Minutes for the Research for Patient Benefit (RfPB) programme South East & Central Regional Advisory Committee meeting to discuss Stage 2 applications to Competition 47 and Stage 1 applications to Competition 48.
Date and Location
Wednesday 28 September 2022 Hybrid Meeting
In attendance
Committee members
Professor Carrie Llewellyn (Chair)
Professor Elizabeth Barley
Mrs Wendy Blunden
Dr Nadia Brookes
Professor Michael Calnan (virtual)
Professor Daniel Freeman
Dr Margaret Glogowska
Ms Rosemary Greenwood (virtual)
Professor Mark Hayward (virtual)
Dr Christina Jones
Miss Alison Provins
Profesor Najib M Rahman (virtual)
Mrs Ketta Shimmin
Dr Beverly Shirkey (virtual)
Dr David Stephensen
Dr Joanna Thorn
Associate Professor Malcolm West
Dr Peter Worsley (virtual)
Secretariat
Dr Elisabeth Kugelberg (NIHR)
Dr Kasia Kuleszewicz (NIHR)
Ms Genis Fernandes (NIHR)
Ms Emily Griffiths (NIHR)
Dr Ianina Conte (NIHR, virtual)
Mr Ian Beason (NIHR, virtual)
Professor Marian Knight (Programme Director)
Competition 47 Stage 2 applications considered
NIHR204302: What outcomes are important to patients with osteoarthritis? Development of a core outcome set
Conflicts: Professor Najib Rahman, Mrs Rosemary Greenwood, Dr Joanna Thorn
Dr Beverly Shirkey left the room
Final outcome: Rejected
NIHR204343: Co-production of a web-based application to reduce malnutrition in people diagnosed with colorectal cancer by providing tailored support for nutrition self-management.
Conflicts: Associate Professor Malcolm West left the room
Final outcome: Rejected
NIHR204314: Developing an Inflammatory Bowel Disease Specific Frailty Assessment Tool
Conflicts: Dr Margaret Glogowska left the room
Final outcome: Rejected
NIHR205011: Progressive resistance exercises versus usual care for improving pain and function after distal radius fracture in adults aged 50 years or over: the WISE randomised superiority trial
Conflicts: Dr Joanna Thorn, Professor Daniel Freeman, Dr Beverly Shirkey left the room
Final outcome: Conditional support
NIHR204349: Fan Feasibility Randomised Controlled Trial (RCT) for people living with COPD and high SABA intake (Fan FIRST)
Conflicts: None
Final outcome: Conditional support
Competition 48 Stage 1 applications considered
NIHR204989: External validation of prediction models using trends in routine blood tests for early detection of colorectal cancer
Conflicts: Dr Margaret Glogowska, Miss Alison Provins, Professor Najib Rahman
Dr Beverly Shirkey left the room
Outcome: Rejected
NIHR204885: Facilitating safe transition to home for preterm infants - a retrospective observational study
Conflicts: None
Outcome: Invited to Stage 2
NIHR204936: iPREGCARE: impact of Personalised Genetic Counselling for couples with a child affected by a disorder caused by a de novo mutation
Conflicts: Dr Joanna Thorn, Dr Margaret Glogowska left the room
Outcome: Invited to Stage 2
NIHR204946: A qualitative investigation of the experience of living with Mast Cell Activation Syndrome (MCAS) and development of an internet-based resource (healthtalk.org) for patients and professionals.
Conflicts: Dr Margaret Glogowska remained out of the room
Outcome: Rejected
NIHR204947: Is Peanut oral immunotherapy more effective in toddlers compared to older children? Recruiting children aged 2-3 years to the NATASHA study, a randomised controlled trial evaluating oral immunotherapy for peanut allergy in children and young people
Conflicts: Dr Christina Jones, Dr Peter Worsley left the room
Outcome: Invited to Stage 2
NIHR204893: Using the Hegenberger retractor for postpartum perineal suturing: is it acceptable to women and health professionals? The HERet study.
Conflicts: None
Outcome: Rejected
NIHR204887: Understanding the role of social prescribing link workers to make recommendations for implementation for people living with physical and mental health long term conditions: a qualitative study
Conflicts: Dr Margaret Glogowska, Associate Professor Malcolm West, Dr Peter Worsley, Dr Joanna Thorn left the room
Outcome: Rejected
NIHR204909: Evaluating a Social Network Intervention which has been co-adapted to Support Recovery for People living with Severe Mental Illness
Conflicts: Professor Elizabeth Barley left the room, Dr Peter Worsley remained out of the room
Note: This application was submitted from within the North West region.
Outcome: Rejected
NIHR204931: Understanding the variation of modern endoscopic ultrasound use in patients with oesophageal cancer (VALUE): a multi-methods study
Conflicts: Associate Professor Malcolm West left the room, Dr Peter Worsley remained out of the room
Outcome: Invited to Stage 2
NIHR204943: Improving detection and management of glucocorticoid-induced diabetes
Conflicts: Professor Najib Rahman
Outcome: Invited to Stage 2
NIHR204982: FRACT-AI: Evaluating the Impact of Artificial Intelligence-Enhanced Image Analysis on the Diagnostic Accuracy of Frontline Clinicians in the Detection of Fractures on Plain X-Ray
Conflicts: Dr Margaret Glogowska left the room, Professor Najib Rahman remained out of the room
Outcome: Invited to Stage 2
Outcomes Table
The tables below display the mean score for each application that was assessed in the regional assessment committee meeting, and excludes applications which were rejected during the scrutiny and triage processes. The number of applications receiving each mean score are listed. The RfPB fundable range is 6-10, although a score of 6-10 does not guarantee funding or an invitation to Stage 2. In exceptional circumstances and with approval from the Programme Director, applications may be invited/funded which fall below the fundable range.
In exceptional circumstances, applications which fall below the fundable range may be invited to Stage 2 or recommended for funding by the Committee. The Programme Director reviews in detail any applications recommended for funding with a score below 7.
Stage 2
| Score | Range | Number of applications |
|---|---|---|
| 9.0 - 10.0 | Fundable | 0 |
| 8.0 - 8.9 | Fundable | 0 |
| 7.0 - 7.9 | Fundable | 2 |
| 6.0 - 6.9 | Fundable | 0 |
| 5.0 - 5.9 | Rejected | 1 |
| 4.0 - 4.9 | Rejected | 1 |
| 3.0 - 3.9 | Rejected | 0 |
| 2.0 - 2.9 | Rejected | 0 |
| 1.0 - 1.9 | Rejected | 0 |
Stage 1
| Score | Range | Number of applications |
|---|---|---|
| 9.0 - 10.0 | Invited | 0 |
| 8.0 - 8.9 | Invited | 0 |
| 7.0 - 7.9 | Invited | 3 |
| 6.0 - 6.9 | Invited | 3 |
| 5.0 - 5.9 | Rejected | 3 |
| 4.0 - 4.9 | Rejected | 2 |
| 3.0 - 3.9 | Rejected | 0 |
| 2.0 - 2.9 | Rejected | 0 |
| 1.0 - 1.9 | Rejected | 0 |