Research for Patient Benefit Programme- London Competition 51 Stage 1 Competition 50 Stage 2 Minutes

Minutes for the Research for Patient Benefit (RfPB) programme London Regional Advisory Committee meeting to discuss Stage 2 applications to Competition 50 and Stage 1 applications to Competition 51.

Date and Location

Wednesday 27 September 2023 Virtual Meeting

In attendance

Committee members

Professor Chris Gale (Chair)
Dr Jacqueline Birks
Dr Thomas Booth
Miss Eva Broeckelmann
Professor Kate Brown
Dr Julia Chisholm
Professor Francesco D'Aiuto
Ms Mikaela Davies
Dr Anna De Simoni
Dr Johnny Downs
Mr Thomas Hamborg
Dr Philip Kinghorn
Dr Rachel Philips
Dr Mariana Pinto Da Costa
Dr Katie Sheehan
Dr Cristina Fernandez Turienzo
Professor Charlotte Warren-Gash
Mary Harvey 
Ms Eva Driskell 

Secretariat

Mr Richard Foulsham (NIHRCC)
Dr Kasia Kuleszewicz (NIHRCC)
Ms Lavpreet Randit (NIHRCC)
Mr Conor Ford (NIHRCC)

Competition 50 Stage 2 applications considered

NIHR206229: A feasibility randomised controlled trial assessing Acellular Dermal Matrix (ADM) use in Implant based breast Reconstruction Evaluation (ADMIRE Trial).
Conflicts: None

Final outcome: Rejected

NIHR206166: The development and validation of a risk score : LUng Cancer Improved Decisions (LUCID)
Conflicts: None

Final outcome: Conditional support

NIHR206179: Co-designing Optimal Strategies for the Prevention, Detection and Management of Insulin Mediated Lipohypertrophy in People with Type 1 Diabetes.
Conflicts: None

Final outcome: Conditional support

NIHR206208: A randomised multi-centre trial assessing the duration of anti-coagulation treatment for LV thrombus of ischaemic aetiology (DURATION-LVT Study)
Conflicts: None

Final outcome: Rejected

NIHR206174: Parental experience of novel post-mortem imaging following miscarriage: an exploratory study
Conflicts: Professor Katherine Brown

Final outcome: Conditional support

Competition 51 Stage 1 applications considered

NIHR206680: To validate remote digital image-based surgical wound monitoring as a method to diagnose surgical site infections (DIAMOND)
Conflicts: None

Outcome: Invite to Stage 2

NIHR206694: Exploring the impact of endocrine therapy brand switching in patients with breast cancer (SWITCH)
Conflicts: None

Outcome: Invite to Stage 2

NIHR206718: PlatEleT-rich plasma and Autologous lipotransfer to treat vulvar fibrosis in Lichen Sclerosus – the PETALS multicentre randomised controlled feasibility trial
Conflicts: None

Outcome: Invite to Stage 2

NIHR206589: Medication brand changes in hormone therapy for breast cancer. A community pharmacy intervention development to improve patients’ adherence and quality of life. ENABLE
Conflicts: Miss Eva Broeckelmann

Outcome: Invite to Stage 2

NIHR206676: Tackling the Repercussions of UK-based Stigma towards Tuberculosis (TRUST): a participatory study to co-design a stigma reduction intervention
Conflicts: None

Outcome: Invite to Stage 2

NIHR206696: Developing and refining a virtual reality intervention that will help to manage pain for people living with advanced cancer
Conflicts: None

Outcome: Invite to Stage 2

NIHR206672: A feasibility study to evaluate the impact and acceptability of diagnostics-driven antifungal management and stewardship in paediatric haemato-oncology and bone marrow transplant patients - The DIDAcTIC (Diagnostic Driven Antifungal STewardship In Children) study.
Conflicts: Dr Julia Chisholm

Outcome: Invite to Stage 2

NIHR206684: Developing a perinatal mental health peer support intervention to address the needs of women with experience of intimate partner violence (IPV): a qualitative study
Conflicts: None

Outcome: Invite to Stage 2

NIHR206711: The TRAIN Trial - an evaluation of the management of TRaumatic nAIlbed iNjuries
Conflicts: Dr Chris Gale and Mr Thomas Hamborg

Outcome: Reject

NIHR206664: Stress Echocardiography with Carotid Ultrasound vs Routine CT Coronary Angiography in suspected Chronic Coronary Syndrome for the detection of obstructive coronary disease and prevention of adverse outcomes - A randomised controlled trial.
Conflicts: None

Outcome: Reject

NIHR206743: GANIMEDE: Generative Artificial Intelligence Applied to NHS Cardiology Investigations for Patient Empowerment
Conflicts: Dr Chris Gale

Outcome: Reject

Outcomes Table

The tables below display the mean scores for each application that was assessed in the regional assessment committee meeting. They exclude applications that were rejected during the scrutiny and triage processes. 

Stage 2

Stage 1