled trial of standard care versus an accelerated care pathway after cardiac surgery (FARSTER-care). (Dumbor Ngaage)
Chair: Julia Brown
Conflicts: Jo Dumville
Left the meeting: Stephanie MacNeill
Decision: Programme Oversight Committee to consider fund with changes
NIHR152188 - Cooling in Mild Encephalopathy Trial (COMET) (Sudhin Thayyil)
Chair: Julia Brown
Conflicts: Andrew Farmer, Ashley Agus, Hashim Ahmed, Kerenza Hood, David Keene, Mark Peters, Hema Mistry, Dawn-Marie Walker, David Harrison, Thomas Hellyer, Asma Khalil
Left the meeting: Matthew Moore
Decision: Programme Oversight Committee to consider fund with changes
NIHR152157 - OVATION: a randomised comparison of oral and intravenous arsenic trioxide in newly-diagnosed acute promyelocytic leukaemia (Steven Knapper)
Chair: Julia Brown
Conflicts: Kerenza Hood, Hema Mistry, Athanasios Saratzis
Arrived at the meeting: Matthew Moore
Decision: Decline
22/2 Health Technology Assessment Programme Researcher-led (Evidence Synthesis)
NIHR153187 - Treatment options for women with heavy menstrual bleeding: A comprehensive systematic review, network meta-analysis, and health economic assessment. (Bassel Hamameeh Al Wattar)
Chair: Julia Brown
Conflict: Mark Peters
Decision: Programme Oversight Committee to consider fund with changes
22/130 Health Technology Assessment Fast Track
NIHR155567 - CRASH-4 trial (Clinical Randomisation of an Anti-fibrinolytic in Symptomatic mild Head injury in older adults) Intramuscular tranexamic acid for the treatment of symptomatic mild traumatic brain injury in older adults: a randomised, double-blind, placebo-controlled trial (Ian Roberts)
Chair: Julia Brown
Conflict: Caroline Free
Arrived at the meeting: Stephanie MacNeill
Decision: Programme Oversight Committee to consider fund with changes
21/558 Health Technology Assessment Researcher-led (Evidence Synthesis)
NIHR150958 - PROTECT PRegnancy Outcomes using continuous glucose monitoring TEChnology in pregnant women with Type 2 diabetes: A multicentre randomised controlled trial of the clinical and cost-effectiveness of using continuous glucose monitoring in pregnant women with type 2 diabetes (Helen Murphy)
Chair: Mark Peters
Conflicts: Khalida Ismail, Julia Brown, Janet Deane
Decision: Programme Oversight Committee to consider fund with changes
21/592 Health Technology Assessment Broad Brief
NIHR152762 - STARshiP: Screen and Treat with Aspirin to Reduce Pre-eclampsia (Jenny Myers)
Chair: Mark Peters
Conflicts: Hema Mistry, Andrew Farmer, Julia Brown, Khalida Ismail, Athanasios Saratzis, Janet Deane, Asma Khalil
Decision: Programme Oversight Committee to consider fund with changes
22/3 NICE rolling call
NIHR152027 - A randomised controlled trial of regular MRI scans compared to standard care in patients with prostate cancer managed using active surveillance (Hashim Ahmed)
Chair: Julia Brown
Conflicts: Athanasios Saratzis, Mark Peters, Hashim Ahmed, Abdullah Pandor
Left the meeting: Emma Small (observer)
Decision: Programme Oversight Committee to consider fund with changes
NIHR153059 - A novel reliever strategy for children with asthma: CARE-UK: Children’s Anti-Inflammatory Reliever Study (Louise Fleming)
Chair: Julia Brown
Conflicts: Nick Francis, Dawn-Marie Walker, Hashim Ahmed, Craig Ramsay, Abdullah Pandor, Simon Fraser
Left the meeting: Matthew Moore
Decision: Programme Oversight Committee to consider fund with changes
NIHR152262 - Breathing Assistance in CHildren with bronchiolitis (BACHb): a group-sequential two-stratum multicentre open-label randomised clinical trial of respiratory support in infants with acute bronchiolitis (Padmanabhan Ramnarayan)
Chair: Julia Brown
Conflicts: Ashley Agus, Kerenza Hood, David Keene, Mark Peters, Hema Mistry, Thomas Hellyer, Andrew Farmer, Hashim Ahmed, David Harrison, Craig Ramsay, Athanasios Saratzis
Arrived at the meeting: Matthew Moore
Left the meeting: Simon Fraser, Abdullah Pandor
Decision: Programme Oversight Committee to consider fund with changes
22/4 JLA rolling call
NIHR152587 - Identifying the most clinically- and cost-effective exercise prescription for patients with intermittent claudication (MAXIMISE): a component network meta-analysis to answer a James Lind Alliance priority research question. (Sean Pymer)
Chair: Julia Brown
Conflicts: Jo Dumville, Laura Coates, Athanasios Saratzis, Jugdeep Dhesi
Arrived at the meeting: Simon Fraser, Abdullah Pandor
Decision: Programme Oversight Committee to consider fund with changes
NIHR153139 - Randomised Evaluation of rehabilitation after ACute proximal Humerus fracture (the REACH trial) (David Keene)
Chair: Mark Peters
Conflicts: Jo Dumville, Kerenza Hood, Hema Mistry, Janet Deane, David Keene, Andrew Farmer, Stephanie MacNeill, Laura Coates
Decision: Programme Oversight Committee to consider fund with changes
Day 2 - 9 November 2022
Venue
Microsoft Teams
Present Members
- Professor Julia Brown (Chair)
- Professor Mark Peters (Deputy Chair)
- Professor Andrew Farmer (Programme Director)
- Dr Ashley Agus
- Professor Hashim Ahmed
- Dr Ben Carter
- Associate Professor Laura Coates (Committee Member Development Scheme Participant)
- Dr Janet Deane (Committee Member Development Scheme Participant)
- Professor Jugdeep Dhesi
- Professor Jo Dumville
- Professor Nick Francis
- Professor Caroline Free
- Professor Simon Gates
- Mr David Green (Public Committee Member)
- Professor David Harrison
- Thomas Hellyer (Committee Member Development Scheme Participant)
- Professor Kerenza Hood
- Professor Khalida Ismail
- Dr David Keene
- Dr Stephanie MacNeill
- Mr Stuart McIntosh
- Dr Hema Mistry
- Mr Matthew Moore (Public Committee Member)
- Mr Abdullah Pandor
- Professor Craig Ramsay
- Associate Professor Athanasios Saratzis
- Associate Professor Jo Thompson-Coon
- Dr Sara Twaddle
- Dr Dawn-Marie Walker
Secretariat
- Dr James Morris (Consultant Advisor)
- Cristina Lujan Barroso (Research Manager)
- Kathy Tier (Research Manager)
- Vicky Taylor (Assistant Director NETSCC, Applications & Funding)
- Louisa Saunders (Assistant Research Manager)
Apologies
- Asma Khalil
- Marta Soares
- Dr Simon Fraser (Consultant Advisor)
Observers
- Sarah Markham
- Emma Small
Quoracy Information
- voting members: 28 (Quoracy = 19 = 66%)
- voting members present on day 2: 26 (93%)
Stage 1 Applications
22/4 JLA rolling call
NIHR153258 - DEBI: clinical and cost-effectiveness of desogestrel versus the combined oral contraceptive pill for problem bleeding on the etonogestrel implant (Kate Walker)
Chair: Julia Brown
Conflicts: Caroline Free, Hema Mistry, Athanasios Saratzis
Decision: Shortlist
22/12 AI joint call with EME and i4i
NIHR153364 - StratCare Trial 2: Evaluating the clinical and cost-effectiveness of AI-driven stratified care for depression (Jaime Delgadillo)
Chair: Julia Brown
Conflicts: Jo Dumville, Abdullah Pandor
Decision: Shortlist
22/61 Health Technology Assessment Researcher-Led (Primary Research)
NIHR155294 - Inpatient GRAduated Compression stocking use as an adjunct to Extended duration pharmacoprophylaxis for venous thromboembolism prevention – the GRACE multi-centre randomised controlled trial (Alun Davies)
Chair: Julia Brown
Conflicts: Jo Dumville, Craig Ramsay, Khalida Ismail, Athanasios Saratzis, Abdullah Pandor, Jugdeep Dhesi, Hashim Ahmed, David Keene. Andrew Farmer, James Morris
Left the meeting: Matthew Moore
Decision: Shortlist
22/62 Health Technology Assessment Researcher-Led (Evidence Synthesis)
NIHR155310 - Time lapse imaging (TLI) of embryos to improve reproductive outcomes in in-vitro-fertilisation (IVF): individual participant data (IPD) meta-analysis with economic evaluation (Priya Bhide)
Chair: Mark Peters
Conflicts: Simon Gates, Hema Mistry, Athanasios Saratzis
Arrived at the meeting: Matthew Moore
Decision: Decline
NIHR155405 - Non-pharmacological Interventions for Dental Anxiety: a mixed-methods review (Rachel Perry)
Chair: Mark Peters
Declared a conflict and left the meeting: Joanna Thompson-Coon, Andrew Farmer, Stephanie MacNeill, Athanasios Saratzis
Decision: Decline
22/61 Health Technology Assessment Researcher-Led (Primary Research)
NIHR154913 - Compression Hosiery to Avoid the Post Thrombotic Syndrome (COSTA) (Alun Davies)
Chair: Mark Peters
Conflicts: Jo Dumville, Nick Francis, Craig Ramsay, Athanasios Saratzis, Abdullah Pandor, Jugdeep Dhesi, Hashim Ahmed, Janet Deane
Left the meeting: Matthew Moore
Decision: Decline
22/37 Health Technology Assessment Commissioned
Chair: Julia Brown
Conflicts: Jo Dumville, Simon Gates, David Keene, Stephanie MacNeill, Joanna Thompson-Coon, Laura Coates, Hema Mistry, Dawn-Marie Walker, Athanasios Saratzis, Stuart McIntosh, Abdullah Pandor, Ben Carter, Thomas Hellyer
Arrived at the meeting: Matthew Moore
NIHR153652 - Non-pharmacological interventions for Fatigue management in adults with LOng-tErm health conditions (The FLoe study) (Alyson Huntley)
Decision: Decline
NIHR154510 - Clinical and cost-effectiveness of non-drug-based interventions and strategies for the management of fatigue in people with long-term physical and/or mental health conditions: an evidence synthesis. (Emma Healey)
Decision: Decline
NIHR154565 - Effectiveness of non-pharmacological interventions and strategies for the management of fatigue in people with long-term physical and/or mental health conditions (Nicholas Meader)
Decision: Decline
NIHR154628 - Non-pharmacological interventions for fatigue management in adults with long-term physical health conditions (Joseph Chilcot)
Decision: Decline
NIHR154660 - Effectiveness of Interventions For Fatigue in Long term conditions (EIFFEL) (Christopher Burton)
Decision: Shortlist
NIHR155181 - Evaluating the psychometric properties of patient-reported outcome measures of fatigue in people with long-term physical and mental health conditions: An evidence synthesis using COSMIN methodology (Thomas Wilkinson)
Decision: Decline
NIHR155264 - Non-pharmacological interventions for fatigue management in adults with long-term health conditions: evidence syntheses (Kimberley Smith)
Decision: Decline
NIHR155873 - Evidence synthesis of mixed studies of behavioural interventions for managing fatigue in free-living adults with long term physical and mental health conditions. (Leisle Ezekiel)
Decision: Decline
22/61 Health Technology Assessment Researcher-Led (Primary Research)
NIHR155292 - RIVaroxaban in Abdominal aortic aneurysms for the Long term prevention of major adverse cardiovascular events: the RIVAL randomised-controlled trial (Alun Davies)
Chair: Andrew Farmer
Conflicts: Jo Dumville, Mark Peters, Athanasios Saratzis, Jugdeep Dhesi, Hashim Ahmed, Julia Brown
Arrived at meeting: Khalida Ismail
Left the meeting: Emma Small (observer)
Decision: Decline
22/64 JLA call
NIHR154252 - Randomised trial examining clinical and cost effectiveness of three antithrombotic regimens following endovascular lower limb revascularisation for chronic limb threatening ischaemia: CLARITY (CLopodogrel, Aspirin and RIvaroxaban after revascularIsation with angioplasTY) (Christopher Twine)
Chair: Mark Peters
Conflicts: Jo Dumville, Nick Francis, Athanasios Saratzis, Hashim Ahmed, Kerenza Hood, Julia Brown
Decision: Shortlist
NIHR155220 - A double-blind randomised placebo-controlled trial to assess the effectiveness and cost-effectiveness of oral Corticosteroids in patients witH fibrOtic hypeRsensitivity pneUmonitiS (CHORUS) (Michael Gibbons)
Chair: Julia Brown
Conflicts: Ashley Agus, Joanna Thompson-Coon, David Keene, Thomas Hellyer
Arrived at meeting: Athanasios Saratzis
Decision: Shortlist