Minutes for the Research for Patient Benefit (RfPB) programme South West Regional Advisory Committee meeting to discuss Stage 2 applications to Competition 49 and Stage 1 applications to Competition 50.
Date and Location
Friday 26 May 2023 Virtual Meeting
In attendance
Committee members
Professor Robert Hinchliffe (Chair)
Dr Sarah Bailey
Dr Ashwin Dhanda
Dr Elsa Marques
Dr Antonieta Medina-Lara
Dr Siobhan O’Dwyer
Mrs Carol-Anne Partridge
Miss Shelley Potter
Mr Philip Ruthen
Dr Jenny Scott
Mrs Hilary Shergold
Dr Sarah Voss
Dr Julia Wade
Secretariat
Mr Simon Goodwin (NIHRCC)
Dr Ianina Conte (NIHRCC)
Ms Sadika Aktar (NIHRCC)
Ms Sophie Tattersall (NIHRCC)
Competition 49 Stage 2 applications considered
NIHR205332: KETO-START: co-design of a programme to support initiation, adherence and continuation of ketogenic diet therapy for children and young people with epilepsy and their parents/carers
Conflicts: None
Final outcome: Conditional Support
NIHR205326: Improving Access to Psychological Therapies for Children with Distressing Sensory Experiences: The Feasibility and Acceptability of the ChUSE Trial, a Novel Child-focused and Parent Intervention
Conflicts: None
Final outcome: Conditional Support
NIHR206250: Randomised controlled feasibility trial of once weekly Semaglutide and a weight management programme to promote weight loss in women living with obesity from an ethnically diverse deprived inner city population seeking removal of long acting reversible contraception in order to plan pregnancy
Conflicts: None
Final outcome: Reject
NIHR205307: DEveloping Pain Management STrategies in Mental Health Services (DEPTH)
Conflicts: None
Final outcome: Reject
Competition 50 Stage 1 applications considered
NIHR206198: Preventing kidney injury using carbon dioxide in patients with Peripheral Arterial Disease (PAD) and Chronic Kidney Disease (CKD) having arterial intervention: the KID trial.
Conflicts: Professor Robert Hinchliffe
Outcome: Invite to Stage 2
NIHR206215: Development and formative evaluation of an internet-based resource (healthtalk.org) for patients and professionals based on a qualitative investigation of the experience of living with Mast Cell Activation Syndrome (MCAS)
Conflicts: None
Outcome: Invite to Stage 2
NIHR206192: ‘Love my Lungs’: Feasibility study to test delivery and preliminary evaluation of a smokefree home intervention for families of babies admitted to neonatal intensive care
Conflicts: None
Outcome: Invite to Stage 2
NIHR206187: Trial of novel airway pack (CAVI-T) vs usual care (Rapid Rhino) in the treatment of epistaxis – a feasibility study
Conflicts: Mr Philip Ruthen
Outcome: Reject
NIHR206227: Using surface neuromuscular electrical stimulation for lower limb weakness early afterstroke: A randomised controlled feasibility study
Conflicts: Dr Elsa Marques
Outcome: Invite to Stage 2
NIHR206135: Development of a core outcome set for revision hip and knee replacement
Conflicts: Professor Robert Hinchliffe, Dr Julia Wade and Dr Elsa Marques
Outcome: Reject
NIHR206193: Aspirin plus Clopidogrel or Ticagrelor For Acute ischaemic Stroke and TIA (ACT-FAST): a prospective, randomised, open-label, blinded end-point, feasibility trial
Conflicts: None
Outcome: Reject
NIHR206169: STOpping PpI Therapy in inactive IBD Study (STOP-IT): A feasibility study
Conflicts: None
Outcome: Reject
NIHR206109: Investigating the acceptability and accuracy of cervical screening and self-sampling in postnatal women at the 6-week postnatal check
Conflicts: Professor Robert Hinchliffe
Outcome: Reject
NIHR206224: Evaluating the effects of strength training on frailty during treatment for relapsed/refractory multiple myeloma: a feasibility study
Conflicts: None
Outcome: Reject
NIHR206246: Mindfulness-Based Cognitive Therapy (MBCT) for Depressed Treatment Non-Responders: Individual Patient Data Meta-Analysis and Evaluation of Service Data
Conflicts: Dr Antonieta Medina-Lara and Dr Rebecca Abbott
Outcome: Reject
NIHR206223: Exploring and understanding the assessment of non-cognitive symptoms (NCS) in people living with dementia.
Conflicts: None
Outcome: Reject
Outcomes Table
The tables below display the mean score for each application that was assessed in the regional assessment committee meeting, and excludes applications which were rejected during the scrutiny and triage processes. The number of applications receiving each mean score are listed. The RfPB fundable range is 6-10, although a score of 6-10 does not guarantee funding or an invitation to Stage 2. In exceptional circumstances and with approval from the Programme Director, applications may be invited/funded which fall below the fundable range.
In exceptional circumstances, applications which fall below the fundable range may be invited to Stage 2 or recommended for funding by the Committee. The Programme Director reviews in detail any applications recommended for funding with a score below 7.
Stage 2
| Score | Range | Number of applications |
|---|---|---|
| 9.0 - 10.0 | Fundable | 0 |
| 8.0 - 8.9 | Fundable | 1 |
| 7.0 - 7.9 | Fundable | 1 |
| 6.0 - 6.9 | Fundable | 0 |
| 5.0 - 5.9 | Rejected | 0 |
| 4.0 - 4.9 | Rejected | 2 |
| 3.0 - 3.9 | Rejected | 0 |
| 2.0 - 2.9 | Rejected | 0 |
| 1.0 - 1.9 | Rejected | 0 |
Stage 1
| Score | Range | Number of applications |
|---|---|---|
| 6.0 - 6.9 | Invited | 0 |
| 5.0 - 5.9 | Rejected | 1 |
| 4.0 - 4.9 | Rejected | 3 |
| 3.0 - 3.9 | Rejected | 2 |
| 2.0 - 2.9 | Rejected | 6 |
| 1.0 - 1.9 | Rejected | 0 |