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EME Funding Committee - Decisions from the June 2019 Meeting



Stage 2 Applications

The EME Funding Committee recommended the following Stage 2 applications for either immediate funding or for funding subject to certain conditions.

Project Reference

Lead Applicant


Project Title

Researcher-led Call


Associate Professor Timothy England

The University of Nottingham

Remote Ischaemic Conditioning After Stroke 3 (RECAST-3): A multicentre randomised controlled trial

Commissioned Call - Precision Medicine


Professor David Cunningham

The Royal Marsden NHS Foundation Trust

Novel blood test to personalise Early Stage Colorectal Cancer treatment

Commissioned Call - Urothelial Cancers


Professor James Catto

The University of Sheffield

Genotype of Urothelial cancer: Stratified Treatment and Oncological outcomes (GUSTO): Phase II study

Commissioned Call - Neurodegenerative Disorders


Professor Ammar Al-Chalabi

King's College London

Evaluation of Triumeq as a treatment for amyotrophic lateral sclerosis: The Lighthouse 2 UK Study

Commissioned Call - Mechanisms of Action of Health Interventions


Dr Candice Roufosse

Imperial College London

Mechanistic Evaluation of Treatments for Acute Antibody-Mediated Rejection of the Kidney Transplant

Commissioned Call - Functional Imaging


Associate Professor Nicholas Selby

The University of Nottingham

Application of functional MRI to improve assessment of chronic kidney disease (AFiRM study)

Commissioned Call - Precision Medicine


Professor Martin Wilkins

Imperial College London

Positioning Imatinib for Pulmonary Arterial Hypertension

Further information on the above projects will be provided on the EME website once the project has started.

Stage 1 Applications

The following Stage 1 applications have been shortlisted to submit a Stage 2 application for consideration by the EME Funding Committee at its next meeting.

Project Reference

Lead Applicant


Project Title

Researcher-led Call


Dr Matthew Armstrong

University of Birmingham

Home-based EXercise and motivAtional program before and after Liver Transplantation: ExaLT trial


Professor Amit Bahl

University Hospitals Bristol NHS Foundation Trust

Neoadjuvant chemotherapy (Gemcitabine & Cisplatin vs. Cabazitaxel & Cisplatin) with or without immunotherapy (Cemiplimab) for muscle invasive bladder cancer (MIBC): a factorial randomised controlled trial (RCT) with internal pilot


Professor Waljit Singh Dhillo

Imperial College London

Using kisspeptin to trigger oocyte maturation to improve the safety of IVF treatment

Themed Call - Chronic Pain


Dr Adnan Al-Kaisy

Guy's and St Thomas' NHS Foundation Trust

The Efficacy of Dorsal Root Ganglion Burst Stimulation in the Management of Complex Regional Pain Syndrome. A Multicentre, Randomised Double-Blind Sham-Controlled Study. “Typhoon”

Commissioned Call - Precision Medicine


Dr Laura Coates

University of Oxford

Optimising Psoriatic Arthritis Therapy with Immunological Methods to Increase Standard Evaluation (OPTIMISE)


Dr Jenny Seligmann

University of Leeds

A biomarker stratified randomized trial of chemotherapy plus cetuximab or panitumumab, versus chemotherapy alone, in the first-line treatment of RAS wild-type advanced colorectal cancer with a right-sided primary tumour location


Dr Michael Pavlides

University of Oxford

Risk stratification of patients with compensated liver cirrhosis for oesophageal varices needing treatment using MRI

Commissioned Call - Dental Health - Disorders of the teeth and gums


Professor Tanya Walsh

Manchester University NHS Foundation Trust

Can a near infrared light transillumination device be used to accurately detect caries in a general dental practice setting?