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EME Funding Committee - Decisions from the June 2019 Meeting


Published: 02 August 2019

Version: 1.0 - August 2019

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MRC-NIHR funding collaboration

Stage 2 Applications

The EME Funding Committee recommended the following Stage 2 applications for either immediate funding or for funding subject to certain conditions.

Researcher-led Call

  • Project ref: NIHR128240
    Lead Applicant: Associate Professor Timothy England, The University of Nottingham
    Remote Ischaemic Conditioning After Stroke 3 (RECAST-3): A multicentre randomised controlled trial

Commissioned Call - Precision Medicine

  • Project ref: NIHR128529
    Lead Applicant: Professor David Cunningham, The Royal Marsden NHS Foundation Trust
    Novel blood test to personalise Early Stage Colorectal Cancer treatment

Commissioned Call - Urothelial Cancers

  • Project ref: NIHR128103
    Lead Applicant: Professor James Catto, The University of Sheffield
    Genotype of Urothelial cancer: Stratified Treatment and Oncological outcomes (GUSTO): Phase II study

Commissioned Call - Neurodegenerative Disorders

  • Project ref: NIHR127921
    Lead Applicant: Professor Ammar Al-Chalabi, King's College London
    Evaluation of Triumeq as a treatment for amyotrophic lateral sclerosis: The Lighthouse 2 UK Study

Commissioned Call - Mechanisms of Action of Health Interventions

  • Project ref: NIHR129029
    Lead Applicant: Dr Candice Roufosse, Imperial College London
    Mechanistic Evaluation of Treatments for Acute Antibody-Mediated Rejection of the Kidney Transplant

Commissioned Call - Functional Imaging

  • Project ref: NIHR128494
    Lead Applicant: Associate Professor Nicholas Selby, The University of Nottingham
    Application of functional MRI to improve assessment of chronic kidney disease (AFiRM study)

Commissioned Call - Precision Medicine

  • Project ref: NIHR128465
    Lead Applicant: Professor Martin Wilkins, Imperial College London
    Positioning Imatinib for Pulmonary Arterial Hypertension

Further information on the above projects will be provided on the EME website once the project has started.

Stage 1 Applications

The following Stage 1 applications have been shortlisted to submit a Stage 2 application for consideration by the EME Funding Committee at its next meeting.

Researcher-led Call

  • Project ref: NIHR129318
    Lead Applicant: Dr Matthew Armstrong, University of Birmingham
    Home-based EXercise and motivAtional program before and after Liver Transplantation: ExaLT trial
  • Project ref: NIHR129382
    Lead Applicant: Professor Amit Bahl, University Hospitals Bristol NHS Foundation Trust
    Neoadjuvant chemotherapy (Gemcitabine & Cisplatin vs. Cabazitaxel & Cisplatin) with or without immunotherapy (Cemiplimab) for muscle invasive bladder cancer (MIBC): a factorial randomised controlled trial (RCT) with internal pilot
  • Project ref: NIHR128980
    Lead Applicant: Professor Waljit Singh Dhillo, Imperial College London
    Using kisspeptin to trigger oocyte maturation to improve the safety of IVF treatment

Themed Call - Chronic Pain

  • Project ref: NIHR129335
    Lead Applicant: Dr Adnan Al-Kaisy, Guy's and St Thomas' NHS Foundation Trust
    The Efficacy of Dorsal Root Ganglion Burst Stimulation in the Management of Complex Regional Pain Syndrome. A Multicentre, Randomised Double-Blind Sham-Controlled Study. “Typhoon”

Commissioned Call - Precision Medicine

  • Project ref: NIHR129023
    Lead Applicant: Dr Laura Coates, University of Oxford
    Optimising Psoriatic Arthritis Therapy with Immunological Methods to Increase Standard Evaluation (OPTIMISE)
  • Project ref: NIHR129268
    Lead Applicant: Dr Jenny Seligmann, University of Leeds
    A biomarker stratified randomized trial of chemotherapy plus cetuximab or panitumumab, versus chemotherapy alone, in the first-line treatment of RAS wild-type advanced colorectal cancer with a right-sided primary tumour location
  • Project ref: NIHR128816
    Lead Applicant: Dr Michael Pavlides
    University of Oxford
    Risk stratification of patients with compensated liver cirrhosis for oesophageal varices needing treatment using MRI

Commissioned Call - Dental Health - Disorders of the teeth and gums

  • Project ref: NIHR129163
    Lead Applicant: Professor Tanya Walsh, Manchester University NHS Foundation Trust
    Can a near infrared light transillumination device be used to accurately detect caries in a general dental practice setting?