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EME Funding Committee - Decisions from the June 2019 Meeting

 

Contents

Stage 2 Applications

The EME Funding Committee recommended the following Stage 2 applications for either immediate funding or for funding subject to certain conditions.

Project Reference

Lead Applicant

Institution

Project Title

Researcher-led Call

NIHR128240

Associate Professor Timothy England

The University of Nottingham

Remote Ischaemic Conditioning After Stroke 3 (RECAST-3): A multicentre randomised controlled trial

Commissioned Call - Precision Medicine

NIHR128529

Professor David Cunningham

The Royal Marsden NHS Foundation Trust

Novel blood test to personalise Early Stage Colorectal Cancer treatment

Commissioned Call - Urothelial Cancers

NIHR128103

Professor James Catto

The University of Sheffield

Genotype of Urothelial cancer: Stratified Treatment and Oncological outcomes (GUSTO): Phase II study

Commissioned Call - Neurodegenerative Disorders

NIHR127921

Professor Ammar Al-Chalabi

King's College London

Evaluation of Triumeq as a treatment for amyotrophic lateral sclerosis: The Lighthouse 2 UK Study

Commissioned Call - Mechanisms of Action of Health Interventions

NIHR129029

Dr Candice Roufosse

Imperial College London

Mechanistic Evaluation of Treatments for Acute Antibody-Mediated Rejection of the Kidney Transplant

Commissioned Call - Functional Imaging

NIHR128494

Associate Professor Nicholas Selby

The University of Nottingham

Application of functional MRI to improve assessment of chronic kidney disease (AFiRM study)

Commissioned Call - Precision Medicine

NIHR128465

Professor Martin Wilkins

Imperial College London

Positioning Imatinib for Pulmonary Arterial Hypertension

Further information on the above projects will be provided on the EME website once the project has started.

Stage 1 Applications

The following Stage 1 applications have been shortlisted to submit a Stage 2 application for consideration by the EME Funding Committee at its next meeting.

Project Reference

Lead Applicant

Institution

Project Title

Researcher-led Call

NIHR129318

Dr Matthew Armstrong

University of Birmingham

Home-based EXercise and motivAtional program before and after Liver Transplantation: ExaLT trial

NIHR129382

Professor Amit Bahl

University Hospitals Bristol NHS Foundation Trust

Neoadjuvant chemotherapy (Gemcitabine & Cisplatin vs. Cabazitaxel & Cisplatin) with or without immunotherapy (Cemiplimab) for muscle invasive bladder cancer (MIBC): a factorial randomised controlled trial (RCT) with internal pilot

NIHR128980

Professor Waljit Singh Dhillo

Imperial College London

Using kisspeptin to trigger oocyte maturation to improve the safety of IVF treatment

Themed Call - Chronic Pain

NIHR129335

Dr Adnan Al-Kaisy

Guy's and St Thomas' NHS Foundation Trust

The Efficacy of Dorsal Root Ganglion Burst Stimulation in the Management of Complex Regional Pain Syndrome. A Multicentre, Randomised Double-Blind Sham-Controlled Study. “Typhoon”

Commissioned Call - Precision Medicine

NIHR129023

Dr Laura Coates

University of Oxford

Optimising Psoriatic Arthritis Therapy with Immunological Methods to Increase Standard Evaluation (OPTIMISE)

NIHR129268

Dr Jenny Seligmann

University of Leeds

A biomarker stratified randomized trial of chemotherapy plus cetuximab or panitumumab, versus chemotherapy alone, in the first-line treatment of RAS wild-type advanced colorectal cancer with a right-sided primary tumour location

NIHR128816

Dr Michael Pavlides

University of Oxford

Risk stratification of patients with compensated liver cirrhosis for oesophageal varices needing treatment using MRI

Commissioned Call - Dental Health - Disorders of the teeth and gums

NIHR129163

Professor Tanya Walsh

Manchester University NHS Foundation Trust

Can a near infrared light transillumination device be used to accurately detect caries in a general dental practice setting?