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NIHR SPARC (Short Placement Award for Research Collaboration): Where Can I Go?

 

Contents

You can undertake a SPARC placement anywhere across the NIHR as long as you get agreement with the host first - the list below is by no means exhaustive. What follows are some ideas that have been suggested as potential placements. You will still need to contact the host and arrange this yourself, but we hope this gives you some idea of what might be possible. This document will continue to be updated as we receive more ideas for placements.

Where can I go?

NIHR Infrastructure

Biomedical Research Centres (BRCs)

Bristol BRC 

Webpage: https://www.bristolbrc.nihr.ac.uk/

The Bristol BRC comprises 5 themes: Cardiovascular Research, Nutrition, Surgical Innovation, Perinatal and Reproductive Health and Mental Health.

Alongside these, it has noteworthy expertise in epidemiology, biostatistics and evidence synthesis.

The two departments in the newly formed Bristol Medical School have an excellent track record of supporting trainees and training at all levels and run a world class short course programme.

We would be delighted to host doctoral students and/or postdoctoral researchers who would be interested in coming to Bristol.

Guys and St Thomas BRC 

Webpage: http://www.guysandstthomasbrc.nihr.ac.uk/

At our BRC we aim to:

  • Lead the revolution in advanced therapeutics
  • Address research priority areas
  • Deliver systems leadership for maximum impact

We have nine research themes each led by an expert in the field:

  •         Cardiovascular disease – Professor Ajay Shah
  •         Cutaneous Medicine – Professor Jonathan Barker
  •         Genomic Medicine – Professor Richard Trembath
  •         Infection and Immunity – Professor Mike Malim
  •         Imaging Sciences - Professor Sebastien Ourselin
  •         Transplantation – Professor Steven Sacks
  •         Oral Health – Professor Paul Sharpe
  •         Regenerative medicine and cellular therapy - Professor Fiona Watt
  •         Women and Children’s Health – Professor Lucilla Poston

    You can find out more about each on the research themes section of our website - http://www.guysandstthomasbrc.nihr.ac.uk/research/research-themes

    In addition to our research themes there are projects within our MHRA Accredited Clinical Research Facility and our research platforms, such as our Advanced therapies manufacturing platform and our Flow Cytometry platform - http://www.guysandstthomasbrc.nihr.ac.uk/research-platforms/

Nottingham BRC

Webpage: https://nottinghambrc.nihr.ac.uk/

  1.       Advanced imaging through MRI, MRS using 1.5T, 3T and 7T imaging
  2.       Biomarker development which includes computational and molecular pathology pipelines to transform multiplatform biomarker      testing into clinical decision making tools.
  3.       Microbiology and synthetic biology research includes our Clostridia Research Group and H. pylori group and the Pseudomonas group
  4.       Musculoskeletal Ageing Research facilitates in vivo human, whole body physiology investigations
  5.       Population based cohort studies (4 REF2014 Impact case studies) underpin epidemiology research

Southampton BRC

Webpage: http://www.uhs.nhs.uk/ClinicalResearchinSouthampton/Research/Facilities/NIHR-Southampton-Biomedical-Research-Centre/NIHRSouthamptonBiomedicalResearchCentre.aspx 

Main themes: Nutrition and Respiratory health

The centre has two main, linked, themes:

1) Lifecourse Nutrition, Lifestyle and Health, for further information please contact Dr Mark Johnson (m.johnson@soton.ac.uk)

2) Respiratory and Critical Care, for further information please contact Dr Karl Staples (k.staples@soton.ac.uk). We provide a vibrant environment supported by enthusiastic and caring supervisors and an effective mentorship scheme.

Lifecourse Nutrition, Lifestyle and Health

The Lifecourse Nutrition, Lifestyle and Health theme addresses major challenges to our nation's health including childhood obesity, liver disease and alcohol-related illness, cancer linked to obesity and healthy ageing. Work in this theme examines these issues at three stages of life: 1) Early life, from before pregnancy to adolescence; 2) Adulthood; and 3) Older age. For further information, contact Professor Keith Godfrey (kmg@mrc.soton.ac.uk).

 Expertise and strengths for placement:

The Lifecourse Nutrition, Lifestyle and Health theme team offers the following:

  • Expertise in nutrition and epigenetics
  • Skills in the assessment of nutrition and lifestyle related liver disease
  • Experience of mother-offspring nutritional cohort and intervention studies
  • Expertise in nutrition as it relates to healthy ageing
  • Training in communicating research stories to teenagers, as part of work to strengthen nutrition literacy in young people.

 Respiratory and Critical Care

The Respiratory and Critical Care Theme addresses common problems that affect millions of people like asthma, lung cancer and chronic obstructive pulmonary disorder (COPD), tackles rare lung diseases for which therapies are limited, and will discover new ways of improving the management of critically ill patients. Work on these topics involves three aspects, from better prevention of disease, through earlier and more accurate diagnoses, to developing treatments personalised to each individual including managing end-of-life care with dignity. For further information, contact Professor Ratko Djukanovic (R.Djukanovic@soton.ac.uk).

 Expertise and strengths for placement:

  • Full breadth of cutting-edge research, from basic (laboratory-based) to clinical science, across all the major lung disease areas (respiratory allergy, respiratory infections, chronic airways diseases (asthma, COPD, bronchiectasis, cough), critical care, rare lung diseases (idiopathic pulmonary fibrosis, primary ciliary dyskinesia, cystic fibrosis), lung cancer.
  • Expertise in key disease processes across the life-course (e.g. asthma, cystic fibrosis, bronchiectasis, and intensive care in children and adults).
  • An excellent inter-disciplinary research environment: collaborations with engineers, chemists, mathematicians, psychologists, respectively to build novel methods for study of disease ex vivo (experiments on relevant tissue outside the body), discover and test new chemicals to intervene in critical disease pathways, develop new mathematical models to group different types of data and thereby identify and elucidate the mechanisms of new types of disease groups, and develop psychological interventions to improve management of chronic diseases.
  • Close collaboration between basic and clinician scientists, ensuring availability of patient samples to study disease mechanisms from both a scientific and clinical perspective. This provides excellent opportunities for trainee scientists and clinicians to learn about each other’s areas of interest.

Cross-cutting themes

Three important areas of research are common to our nutrition and respiratory themes:

  • Data science: Using large amounts of clinical and research data to improve treatments and health
  • Microbial science: Fighting microbial infections and overcoming antibiotic resistant bacteria
  • Behavioural science: Supporting people in healthy behaviours and choices

Training in these cross-cutting themes is led by Kay Mitchell (K.Mitchell@soton.ac.uk).

Data science                                                  

With patient agreement, we are making the most of patient information available in the NHS system and from research studies. We aim to help doctors make better, faster decisions on individuals’ treatment through new approaches to combining and analysing data from, for example, admissions to hospital, scans, genetic and biochemical results. For further details, contact Professor Anneke Lucassen (a.lucassen@soton.ac.uk).

 Expertise and strengths for placement:

  • Integrating omics data for personalized medicine
  • NHS data standards for research
  • Machine learning approaches to disease stratification
  • Ethical impacts of research using data

Microbial science

A growing number of bacteria and fungi resistant to antibiotic drugs threaten to make currently treatable infections and routine surgery lethal. We’re combining genetic techniques to identify new drugs with an approach exploring use of ‘good’ bacteria in the gut and upper airways to fight infection and improve health. To do this we’ve brought together experts in engineering, microbiology and physical sciences, and initiated ground-breaking studies of infectious diseases. For further details, contact Professor Rob Read (R.C.Read@soton.ac.uk).

Expertise and strengths for placement:

  • Experimental human challenge: design, recruitment and procedures
  • Microbiome analysis
  • Experimental models of human infection
  • Biofilm measurement and manipulation

 

Behavioural science

 

Supporting people in making choices that improve their health, and that of their families, is critical to wellbeing and our productivity as a nation. Through a new Centre for Participatory Medicine, we are combining digital, educational and face-to-face methods of offering support into new ways of improving control of respiratory diseases and reducing obesity and malnutrition. For further details, contact Professor Mary Barker (meb@mrc.soton.ac.uk).

 Expertise and strengths for placement:

  • Expertise in digital intervention development and testing
  • Skills in running effective PPI
  • Experience of research in educational environments
  • Training in skills to support behaviour change in individuals and organisations 

Maudsley BRC

Webpage: https://www.maudsleybrc.nihr.ac.uk

Theme 1: Novel Therapeutics

Theme Lead: Professor Allan Young

Project Team: Centre for Affective Disorders:  CRiB Study

Prof. Allan Young collaborating with senior academics across IoPPN and clinicians in SLaM.

Project Lead: Professor Allan Young

Areas of expertise / specialist skills offered by the placement opportunity: 

Clinical Trials, Psychological Therapies, Cognitive Remediation, Neuroimaging, Bipolar Disorder Clinical interviewing, neuropsychological assessment, neuroimaging, data analysis

Project website address:

https://www.kcl.ac.uk/ioppn/depts/pm/research/CfAD/The-CRiB-study.aspx 

Theme 2: Substance Use

Theme Lead: Professor Sir John Strang

Project Team: The Heroin Overdose and Reversal Experimental Study group: Professor Sir John Strang working with other professors and senior academics within the Addictions group and collaborators.

Project Lead: Professor Sir John Strang , working with Dr Caroline Jolley, Clinical Senior Lecturer in Respiratory Medicine; and with Prof Ben Forbes and Dr Paul Royall (Institute Pharmaceutical Sciences) for development of prototype overdose reversal medications.  

Areas of expertise / specialist skills offered by the placement opportunity: Development of skills working on the interface between addictions studies and respiratory and emergency medicine, also experimental studies developed and undertaken in partnership with patient groups and active clinicians.

For overview of the rationale, see 

https://www.dropbox.com/s/ohkapcwk0xlsk3y/KCL-distancelearning-thenaloxonestory-2016-Final_Edit_M5_W2_IoPPN_revised_tosend.mp4?dl=0 

Theme 3: Biomarkers & Genomics

Theme Lead: Professor Cathryn Lewis

Project Team: Statistical Genetics Unit

Project Lead: Professor Cathryn Lewis

Areas of expertise / specialist skills offered by the placement opportunity: Statistical genetics, genetic association testing, polygenic risk scores. In collaboration with the trainee, we will develop a project based on polygenic risk scores for psychiatric and neuropsychiatric disorders, exploring how these could be moved from research studies to the clinic.   

Project website address:

https://www.kcl.ac.uk/lsm/research/divisions/gmm/departments/mmg/researchgroups/clewis/sgu/index.aspx  

Theme 4: Clinical and Population Informatics

Theme Lead: Professor Robert Stewart

Project Team: Clinical Informatics in the BRC Nucleus

Project Lead: Professor Robert Stewart

Areas of expertise / specialist skills offered by the placement opportunity: Analysis and interpretation of ‘big’ healthcare data. Applied natural language processing. 

Project website address:

http://www.maudsleybrc.nihr.ac.uk/facilities/clinical-record-interactive-search-cris/  

Theme 5: Neuroimaging

Theme Lead: Professor Steve Williams

Project Team: Neuroimaging department at the Institute of Psychiatry, Psychology and Neuroscience.

Project Lead: Professor Steve Williams

Areas of expertise / specialist skills offered by the placement opportunity: Exposure to psychiatric neuroimaging research across the lifespan. S/he will be given the opportunity to engage in their choice of one or more projects from a choice of over 80 protocols currently underway.  

Project website address:

https://www.kcl.ac.uk/ioppn/depts/neuroimaging/index.aspx 

Great Ormond Street Hospital BRC 

Webpage: http://www.gosh.nhs.uk/research-and-innovation/nihr-great-ormond-street-hospital-brc

The National Institute for Health Research Great Ormond Street Hospital Biomedical Research Centre (NIHR GOSH BRC) aims to accelerate discoveries into the basis of childhood rare diseases and to develop novel diagnostics, imaging techniques and new treatments, including cellular and gene therapies.

The NIHR GOSH BRC is the only centre of its kind dedicated to paediatric research with research focused around the following four key research themes; Gene, Stem, and Cellular Therapies, Genomics and Systems Medicine, Novel Therapies and their Translation into Childhood Diseases and Advanced Treatments for Structural Malformation and Tissue Damage.

The cross-cutting themes provide specialist knowledge and expertise across the GOSH BRC, helping them to undertake and deliver the best research possible. The themes consist of; Rare diseases cohorts, Experimental Medicine Academy, Clinical Research Facility High Intensity Inpatient trials and Translational Research and Enterprise Accelerator.

For more information on the NIHR GOSH BRC please visit our website:http://www.gosh.nhs.uk/research-and-innovation/nihr-great-ormond-street-hospital-brc

University College London Hospitals BRC 

Webpage: http://www.uclhospitals.brc.nihr.ac.uk/

Our UCLH BRC research themes are comprehensive and internationally recognised:

  • Cancer
  • Cardiovascular disease
  • Inflammation, Immunity and Immunotherapeutics
  • Neurological disease
  • Dementia
  • Mental health
  • Obesity
  • Oral health and disease
  • Deafness and hearing

These research themes are underpinned by cross-cutting themes:

  • Healthcare Engineering and Imaging
  • Healthcare Informatics, Genomics/Omics, Data Science
  • Education – the BRC Experimental Medicine Academy
  • Patient and Public Involvement, Engagement and Communications

Sheffield BRC 

Webpage: http://sheffieldbrc.nihr.ac.uk/research-themes/

The National Institute for Health Research (NIHR) Sheffield Biomedical Research Centre (BRC) is a research partnership between the University of Sheffield and Sheffield Teaching Hospitals NHS Foundation Trust, dedicated to improving the treatment and care of people living with chronic neurological disorders.  Visit our webpage for more information here

NIHR Sheffield BRC has NIHR Infrastructure Short Placement Award for Research Collaboration (SPARC) opportunities in the following areas:

Predictive medicine technologies. These approaches are particularly effective when mechanistic knowledge has a significant biophysics component. INSIGNEO will host fellows interested in learning how to integrate and model quantitative phenotyping of balance, movement, and muscle force expression, combined with biomarker data from target diseases. Specific placements may cover: a) Instrumental quantification of neuromuscular and neuromotor deficits, b) Use of wearable sensors as part of a clinical motor functional assessment, c) Patient-specific modelling as a tool to quantify neuromotor degeneration. http://insigneo.org

Advanced Imaging. The Sheffield BRC will host fellows interested in applying advanced imaging techniques to provide diagnosis, prognosis, provision of mechanistic information, and imaging biomarkers to aid development and evaluation of new therapeutic interventions. Specific placements may cover different MR sub-modality techniques, acquisition protocols and analysis tools including:31P, 22Na multinuclear spectroscopy; 1H spectral editing; endogenous perfusion, macrovascular flow, advanced diffusion, fMRI & resting-state fMRI; multi-contrast carotid plaque characterisation. http://sitran.org/

Genomics and Bioinformatics. Clinical research centres are now routinely generating genomics and omics datasets that necessitate specialist training, not taught as part of traditional medical curriculum. We address the need for quantitative and computational skills to enable clinical researchers to design appropriate experiments, interpret and explore their data, build vocabulary and so forge more effective collaborations with Bioinformaticians. The Sheffield Bioinformatics Core, together with the cross-cutting genome analytics group,

as part of the NIHR Sheffield Biomedical Research Centre, provides a rich training environment for and best-practice data analysis in clinical genomics and research. We welcome fellows with an interest in developing their skills in this area to apply to their own research area. http://sitran.org/

If interested in a SPARC opportunity at NIHR Sheffield BRC please contact the training lead Oliver Bandmann (o.bandmann@sheffield.ac.uk) or the BRC Manager Miss Jodie Keyworth (Jodie.keyworth@sth.nhs.uk)

Imperial BRC

Webpage: https://imperialbrc.nihr.ac.uk/

The NIHR Imperial BRC harnesses the scientific power of Imperial College London with Imperial College Healthcare Trust, the UK’s largest group of research-intensive hospitals. The aim of our BRC is to translate most rapidly and efficiently our scientific discoveries into the clinic, through our five hospitals, serving a highly ethnically diverse population of 2.3M in North-West London.

Our BRC activities are focussed on developing new devices, diagnostics, new therapies and in analysing and integrating health data, across 8 research themes and 4 cross cutting themes.

Research Themes:

Cross Cutting Themes:

Further details can be found on our website which details the themes and facilities as well as some examples of recent research we have completed successfully : Webpage: https://imperialbrc.nihr.ac.uk/

If you are interested in a SPARC opportunity at NIHR Imperial BRC, please contact BRCOfficer@imperial.ac.uk.

Leeds BRC

Webpage: www.leedsbrc.nihr.ac.uk 

The Leeds BRC is a collaboration between Leeds Teaching Hospitals Trust and the University of Leeds.  The Centre is built around the existing strengths in rheumatology, bioengineering, regenerative medicine and imaging.

The vision for the Leeds Musculoskeletal Biomedical Research Centre (BRC) is that through accurate detection and early diagnosis, we can identify individually targeted, cost-effective therapies for musculoskeletal patients for both IMIDs and OA.  This personalised approach will be driven by two clinical challenges

  1. To identify people who are at risk of developing inflammatory arthritis in order to prevent development of inflammatory complications and develop targeted, safe treatments
  2. To improve the treatment of OA to provide fifty active years after fifty in the ageing population

Our research is focused on two themes which are driven by key challenges for the burden of MSK:  early detection and optimal management of immune mediated inflammatory diseases (IMID; work streams 1-4) and disease progression prevention and improving the treatment of osteoarthritis (OA; work streams 5-7). 

Our workstreams consist of the following:

Immune Mediated Inflammatory Diseases

  1. At Risk of Developing Rheumatoid Arthritis
  2. Immunotherapies in Rheumatoid Arthritis
  3. Interventions based on stratified prognosis for Psoriatic Arthritis and Connective Tissue Disease
  4. Drug Repurposing and treatment toxicity for Immune Mediated Inflammatory Diseases

Osteoarthritis

  1.   Longer lasting joint replacements
  2.   Acellular scaffolds and regenerative devices for treatment of Osteoarthritis
  3.   Non-surgical treatments for Osteoarthritis

Specialist facilities include

  •   Research dedicated Musculoskeletal Imaging Facilities, including 3T MRI and Ultrasound
  •   State of the Art Gait and Motion Analysis Laboratory
  •   Leeds Institute for Rheumatic and Musculoskeletal Medicine
  •   Institute for Medical and Biological Engineering
  •   Psychometric Laboratory (Rasch Analysis)
  •   Leeds Institute for Clinical Trials Research

Newcastle BRC

Webpage: http://www.newcastlebrc.nihr.ac.uk/research-themes/

  • NIHR Newcastle BRC have particular expertise in relation to ageing and long-term conditions.
  • Research activity includes projects relating to care of older people with ageing syndromes including sarcopenia and to the following themes relevant to ageing:
    • Dementia (including Dementia with Lewy Bodies)
    • Liver disease
    • Musculoskeletal disease
    • Neuromuscular disease (including mitochondrial disease)
    • Skin and oral disease
    • Ageing syndromes;  such as sarcopenia, frailty and multimorbidity including trials related to these conditions. For more information please contact Professor Avan Sayer or Professor Miles Witham
  • Our BRC has an expertise in relation to patient and public involvement in research design, delivery and dissemination
  • Our researchers have access to world-class facilities based at the Campus for Ageing and Vitality, Newcastle University Medical School and Newcastle upon Tyne Hospitals. See more at https://www.newcastlebrc.nihr.ac.uk/about-us/facilities/

Royal Marsden and the Institute of Cancer Research BRC

Webpage: https://www.cancerbrc.org/our-research

The Biomedical Research Centre at The Royal Marsden and Institute of Cancer Research comprises six research themes:

 There are also two cross-cutting themes:

If interested in a SPARC opportunity, please contact the Training Lead, Dr Naureen Starling (Naureen.Starling@rmh.nhs.uk), the Clinical Research Operations Manager, Mark Terry (Mark.Terry@rmh.nhs.uk)  and the relevant Theme Lead as outlined on the website.

Leicester BRC

Webpage: https://www.leicesterbrc.nihr.ac.uk/

The NIHR Leicester BRC is hosted by Leicester’s Hospitals, in partnership with the University of Leicester and Loughborough University.

The NIHR Leicester BRC is at the frontier of research into illnesses linked to respiratory conditions, cardiovascular disease, Type 2 diabetes, chronic kidney disease and the consequences of inactivity. Our overall purpose is to translate scientific breakthroughs in these areas into diagnostic tests, preventions and life-saving treatments for our patients.

Our centre consists of three research themes:

  •         Cardiovascular
  •         Lifestyle
  •         Respiratory

 1 cross cutting theme:

  •         Precision Medicine

Barts BRC

Webpage: https://www.qmul.ac.uk/whri/research/cardiovascular/nihr-barts-biomedical-research-centre-/

The NIHR Barts Biomedical Research Centre is a joint partnership between Barts Health NHS Trust and Queen Mary University of London.

Research Themes:

Inherited Cardiovascular Disorders

Our translational genomics research platform is exceptional with one the largest rare inherited disorders clinical services. Our strategy capitalises upon the 100,000 Genomes Project.

Research Lead: Panos Deloukas

Expertise and strengths for placement:

  •       Expertise in genetic markers for coronary heart disease
  •       Integrating multiomics and phenotyping for medicine

For further details, please contact ProfessorPanos (Panagiotis)Deloukas (p.deloukas@qmul.ac.uk)

Cardiovascular Devices and Innovative Trials

This research theme aims to exploit the potential of translational non-invasive/implantable devices by contributing to the establishment a UK based one-stop device centre that integrates a faculty of world-leading academics, bio-engineers, and industry partnerships in collaboration with Yale University, USA.

Research Team: John Deanfield , Andreas Baumbach, Alexandra Lansky, Anthony Mathur

Expertise and strengths for placement:

  •       Expertise in innovative trials, cardiovascular devices and new technology
  •       Strong academic and industry network

For further details, please contact Professor Anthony Mathur (a.mathur@qmul.ac.uk)

Cross-Cutting Themes:

Barts BioResource (Incorporating Advanced Cardiovascular Imaging and Bioinformatics)

The BBR is home to one of the UKs most cutting-edge advanced cardiovascular imaging and bioinformatics facilities with its infrastructure based on a state-of–the-art multi-petabyte data centre platform.

Research Lead: Steffen Petersen

 Expertise and strengths for placement:

  •       Expertise in phenotyping using advanced cardiovascular imaging
  •       Bioinformatics skills in BioResource

For further details, please contact Professor Steffen Petersen (s.e.petersen@qmul.ac.uk) 

 

Oxford BRC

Webpage: https://oxfordbrc.nihr.ac.uk

The Oxford BRC focuses on translational research, meaning first time studies of medical innovations in patients, to improve healthcare delivery for all. Our research is divided into 20 research themes covering all areas of therapy and includes developing new technology and devices as well as behavioural approaches to healthcare.

Antimicrobial Resistance & Modernising Microbiology

Cardiovascular

Clinical Informatics & Big Data

Diabetes & Metabolism

Gastroenterology & Mucosal Immunity

Genomic Medicine

Haematology & Stem Cells

Imaging

Molecular Diagnostics

Multi-modal Cancer Therapies

Multimorbidity & Long-Term Conditions

Musculoskeletal

Neurological Conditions

Obesity, Diet & Lifestyle

Respiratory

Stroke & Vascular Dementia

Surgical Innovation & Evaluation

Technology & Digital Health

Vaccines for Emerging & Endemic Diseases

Partnerships for Health, Wealth & Innovation

For anyone interested in a SPARC opportunity in Oxford please contact either of the training leads Professor Sarah Rowland-Jones sarah.rowland-jones@ndm.ox.ac.uk or Dr Denise Best denise.best@medsci.ox.ac.uk and the Oxford BRC Education and Training Manager Dr Karen Bell karen.bell@medsci.ox.ac.uk

Manchester BRC

Webpage: https://www.manchesterbrc.nihr.ac.uk/

Our Manchester BRC research themes include:

Advanced Radiotherapy:

Our Advanced Radiotherapy research team is working to embrace technological advances and develop biomarkers to predict the effectiveness of different types of radiation and drug-radiation combinations, as well as helping to minimise the risk of long-term side effects.

Expertise & strengths for placement opportunities:

  • Personalised targeting of hypoxia for radiotherapy patients
  • Developing new radiotherapy-immunotherapy combinations
  • Improving radiation delivery
  • Identifying the genetic basis for benefit from protons

Contact: rebecca.m.elliott@manchester.ac.uk

Cancer Prevention and Early Detection:

Our research will reduce the burden of common cancers with a strong inherited component. We will develop screening strategies and biomarkers to identify cancer sooner, match an individual to the prevention treatment most likely to work for them and, in some cases, our work will even help to prevent conditions progressing into cancer in the first place.

  • Expertise & strengths for placements opportunities:
  • Developing and improving models for risk stratification
  • Obesity-related cancers
  • Developing new imaging and molecular biomarkers
  • Early detection

Our themes training leads are Prof Andrew Renehan (andrew.renehan@btinternet.com) and Dr Emma Crosbie.

Dermatology:

Research is truly translational and reflects the bedside-to-bench approach; we use qualitative and quantitative methodologies to advance our understanding, and treatment of, human skin disease.

Expertise & strengths for placement opportunities:

  • Psoriasis and inflammatory skin disease
  • The photodermatoses (disease mediated via the skin’s interactions with sunlight)
  • Hair biology including alopecia
  • Wound healing

For more information, contact the Dermatology theme training lead Professor Rachel Watson (rachel.watson@manchester.ac.uk).

Cancer Precision Medicine:

The Manchester NIHR BRC Cancer Precision Medicine theme focusses on playing to our international strengths and includes developing biomarkers to support the use of novel treatments aimed at awakening the patient’s immune system to fight their cancer, so we know which patients to treat and minimise risk of treatment toxicities.

Expertise & strengths for placement opportunities:

  • Treatment selection and monitoring of treatment response
  • Optimising immunotherapies
  • Monitoring residual disease

For more information, contact the Cancer Precision Medicine theme training lead Dr Robert Clarke (robert.clarke@manchester.ac.uk)

Hearing Health:

The Manchester NIHR BRC Hearing Health theme research programme spans prevention, diagnosis, and treatment. It will improve the lives of children and adults by preventing potentially devastating congenital deafness, diagnosing acquired age-related deficits and developing new treatments.

Expertise & strengths for placement opportunities:

  • Developing genetic and genomic solutions
  • Optimised assessment and diagnosis
  • Diagnosing paediatric auditory deficit
  • Developing engineering solutions and optimising outcomes

For more information, contact the Hearing Health theme training lead Dr Piers Dawes (Piers.Dawes@manchester.ac.uk)

Musculoskeletal:

The Manchester NIHR BRC Musculoskeletal theme has a strong track record of musculoskeletal research having had one of only three musculoskeletal NIHR Biomedical Research Units (BRU) previously, which undertook translational clinical research in musculoskeletal disorders. The BRU work forms the basis from which the research described in the BRC musculoskeletal theme is built.

Expertise & strengths for placements opportunities:

  • Inflammatory arthritis
  • Childhood arthritis
  • Connective tissue diseases
  • Degenerative joint disease

For more information, contact the Musculoskeletal theme training lead Dr Ben Parker (Ben.Parker@mft.nhs.uk)

Respiratory:

The Manchester NIHR BRC Respiratory theme research will build a better understanding of the underlying causes of these conditions, develop blood and sputum tests, as well as biomarkers in breath, which detect and more accurately characterise respiratory disease and infection. This will enable an earlier and more personalised approach to treatment and test new drug compounds aimed at novel targets to cure or improve serious lung diseases and minimise symptoms.

Expertise & strengths for placements opportunities:

  • COPD
  • Improving respiratory symptoms
  • Asthma
  • Respiratory infections

For more information, contact theme training lead Dr Riina Richardson (Riina.Richardson@manchester.ac.uk)

These research themes are underpinned by cross-cutting themes:

Informatics and Data Sciences:

The Manchester NIHR BRC Informatics and Data Sciences theme research involves patient-driven data from mobile and wearable technologies and using such technologies enable frequent measurement of disease and lifestyle patterns. Computerised connections between patients, clinicians and researchers also provide smarter ways to run experiments.

Expertise & strengths for placement opportunities:

  • Drives of change – inefficient silos of discovery and experimentation
  • Target position – research strengths borrowed across themes
  • Disruptive advance – integrative system-wide methodology

For more information, contact the BRC Training Coordinator Jane Crosbie (jane.crosbie@manchester.ac.uk)

Biomarker Platforms:

The Manchester NIHR BRC Biomarker Platforms research will use biomarkers to develop tests and techniques (including imaging, genomic, DNA or blood protein measurements) that can be used to aid clinical decisions/stratify patients into specific groups so they can receive the most appropriate care.

  • Expertise and strengths for placement opportunities:
  • Biomarker discovery and development with the Research Themes;

Accelerating the biomarker discovery to clinical use through our closely aligned infrastructure.

For more information, contact theBRC Training Coordinator Jane Crosbie (jane.crosbie@manchester.ac.uk)

Rapid Translation Incubator:

The Manchester NIHR BRC Rapid Translational Incubator is responsible for signposting researchers to operational support and providing oversight to ensure that research is rapidly translated into clinical practice. The RTI brings together key infrastructure essential to the design and delivery of clinical studies, as well as the commercialisation of new healthcare products.

For more information, contact the BRC Training Coordinator Jane Crosbie (jane.crosbie@manchester.ac.uk).

We would be delighted to host early stage researchers who would be interested in coming to Manchester.

Cambridge BRC

Webpage: https://cambridgebrc.nihr.ac.uk/

 

A partnership between Cambridge University Hospitals and the University of Cambridge.  Based on the Cambridge Biomedical Campus, it combines on a single site scientific research in world-class institutes, patient care in NHS hospitals and drug discovery in pharmaceutical companies.

Research Themes

Research at the Cambridge Biomedical Research Centre is divided into a number of therapeutic areas described as themes with several cross cutting research themes. The core priority for the NIHR Cambridge Biomedical Research Centre is translational medicine, delivering science from the bench to the bedside.

Antimicrobial resistance - Theme lead: Professor Gordon Dougan

Cancer - Theme lead: Professor Richard Gilbertson

Cardiovascular and respiratory disease - Theme lead: Professor Nick Morrell

Dementia and neurodegenerative disorders - Theme lead: Professor Roger A Barker

Gastrointestinal disease - Theme lead: Professor Arthur Kaser

Integrative genomics - Theme lead: Professor Lucy Raymond

Mental health - Theme lead: Professor Ed Bullmore

Metabolism, endocrinology and bone - Theme lead: Professor Sir Stephen O’Rahilly

Neuroscience - Theme lead: Professor Patrick Chinnery FMedSci

Nutrition diet and lifestyle - Theme lead: Professor Nick Wareham

Population and quantitative science - Theme lead: Professor John Danesh

Transplantation and regenerative medicine - Theme lead: Professor Ludovic Vallier

Women’s health and paediatrics - Theme lead: Professor Gordon Smith and Theme lead: Professor David Rowitch

Cross-cutting research themes

The cross cutting themes provide specialist knowledge and expertise across the whole of the Biomedical Research Centre helping them to undertake and deliver the best research possible.

Capacity building - Theme lead: Dr Menna Clatworthy

Clinical Research Facilities - Theme lead: Professor Krishna Chatterjee

Imaging - Theme lead: Professor Fiona Gilbert

Inflammation, infection and immunotherapeutics - Theme lead: Professor Ken Smith

Birmingham BRC

Webpage: www.birminghambrc.nihr.ac.uk

The Birmingham BRC would be pleased to host SPARC research trainees.  We have an excellent clinical environment and research infrastructure at University Hospitals Birmingham NHS Foundation Trust and the University of Birmingham.

We have research themes covering a number of inflammatory conditions (arthritis, inflammatory bowel disease, inflammatory liver diseases and sarcopaenia) underpinned by three cross-cutting themes in trial design & delivery, diagnostics & biomarkers, and entrepreneurship & commercialisation.

Diseases of the immune system, which can lead to persistent inflammation, are a group of common and highly disabling conditions which share underlying disease processes. They affect up to 10% of the UK population and this figure is likely to increase with our ageing population. Unfortunately treatment is expensive, rarely curative and often associated with disabling side-effects such as infection.

We are carrying out studies in patients with inflammatory disease in which we are:

1)   Exploring the disease processes that drive these conditions

2)   Focusing on mechanisms that are shared between different conditions allowing us to design rational treatments that will benefit many more patients;

3)   Developing new biomarkers that allow us to select the best new treatment for each patient

4)   Testing new treatments that switch off or re-calibrate the overactive immune system that underpins these diseases.

Please contact bridget.gunson@uhb.nhs.uk  for more information about SPARC placements in Birmingham

Oxford Health BRC

Webpage: https://oxfordhealthbrc.nihr.ac.uk/

Improving brain health: the future in mind

The NIHR Oxford Health BRC is a partnership between Oxford Health NHS Foundation Trust and the University of Oxford.

We aim to bring the best science to the complex problems of mental disorders and dementia. These conditions are major causes of global disability and urgently need better treatments.

Our patients deserve the same research excellence as in other areas of healthcare, and will help inform our research at each key step. We aim to transform discovery science into new treatments which will deliver personalised, precision care. We will harness digital and new technologies so that our solutions can have global reach.

Research themes

Adult Mental Health

Older Adults and Dementia

Precision Psychological Treatments

Cross-cutting research themes

Clinical Research Infrastructure and Experimental Medicine

Informatics and Digital Health

Neuroimaging and Cognitive Neuroscience

Patient and Public Involvement

Training

Contact: tamara.lewin@psych.ox.ac.uk

Applied Research Collaborations (ARCs)

ARC South London

Webpage: www.arc-sl.nihr.ac.uk/

We would be keen to host SPARC candidates at South London ARC, where our work encompasses:

Implementation science and research through NIHR ARC South London which includes Kings Improvement Science and Centre for Implementation Science, and an active Implementation and Improvement Science research group based at St George’s, University of London

  • Design of trials of complex interventions and process evaluation.
  • The Health Informatics team can offer the following training:
  • Decision aid methods and tooling
  • Expertise in developing auditable and reproducible solutions
  • GP EHR integration environment
  • Technologies for semantic mapping
  • Links to Digital Catapult London and their SMEs

For further information visit: www.kingsimprovementscience.org/

ARC West Midlands

Webpage: https://www2.warwick.ac.uk/fac/med/about/centres/clahrc/ 

  • Host institution is University Hospitals Birmingham NHS Foundation Trust
  • Academic institutions are: University of Warwick, University of Birmingham and Keele University
  • Service Themes are: Long Term Conditions; Acute Care Interfaces; Integrated Care in Youth Mental Health; Maternity)
  • Cross-Cutting Themes are: Organisational Science; Research Methodology, Informatics and Rapid Response)
  • Practical implementation and evaluation of research combined with expertise in trial design and complex evaluations
  • Expertise in organisational development and change

ARC Wessex

Webpage: http://www.arc-wx.nihr.ac.uk

ARC Wessex has four research themes: Ageing and Dementia (National ARC Lead), Healthy Communities, Long Term Conditions and a cross-cutting theme looking at Workforce and Health Systems.

Our researchers are based across the region at the University of Southampton, University of Portsmouth, University of Winchester and Bournemouth University and embedded in health and care providers. We would welcome SPARC placements in a specific research theme, with the possibility to combine it across different HEIs. We would also welcome placements across themes.

Please contact the ARC Wessex central team as a first point of contact for the SPARC via email at arcwessex@soton.ac.uk.

ARC East of England

Webpage: http://www.arc-eoe.nihr.ac.uk

ARC EoE has seven research themes: Inclusive Involvement in Research for Practice-Led in Health and Social Care; Population Evidence and Data Science; Health Economics and Prioritisation in Health and Social Care; Palliative and End-of-Life Care; Mental Health over the Life Course; Ageing and Multi-Morbidity; Prevention and Early Detection in Health and Social Care.

Our researchers are based across the region at the University of Cambridge, University of Hertfordshire, University of Essex and University of East Anglia.We would welcome SPARC placements in a specific research theme, with the possibility to combine it across three different HEIs. We would also welcome placements across themes, e.g. specific aspects of dementia research with PPI and health economics.

Please contact Prof Eneida Mioshi as a first point of contact for the SPARC call: e.mioshi@uea.ac.uk

ARC Northwest London

Webpage: http://www.arc-wx.nihr.ac.uk

Our vision is for researchers, healthcare staff, patients, carers and the community to work in partnership on real world problems. Over the last 10 years we have produced and developed methods in areas such as patient, public and community engagement and involvement (PPCEI), capacity and capability building, measurement for improvement, eLearning and a systematic and transferable approach to support the translation of evidence into practice and achieve improvements in health and social care for patients and the population in NWL and the UK.

ARC NWL would be keen to host SPARC candidates who are keen to share learning and improve their knowledge in the areas of our expertise which include:

  • Understanding and applying the tools and techniques of improvement and implementation science. We have expert researchers who have published on the quality improvement tools and techniques, their uses, fidelity of use and have developed and adapted techniques such as the Driver Diagram (the new Action Effect Diagram and method), process mapping, Plan-Do-Study-Act (PDSA) or small cycle change, sustainability tool (Long Term Success) and stakeholder engagement. Contact Julie Reed julie.reed02@imperial.ac.uk
  • Patient, public and community engagement and involvement is a priority within our work and we have academic and practical expertise. We have an exchange network where we meet regularly with a network of patient, public and community members who advise us and our programme, we also are conducting research on this and the best ways in which to engage and build relationships with stakeholders. Contact Rachel Matthews r.matthews@imperial.ac.uk
  • The measurement of improvement is key within our programme and we have both practical and academic expertise in understanding the processes of identifying and collecting data for improvement, engaging with frontline staff to enable and encourage their data collection (both process and outcome measures) and building their capacity in using run charts, SPC charts and enabling routine data review to drive improvement. Contact Tom Woodcock thomas.woodcock99@imperial.ac.uk
  • Emergency care and urgent care is a specialism within our work, we work in close contact with the Urgent Care Collaborative and have experience in ambulatory care projects, virtual wards and other innovations that can help facilitate the challenges currently faced by emergency medicine. Contact Mila Marinova m.marinova@imperial.ac.uk
  • Capacity building is a priority for our programme and we have extensive experience and learning to share on using Collaborative Learning Theory, Action Learning Theory and a range of interactivepedagogies to build capacity and skill in using improvement science on thefrontline, we have both practical and academic research experience in understanding the best ways to facilitate and support improvement science. Contact Rowan Myron r.myron@imperial.ac.uk
  • Clinical specialities – Heart Failure, child population health, breathlessness, multi-morbidities and frailty. Contact Liz Evans liz.evans@imperial.ac.uk

ARC South West Peninsula

Webpage: https://www.arc-swp.nihr.ac.uk

PenARC is a collaboration between NHS Trusts across Cornwall, Devon and Somerset and the Universities of Exeter and Plymouth. We have a shared commitment to improving health outcomes and increasing capacity regionally and nationally through innovative applied health research and generate, make sense of, and implement evidence to benefit patients and our partners in the NHS.

Our work is grouped into five broad themes:

  • Mental Health
  • Dementia
  • Public Health
  • Complex Care
  • Methods for Research & Improvement

Within these areas we have particular expertise in:

  •         Child Health
  •         Ageing and Rehabilitation
  •         Operational Research and Modelling
  •         Evidence Synthesis
  •         Implementation Science
  •         Cluster RCTs

 Details of individual projects within each theme can be found on our website.We would be delighted to host a researcher on a SPARC award. Please feel free to get in touch with Vicki Goodwin v.goodwin@exeter.ac.uk for more information or to talk about a potential placement. Find out more out about the work that we do by visiting our website: http://clahrc-peninsula.nihr.ac.uk/

ARC West

Webpage: https://arc-w.nihr.ac.uk

Our applied health research aims to provide equitable, appropriate, and sustainable health and care across the West. The programme focuses on projects in the areas of public health and prevention, mental health, integrated and optimal care, and healthier childhoods. Our researchers are based in four teams, focused on their expertise in research methodologies: behavioural and qualitative science, applied data science, health economics, and evidence.

All our research projects have the cross-cutting themes of evaluation, patient and public involvement, and training and capacity building, running through them. Research projects are carefully selected from ideas and projects submitted from our health and care community.

Examples of research projects in the above areas are shown below:

    Behavioural and qualitative science – Understanding what causes delays in discharging frail and elderly patients from hospital

    Applied data science - Understanding self-harm using Bristol Self-Harm Surveillance Register data

    Health economics -  Why we need to improve the evaluation of surgical procedures using shoulder surgery as an example

    Evidence - Can selective nerve root blocks help diagnose patients who need lower back surgery? A systematic review

There is particular expertise in the following methodological areas:

  • Evidence reviewing and/or synthesis
  • Analysis of routine NHS data
  • Qualitative implementation research

For a full list of current research projects see the website.

Initial Contact: Professor Selena Gray, Capacity Development Lead  Selena.gray@uwe.ac.uk

ARC North West Coast

Webpage: http://www.clahrc-nwc.nihr.ac.uk/index.php

Expertise/strengths:

  •  We have areas of expertise in all of our cross cutting and research themes.

- Cross-cutting themes:

Care and Health Informatics - Building data science infrastructure, skills, and capacity. 

Methodological Innovation, Development, Adaptation and Support (MIDAS) - Expertise in Evidence Synthesis; Health Economics; Statistics, Trials and other study designs; Implementation Science and Innovation.

Evaluation Health and care across the life course - Developing collaborative     programmes where life stages or circumstances are the focus of interest and implementation with a focus on health inequalities.

- Research themes:

Equitable place-based health and care - Developing sites for local action on social determinants of health inequalities and equitable ‘place-based’ integrated health and social care; Building capacity for co-producing evidence-based improvements in health and care: in agencies, the workforce, communities and individuals.

Improving population health - Developing effective local action on the    determinants of health and health inequalities; Rapid evaluation of public health action and translation of evidence into practice.

Person-centred complex care - Improving care delivery and efficiency and reducing health inequalities; Delivering research and implementation projects that cross the barriers of primary, secondary and tertiary NHS care, and social care.

  •  IMPlementation And Capacity building Team (IMPACT) supports implementation of ARC Member initiatives, using robust research methods, and the creation of Connected Research Communities of ARC Members, to work collaboratively on projects of common interest. We have developed strengths in implementation science, including the writing of implementation plans, guides and evaluations in collaboration with our ARC NWC members.

 

  • ARC NWC aims to make sure that all of our activities have the potential to contribute to reducing inequalities in health. We have a body of expertise in all aspects of addressing health inequalities including development of a Health Inequalities Assessment Tool.

 

  • Public participation is a key part of ARC NWC research. We have lots of experience embedding the involvement of public members/patients within research projects and engage with and involve the public in all activities.

ARC East Midlands

Webpage: http://www.arc-em.nihr.ac.uk/ 

ARC East Midlands would be interested in hosting SPARC candidates who are keen to share learning and improve their knowledge in the areas of our expertise which include:

  • The Centre for Black and Minority Ethnic Health (specialising in community engagement / research in traditionally seldom heard populations);
  • Operational implementation – working collaboratively with our Implementation Hub to get innovation into practice (more like commercial marketing than implementation research);
  • Supporting Clinical Academic Careers for Nurses, Midwives and Allied Health Professionals;
  • Allied, impactful health and social care research exploring Multimorbidities, Mental Health, Stroke, Frailty, Care Homes, plus Big Data, Health Inequalities, e-health / digital health and implementation research

ARC Yorkshire and Humber

Webpage: https://www.arc-yh.nihr.ac.uk

 The ARC YH warmly invites early career researchers to visit us. We have nine themes in the ARC covering a range of clinical areas.

  • Translating knowledge into action.
  • Evidence based transformation with the NHS.
  • Health economics and outcome measurements.
  • Telehealth and care technologies.
  • Public health and inequalities
  • Primary care based management of frailty in older people.
  • Avoiding attendance and admissions in LTC.
  • Mental health co-morbidities.
  • Healthy children. Healthy families.

Our unique strengths include working with industry, health inequalities research, work with designers to support co-production in research, the development of research derived actionable outputs, and Trials within Cohort (TwiCs) methodologies. We have an interest in supporting Nurses, Midwives and Allied Health Professionals in developing clinical academic careers. Please contact the relevant theme manager to discuss a placement with us; or Jo Cooke (jo.cooke@sth.nhs.uk) for more generic questions on placements.

ARC North Thames

Webpage: www.arc-nt.nihr.ac.uk

ARC North Thames would be delighted to host a researcher on a SPARC award. Our website has details about the work we do, and please feel free to get in touch for more information or to discuss potential placements.

About us: ARC North Thames works with academics, NHS and local authority partners, industry partners, patients and the public to conduct innovative applied health research and to support its implementation for the direct benefit of patients, the wider population and the NHS in our region and nationally. 

Our work is grouped into five broad Themes (details of the individual projects within each Theme can be found on our website):

  •       Mental Health
  •       Multi-morbidity
  •       Population Health and Social Care
  •       Innovation and Implementation Science
  •       Health Economics and Data 

We have also been designated national ARC lead for population health.

We also have expertise in a range of areas that run through all of our Themes including:

  • Health economics
  • Qualitative research
  • Using research evidence effectively
  • Digital health
  • Analysing healthcare data / Big data
  • Operational research    
  • Patient, public and community involvement

ARC Oxford and the Thames Valley

The Oxford and the Thames Valley Applied Research Collaboration would be delighted to host a researcher on a SPARC award. We work with local and national partners to address some of the nation’s most pressing challenges faced by the health and care system, including dementia, cardiovascular heath, obesity and mental health. Our website has details about the research areas we are involved with and links to the research groups involved. Please get in touch for more information or to discuss potential placements.

Webpage: www.arc-oxtv.nihr.ac.uk

Email: arc-otv@nihr.ac.uk

Patient Safety Translational Research Centres (PSTRCs)

NIHR Yorkshire and Humber Patient Safety Translational Research Centre

Webpage: http://yhpstrc.org/

The Yorkshire and Humber PSTRC would like to extend a warm invitation to NIHR Academy Members to apply for SPARC placements in a number of areas of quality and safety research. Based across the University of Leeds and the Bradford Institute for Health Research, we are a multi-disciplinary group of researchers, clinicians and patient representatives, whose aim it is to develop innovative solutions to patient safety problems.  We would be happy to support SPARC applications in the following research areas:

  • Patient and family involvement in patient safety
  • Workforce well-being and patient safety
  • Positive deviance approaches and methods
  • Digital and novel technological solutions to improve patient safety
  • Experience-based co-design as applied to healthcare improvement
  • Medicines optimisation and de-prescribing
  • Supporting transitions across care boundaries for older people
  • Personal resilience and quality and safety
  • Involving patients and families in serious incident investigations

Should you be interested in applying for a SPARC placement with us, please contact Dr Beth Fylan, Programme Manager (b.fylan@bradford.ac.uk) or Dr Jane O'Hara, Theme Lead and Training Lead (jane.o'hara@bthft.nhs.uk) to discuss your ideas.

NIHR Greater Manchester Patient Safety Translational Research Centre

Webpage: http://www.patientsafety.manchester.ac.uk/research/themes/

The NIHR Greater Manchester Patient Safety Translational Research Centre (Greater Manchester PSTRC) is a partnership between The University of Manchester and Salford Royal NHS Foundation Trust; in collaboration with the University of Nottingham. We would like to extend a warm invitation to apply for a SPARC placement with us.  The Greater Manchester PSTRC conducts research studies within four themes: Safety informatics, medication safety, safer care systems and transitions, and safety in marginalised groups. We work with NIHR ARCs, BRCs, PSSRUs,  AHSNs and Patient Safety Collaboratives, as well as NHS, local authority and industry partners within an Academic Health Science System - HInM (Health Innovation Manchester). We have a strong involvement and engagement agenda working with health and care professionals, the NHS, local authorities, industry and patients, carers and members of the public; within the Greater Manchester Health and Social Care system. We focus on primary care and transitions between care including hospitals and social care. Capacity building is integral to our work, which includes 12 PhD students.

 NIHR Trainees are encouraged to apply for SPARC awards within the following topics or methodological fields:

 Topics

  • Safety systems in clinical pharmacy and mental health
  • Healthcare quality and safety in vulnerable or marginalised groups
  • Legal, ethical and governance issues at transitions of care
  • Safety in primary and community care
  • Big data

Methods

  • Use of large primary care and other databases for epidemiological studies
  • Informatics and artificial intelligence
  • Co-designing and producing interventions with service stakeholders (including PPI with patients and carers)
  • Mixed-method evaluations of interventions or service delivery

More information is available at:

http://www.patientsafety.manchester.ac.uk/

Please contact the Centre Director, Professor Stephen Campbell (stephen.campbell@manchester.ac.uk) or the Centre Training Lead, Prof Roger Webb (roger.webb@manchester.ac.uk) to discuss your proposals for a SPARC award / placement.

Medtech and In-vitro diagnostics Cooperatives (MICs)

Webpage: https://www.nihr.ac.uk/partners-and-industry/industry/access-to-expertise/medtech.htm

The NIHR Medtech and In vitro diagnostics Co-operatives (MICs) launched on 1 January 2018. The NIHR MICs replace the NIHR Healthcare Technology Co-operatives (HTCs) and NIHR Diagnostic Evidence Co-operatives (DECs), incorporating and retaining the remits of both.

NIHR MICs build expertise and capacity in the NHS to develop new medical technologies and provide evidence on commercially-supplied in vitro diagnostic (IVD) tests. Leading NHS organisations act as centres of expertise, bringing together patients, clinicians, researchers, commissioners and industry.

More than £14 million over 5 years has been awarded across 11 NIHR MICs. If you are interested in working with the NIHR MICs or would like more information, please contact the NIHR Office for Clinical Research Infrastructure: nocri@nihr.ac.uk.

Clinical Research Facilities (CRFs)

Webpage: https://www.nihr.ac.uk/about-us/how-we-are-managed/our-structure/infrastructure/clinical-research-facilities-for-experimental-medicine.htm

Whilst CRFs vary due to local need, all will include the following:

  • Outpatient and usually inpatient facilities;
  • Support for high intensity studies;
  • Highly trained dedicated research support and management personnel;
  • Specialist equipment and laboratories to conduct a variety of research studies;
  • Standard Operating Procedures to ensure studies are conducted to GCP/ Research;
  • Governance Framework (and its successor) requirements.

NIHR Research

School for Primary Care Research

Webpage:  https://www.spcr.nihr.ac.uk

From the SPCR perspective we have significant expertise in the design and conduct of pragmatic clinical trials, patient and public involvement and engagement, using big data (e.g. CPRD), qualitative research methods, e-interventions and systematic reviews and meta-analysis. Our work is firmly rooted in primary care, so we work with populations with the full spectrum of disease. We have specific clinical areas of expertise (musculoskeletal, mental health, antibiotic prescribing, dementia, anxiety and depression,  behaviour change, patient safety and multi-morbidity - to name just a few!)

School for Public Health Research

Webpage: www.sphr.nihr.ac.uk 

The NIHR School for Public Health Research is a partnership between eight leading academic centres with excellence in applied public health research in England*.  The School aims to build the evidence base for effective public health practice. Our research looks at what works practically to improve population health and reduce health inequalities, can be applied across the country and better meets the needs of policymakers, practitioners and the public.  The NIHR School for Public Health Research has three research programmes alongside three cross-cutting themes. 

Research programmes;

  • Children, young people & families
  • Public mental health
  • Places and communities 

Cross-cutting themes;

  • Health inequalities
  • Changing behaviour at population level
  • Equitable and efficient public health systems

Please contact sphr@ncl.ac.uk for further information.

* The NIHR School for Public Health Research is a partnership between the Universities of Sheffield, Bristol, Cambridge, Imperial and University College London; The London School for Hygiene and Tropical Medicine (LSHTM); the LiLaC collaboration between the Universities of Liverpool and Lancaster and Fuse; The Centre for Translational Research in Public Health, a collaboration between Newcastle, Durham, Northumbria, Sunderland and Teesside Universities.

School for Social Care Research

Webpage: https://www.sscr.nihr.ac.uk/

The NIHR School for Social Care Research (SSCR) is in its third 5-year phase and is a partnership between seven leading academic centres of excellence in social care research in England (namely LSE, KCL and the Universities of Bristol, Kent, Manchester, Birmingham and York).  The School’s remit is to contribute to building the evidence base for adult social care practice in England. Our research spans all aspects of adult social care, including different client groups and needs (for example, older people, people with living with dementia, or with learning disabilities, or with physical disabilities, or with mental health problems) and in different care settings (e.g. care homes, people’s homes and communities).  Members of the School bring a very wide range of disciplinary, theoretical and methodological expertise to all aspects of adult social care.