Minutes for the Research for Patient Benefit (RfPB) programme London Regional Advisory Committee meeting to discuss Stage 2 applications to competition 44 and Stage 1 applications to competition 45.
Date and Location
Thursday 23 September 2021 Virtual Meeting
In attendance
Committee members
Professor Brian Davidson (Chair)
Dr Elizabeth Bancroft
Miss Eva Broeckelmann
Dr Catey Bunce
Mr Martin Carroll
Dr Julia Chisholm
Professor Francesco D'Aiuto
Ms Mikaela Davies
Dr Anna De Simoni
Dr Martina Di Simplicio
Dr Johnny Downs
Dr Chris Gale
Professor Hemant Kocher
Dr Philip Kinghorn
Dr Dev Malhotra
Dr Aidan O’Keeffe
Dr Katie Sheehan
Professor Christina Victor
Dr Charlotte Warren-Gash
Secretariat
Ms Tembi Huna (NIHR CCF)
Mr Ben Morgan (NIHR CCF)
Dr Jennie Hejdenberg (NIHR CCF)
Ms Nikolett Jozsika (NIHR CCF)
Ms Harkerat Jandu (NIHR CCF)
Professor Sue Ziebland (Programme Director)
Observers
Ms Naina Patel - (RDS YH)
Ms Thando Katangwe-Chigamba - (RDS EE)
Apologies
Apologies were received from Dr Johnny Downs, Professor Francesco D'Aiuto, Professor Hemant Kocher.
Competition 44 stage 2 applications considered
1.1 NIHR203152: A feasibility study COmparing UroLift Standard Transurethral Resection of Prostate Ahead of Radiotherapy in men with urinary symptoms secondary to prostate enlargement (CO-STAR)
Conflicts: Dr Elizabeth Bancroft and Dr Catey Bunce left the room
Final outcome: Conditional support
1.2 NIHR203123: Adapting a smartphone-based rehabilitation programme for older adults living with and beyond cancer: a development study using Intervention Mapping
Conflicts: Professor Brian Davidson, left the room. Dr Christopher Gale chaired the discussion.
Final outcome: Conditional support
1.3 NIHR203170: Development and feasibility testing of an intervention to prevent potentially harmful skincare practices during infancy
Conflicts: Dr Catey Bunce, Dr Martina Di Simplicio and Dr Christopher Gale left the room
Final outcome: Conditional support
1.4 NIHR203151: Exploring the feasibility of using Nasal High Flow (NHF) as a treatment for disabling and intractable breathlessness in patients with Chronic Respiratory Disease (CRD)
Conflicts: None
Final outcome: Reject
1.5 NIHR203158: Investigating the effects of yoga for adults with cystic fibrosis (YOGA-CF)
Conflicts: None
Final outcome: Reject
Competition 45 stage 1 applications considered
2.1 NIHR203524: Being kind to ourselves: A feasibility randomised controlled trial of Compassion Focused therapy (CFT) to improve depression and anxiety in Dementia
Conflicts: Dr Philip Kinghorn and Professor Christina Victor left the room
Outcome: Invite to Stage 2
2.2 NIHR203552: Development of an Artificial Intelligence (AI) method for measuring eczema severity in all skin tones
Conflicts: None
Outcome: Invite to Stage 2
2.3 NIHR203610: A feasibility multicentre randomised controlled trial comparing Wide-awake Local Anaesthesia No Tourniquet (WALANT) versus General and Regional Anaesthesia for Flexor Tendon Repair (WAFER Trial)
Conflicts: Professor Brian Davidson and Dr Anna De Simoni left the room. Dr Christopher Gale chaired.
Outcome: Invite to Stage 2
2.4 NIHR203545: A MULTI-centre feasibility study to assess the use of 99m Tc-SestaMIBI SPECT/CT in the diagnosis of kidney tumours (MULTI-MIBI study).
Conflicts: Professor Brian Davidson and Dr Anna De Simoni remained out of the room. Dr Christopher Gale chaired.
Outcome: Invite to Stage 2
2.5 NIHR203546: iCARE: Development of an intervention to increase enjoyable aCtivities and promote well-being for people living with Advanced dementia and their caREers
Conflicts: None. Dr Christopher Gale chaired.
Outcome: Reject
2.6 NIHR203601: Developing a minimal medication treatment choice for people with psychotic conditions
Conflicts: None. Dr Chritopher Gale chaired.
Outcome: Invite to Stage 2
2.7 NIHR203526: Co-producing Recommendations To Support Early Diagnosis Of Colorectal Cancer In Community Pharmacy
Conflicts: None. Dr Christopher Gale chaired.
Outcome: Invite to Stage 2
2.8 NIHR203528: Face-to-face And Telehealth Equivalence of assessments in Aphasia (FATE-A)
Conflicts: None. Dr Christopher Gale chaired.
Outcome: Reject
2.9 NIHR203604: Eczema and Dermatitis – Implementing The Combined ApproacH (END-ITCH)
Conflicts: Dr Anna De Simoni left the room. Dr Christopher Gale chaired.
Outcome: Invite to Stage 2
2.10 NIHR203589: Co-designing a toolkit to support people with chronic breathlessness experiencing social isolation and loneliness
Conflicts: Dr Catey Bunce and Dr Katie Sheehan left the room. Dr Anna De Simoni remained out of the room. Dr Christopher Gale chaired.
Outcome: Reject
2.11 NIHR203523: Understanding health and eHealth literacy, digital usage and attitudes to digital health tools in the older adult undergoing surgery; an observational study.
Conflicts: Dr Katie Sheehan remained out of the room. Dr Christopher Gale chaired.
Outcome: Reject
2.12 NIHR203529: Effectiveness of suicide prevention interventions in people at risk of suicide: A systematic review of randomised controlled trials and network meta-analysis
Conflicts: Professor Brian Davidson and Dr Martina Di Simplicio left the room. Dr Christopher Gale chaired.
Outcome: Reject
2.13 NIHR203566: Evaluating a brief novel treatment for COVID-related Post-Traumatic Stress Disorder (PTSD) in the Health and Social Care workforce: a pre-RCT preparatory study
Conflicts: Dr Elizabeth Bancroft left the room. Dr Christopher Gale chaired.
Outcome: Invite to Stage 2
2.14 NIHR203602: Reducing PERSISTENT PHYSICAL SYMPTOMS ATTENDANCE in EMERGENCY DEPARTMENT - PPSA-ED
Conflicts: None. Dr Christopher Gale chaired.
Outcome: Invite to Stage 2
Outcomes tables
The tables below display the mean score for each application that was assessed in the regional assessment committee meeting, and excludes applications which were rejected during the scrutiny and triage processes. The number of applications receiving each mean score are listed. The RfPB fundable range is 6-10, although a score of 6-10 does not guarantee funding or an invitation to Stage 2. In exceptional circumstances and with approval from the Programme Director, applications may be invited/funded which fall below the fundable range.
In exceptional circumstances, applications which fall below the fundable range may be invited to Stage 2 or recommended for funding by the Committee. The Programme Director reviews in detail any applications recommended for funding with a score below 7.
Competition 45 stage 1
| Score | Range | Number of applications |
|---|---|---|
| 9.0 - 10.0 | Invited | 0 |
| 8.0 - 8.9 | Invited | 0 |
| 7.0 - 7.9 | Invited | 3 |
| 6.0 - 6.9 | Invited | 5 |
| 5.0 - 5.9 | Invited | 1 |
| 5.0 - 5.9 | Rejected | 3 |
| 4.0 - 4.9 | Rejected | 1 |
| 3.0 - 3.9 | Rejected | 1 |
| 2.0 - 2.9 | Rejected | 0 |
| 1.0 - 1.9 | Rejected | 0 |
Competition 44 stage 2
| Score | Range | Number of applications |
|---|---|---|
| 9.0 - 10.0 | Fundable | 0 |
| 8.0 - 8.9 | Fundable | 1 |
| 7.0 - 7.9 | Fundable | 0 |
| 6.0 - 6.9 | Fundable | 2 |
| 5.0 - 5.9 | Rejected | 1 |
| 4.0 - 4.9 | Rejected | 1 |
| 3.0 - 3.9 | Rejected | 0 |
| 2.0 - 2.9 | Rejected | 0 |
| 1.0 - 1.9 | Rejected | 0 |