Stage 2 Applications
The EME Funding Committee recommended the following Stage 2 applications for either immediate funding or for funding subject to certain conditions.
Researcher-led Call
- Project ref: NIHR128240
Lead Applicant: Associate Professor Timothy England, The University of Nottingham
Remote Ischaemic Conditioning After Stroke 3 (RECAST-3): A multicentre randomised controlled trial
Commissioned Call - Precision Medicine
- Project ref: NIHR128529
Lead Applicant: Professor David Cunningham, The Royal Marsden NHS Foundation Trust
Novel blood test to personalise Early Stage Colorectal Cancer treatment
Commissioned Call - Urothelial Cancers
- Project ref: NIHR128103
Lead Applicant: Professor James Catto, The University of Sheffield
Genotype of Urothelial cancer: Stratified Treatment and Oncological outcomes (GUSTO): Phase II study
Commissioned Call - Neurodegenerative Disorders
- Project ref: NIHR127921
Lead Applicant: Professor Ammar Al-Chalabi, King's College London
Evaluation of Triumeq as a treatment for amyotrophic lateral sclerosis: The Lighthouse 2 UK Study
Commissioned Call - Mechanisms of Action of Health Interventions
- Project ref: NIHR129029
Lead Applicant: Dr Candice Roufosse, Imperial College London
Mechanistic Evaluation of Treatments for Acute Antibody-Mediated Rejection of the Kidney Transplant
Commissioned Call - Functional Imaging
- Project ref: NIHR128494
Lead Applicant: Associate Professor Nicholas Selby, The University of Nottingham
Application of functional MRI to improve assessment of chronic kidney disease (AFiRM study)
Commissioned Call - Precision Medicine
- Project ref: NIHR128465
Lead Applicant: Professor Martin Wilkins, Imperial College London
Positioning Imatinib for Pulmonary Arterial Hypertension
Further information on the above projects will be provided on the EME website once the project has started.
Stage 1 Applications
The following Stage 1 applications have been shortlisted to submit a Stage 2 application for consideration by the EME Funding Committee at its next meeting.
Researcher-led Call
- Project ref: NIHR129318
Lead Applicant: Dr Matthew Armstrong, University of Birmingham
Home-based EXercise and motivAtional program before and after Liver Transplantation: ExaLT trial - Project ref: NIHR129382
Lead Applicant: Professor Amit Bahl, University Hospitals Bristol NHS Foundation Trust
Neoadjuvant chemotherapy (Gemcitabine & Cisplatin vs. Cabazitaxel & Cisplatin) with or without immunotherapy (Cemiplimab) for muscle invasive bladder cancer (MIBC): a factorial randomised controlled trial (RCT) with internal pilot - Project ref: NIHR128980
Lead Applicant: Professor Waljit Singh Dhillo, Imperial College London
Using kisspeptin to trigger oocyte maturation to improve the safety of IVF treatment
Themed Call - Chronic Pain
- Project ref: NIHR129335
Lead Applicant: Dr Adnan Al-Kaisy, Guy's and St Thomas' NHS Foundation Trust
The Efficacy of Dorsal Root Ganglion Burst Stimulation in the Management of Complex Regional Pain Syndrome. A Multicentre, Randomised Double-Blind Sham-Controlled Study. “Typhoon”
Commissioned Call - Precision Medicine
- Project ref: NIHR129023
Lead Applicant: Dr Laura Coates, University of Oxford
Optimising Psoriatic Arthritis Therapy with Immunological Methods to Increase Standard Evaluation (OPTIMISE) - Project ref: NIHR129268
Lead Applicant: Dr Jenny Seligmann, University of Leeds
A biomarker stratified randomized trial of chemotherapy plus cetuximab or panitumumab, versus chemotherapy alone, in the first-line treatment of RAS wild-type advanced colorectal cancer with a right-sided primary tumour location - Project ref: NIHR128816
Lead Applicant: Dr Michael Pavlides
University of Oxford
Risk stratification of patients with compensated liver cirrhosis for oesophageal varices needing treatment using MRI
Commissioned Call - Dental Health - Disorders of the teeth and gums
- Project ref: NIHR129163
Lead Applicant: Professor Tanya Walsh, Manchester University NHS Foundation Trust
Can a near infrared light transillumination device be used to accurately detect caries in a general dental practice setting?